Carbon pyroacnein is one type of antibacterial antibiotic that has a wide spectrum and a high level of antibacterial activity.
I. Structural characteristics
The chemical structure of the carbon cyanide antibiotics is similar to that of the penicillin and capisculin, all of which have β-neamide rings. However, its structure is unique in that it connects a carbon cyanide bicyclic structure to one carbon atom of the β-neamide ring, which gives it good chemical stability and high tolerance for β-neamide. This particular structure is like a “protective suit” for antibiotics that is resistant to bacteria-generated enzymes that damage the β-neamide ring.
II. Antibacterial spectra
It has a strong antibacterial activity for both the Guerranca and the Geran positive. Bacillus intestinal bacteria such as coliform, creberella pneumonia, etc. in the gerranium cactus are effective in inhibiting the synthesis of cell walls and thus contributing to microbicide. It’s like a precise “key” that inserts a “lockhole” in the synthesis of these bacterial cell walls to stop their cell wall construction.
There are also better antibacterial effects on copper-green bogus. The BCM is a common hospital-infected pathogen that is more drug-resistant, while the carbon acne antibiotics are able to overcome some of its resistance mechanisms to antibacterial efficacy.
There is also some antibacterial activity in the case of gland positive fungi, and in the case of golden grapes, coagulation enzymes, but relatively weak in the case of methoxysilin yellow grapes.
III. ROLE MECHANISMS
Carbon pyroacylene antibiotics are mainly used to inhibit the synthesis of bacterial cell walls by inhibiting bacterial cell glacial synthetic enzymes. The cytowall of bacteria is like a “protective shield” that is essential to the survival of bacteria. When antibiotics inhibit the synthesis of cell walls, bacteria, acting under internal osmosis pressure, are unable to form properly, resulting in bacteria ‘ swelling, rupture and death.
IV. Clinical applications
Such antibiotics are used mainly to treat serious bacterial infections. For example, access to treatment for sexually transmitted pneumonia in hospitals plays a key role. Hospital access to pneumonia is often caused by drug-resistant bacteria, which can be effectively countered by carbon-acrylated antibiotics, helping patients to mitigate inflammation and respiration.
In the case of complex abdominal infections, the wide-spectrum antibacterial properties of carbon pyroacne-antiphyllene can cover most of the possible pathogens and provide a good therapeutic effect due to a possible combination of bacteria.
It can also be used for the treatment of serious systemic infections such as sepsis. Sepsis is a critical disease, bacteria and their toxins enter the blood cycle, and carbon-cyanide antibiotics can quickly control bacteria ‘ reproduction, reduce the production of toxins and buy time for the rehabilitation of patients.
Drug resistance
With the widespread use of antibiotics, the problem of resistance to carbon pyroacne is also increasing. Bacteria can hydrolyse the β-neamide rings that produce carbon cyanide antibiotics, thus depriving them of antibacterial activity. In addition, bacteria can reduce the concentrations of antibiotics in bacteria by altering the permeability of the outer membrane protein and enhancing the active exterior pump system, thereby creating resistance. It is a constant “upgrading” of the bacteria to avoid antibiotics.
VI. Representing drugs
Common biobiotics include amphetamine, meropentine, etc. Alhamphetamine is usually used in conjunction with Westenedy, which can inhibit the hydrolysis of the adrenal dehydrogenase to Amphetamine, thus increasing the stability and antibacterial activity of the alhamphetamine in the body. Meropenan is similar to amphetamine in terms of antibacterial spectrometry and antibacterial activity, but may have some advantages in some respects, such as the safety of the central nervous system.
