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Today, with the rapid development of modern medical technology, more and more innovative means have been applied to the treatment of cancer, especially in the treatment of gynecological malignant tumors. Cervical cancer is the most common gynecological malignant tumor in women, and the progress of its treatment is particularly significant. In recent years, the combination of 3D printing technology and painless after-loading treatment has provided a more accurate and comfortable treatment for cervical cancer patients. Dai Yongmei, chief physician of Fuzhou University Affiliated Provincial Hospital, took the lead in developing 3D printing after-loading + painless after-loading in Fujian Province to achieve the perfect combination of precision and comfort. This article will explore in detail how this innovative technology is a boon for patients. 1. Traditional treatment of cervical cancer and its limitations The treatment of cervical cancer mainly includes surgery, radiotherapy and chemotherapy. The effect of radiotherapy for early cervical cancer is comparable to that of surgery, while radiotherapy is the preferred treatment for advanced cervical cancer. Radiotherapy includes external irradiation and brachytherapy, which can be combined to cure cervical cancer more effectively. However, the traditional after-loading therapy is often accompanied by intense pain, which makes some patients difficult to tolerate, thus affecting the therapeutic effect. Traditional afterloading therapy is usually intracavitary standard applicator radiotherapy or implantation radiotherapy in the awake state of the patient. In the process of dilating the uterus, exploring the uterus, placing the applicator, inserting the needle beside the uterus, and adjusting the needle, patients often feel strong pain, especially those with narrow vagina or need to dilate the uterus. For most advanced cervical cancer, the tumor often invades the uterus, pelvic wall and bladder rectum in a high position. If we want to achieve a satisfactory radiotherapy dose distribution to ensure the efficacy, we need a certain depth and height of interpolation. However, it is difficult for patients to cooperate with doctors to complete the operation, which directly affects the treatment effect, and some patients even give up treatment because of pain. 2. Innovative application of 3D printing after-loading technology In order to solve the pain points of traditional after-loading treatment, 3D printing after-loading technology came into being. 3D printing technology scans the patient’s individualized anatomical information through CT, and uses artificial intelligence computer to design a three-dimensional, omni-directional enhanced irradiation of the tumor site, while reducing or shielding the irradiation of normal tissue. This technology makes radiotherapy more accurate, can effectively avoid the blind area of the target area, and achieve the ideal radiation coverage and dose. Specifically, 3D printing technology can customize a highly personalized multi-channel applicator, and through this special auxiliary device, patients can be treated with “private customization” of three-dimensional implantation. The needle on the applicator goes deep into the tumor, and the radioactive source reaches the depth of the tumor from these channels, accurately attacking and eliminating cancer cells. Because each patient’s tumor morphology and location are different, each patient’s afterloading treatment plan is unique. 3D printing technology not only improves the accuracy of radiotherapy, but also makes the needle insertion process more stable and smooth, effectively reducing the pain of patients in the process of needle insertion. This technique is particularly useful for large tumors as well as eccentric tumors. Through the after-loading technology of CT-guided intracavitary combined interstitial implantation, it can ensure that the radioactive source reaches the depth of the tumor accurately, while protecting the normal organs and tissues around the tumor and reducing side effects. 3. Painless afterloading therapy: improve patient comfort Although 3D printing afterloading technology improves the accuracy of radiotherapy, some patients still can not tolerate the pain during afterloading therapy because of the low pain threshold. Therefore, the emergence of painless after-loading therapy technology has further improved the comfort of patients. The painless after-loading treatment was carried out with the cooperation of the anesthesiology team. Through anesthesia technology, patients can receive treatment in a completely painless state. This treatment method not only effectively alleviates the fear and tension of patients, but also greatly improves the cooperation of patients in the operation process, thus increasing the success rate of doctors’operation. 4. Future prospects With the continuous development and improvement of 3D printing technology and painless after-loading treatment technology, its application prospects in the treatment of gynecological malignant tumors will be broader. In the future, we can look forward to the application of more innovative technologies to provide patients with more accurate, comfortable and efficient treatment programs. In a word, the combination of 3D printing after-loading technology and painless after-loading treatment provides a more accurate and comfortable treatment for cervical cancer patients. This innovative technology not only improves the treatment effect, but also greatly improves the comfort of patients, so that more patients can successfully complete the treatment and regain their health. Cervical cancer Gynecological diseases Gynecological cancer Gynecological tumor