It’s about anti-fluent oesophagus.
The basic concept of anti-fluent oesophagitis Reflux Esophagis, RE, is a common digestive system disease, mainly due to inflammation of oestic mucous membranes due to the anti-fluencillation of stomach content. The stomach content consists mainly of stomach acids, stomach protein enzymes and cholesterol, which are more irritant and corrosive to oesophagus mucous membranes. The pathological mechanism for anti-fluent oesophageal inflammation involves a number of aspects such as duct-to-ecophagus disorders, reduced edible removal capacity and impaired edible mucous barrier functions. Long-term retrenchment of the stomach content can not only lead to oesophagus inflammation, but can also lead to serious complications, such as narrow oesophagus and Barrett. The clinical manifestations of anti-fluent oesophageitis are diverse, including typical heart burns, anti-acid symptoms, and symptoms of atypical chest pains, difficulty of swallowing. The disease seriously affects the quality of life of patients and requires timely diagnosis and treatment. (ii) Epidemiological characteristics of anti-fluenza. There is an increasing trend in the incidence of anti-fluenza worldwide, particularly in Western countries, where prevalence ranges from 10 to 20 per cent. In Asian countries, although the prevalence rate is relatively low, there has also been a significant increase in recent years. According to a large-scale epidemiological survey, the incidence of anti-fluenza in China is estimated at 5.77 per cent, and there is a trend of annual increase. This trend of growth is closely linked to changes in the way of life in modern society, such as the westernization of the diet, increased stress at work and lack of exercise. The age at which the disease occurs is concentrated in the middle and senior age groups, but the number of young patients has been increasing in recent years. There are slightly more male patients than female patients, but there has been a significant increase in female patients following menopause. Obesity is a major risk factor for anti-fluenza, and the higher the BMI, the higher the risk of disease. Smoking and alcohol consumption are also a risk factor for the disease, and long-term smoking and alcohol consumption can impair the function of the bicep under the oesophagus and increase the risk of re-flow of stomach contents. The incidence of anti-fluenza is also related to certain specific occupations and life habits. For example, long-term employment in occupations requiring long standing or bending jobs, such as cooks, construction workers, etc., is at higher risk of disease. Life habits such as eating at night, lying down immediately after meals and wearing tights can also increase the risk of anti-fashion dysentery. Despite the high incidence of anti-fluenza, many patients are not receiving timely diagnosis and treatment. Some sufferers suffer from mild or unusual symptoms, which do not attract sufficient attention, leading to a gradual increase. Therefore, raising public awareness of anti-fluenza and strengthening early screening and diagnosis are important for controlling the condition and improving the quality of life of patients. II. The causes and symptoms of anti-fluent oesophagus disease (I) Impairment of the oesophagus under the oesophagus. The oesophagus under the oesophagus (Lower Esophatic Sphincter, LES) is a entanglement of muscles that are located at the oesophagus and stomach connections, the main function of which is to prevent the counter-inflow of gastrophagus into the oesophagus. Under normal circumstances, LES forms a high-pressure zone at the lower end of the edible tube, and when swallowed, the LES is temporarily relaxed, allowing food to pass and then quickly returning to stress and preventing a reversal of the stomach content. However, when LES is dysfunctional, the maintenance capacity of such high-pressure areas is reduced, resulting in a high risk of re-inflow of stomach acid and gastric content to the oesophagus, which in turn leads to the inflammation of the anti-fluent oesophage. The reasons for the LES functional impairments are varied, including lower LES pressure, increased frequency of LES laxity and shorter LES lengths. The decrease in LES pressure may be due to neuromuscular disorders, a decrease in LES smooth muscle cell function or a decrease in LES smooth muscle cell number. The LES overspill refers to the spontaneous laxity of the LES in the absence of oscillation, which is more common among persons with anti-fluent oesticitis. A reduction in the length of the LES may lead to a reduction in LES resistance to stomach pressure, further exacerbating the retrogressive phenomenon. Certain factors, such as obesity, smoking, drinking and high-fat diet, can also adversely affect LES functions. Obesity increases the burden of pressure on LES by increasing the abdominal pressure; smoking and drinking reduces the tension of LES and increases the incidence of retorts; and high fat diets contribute to retorts by slowing down stomach emptiness and increasing stomach pressure. (ii) The effects of gastric acid and gastroprotease. The pH for gastric acids is usually between 1.5 and 3.5, and this strong acidic environment has a very strong corrosive effect on oesophagus mucous membranes. Under normal circumstances, edible mucous membranes are protected against gastric acid erosion through a range of defensive mechanisms, but when these mechanisms are damaged, the stomach acid causes direct damage to the edible mucous membrane and inflammations. The gastric protein enzyme, activated with gastric acid, can decompose the protein composition of the fungus membrane, further exacerbating the mucous membrane damage. The activity of the stomach protein enzyme is closely related to the pH of the stomach acid, which increases significantly when the pH is below 4. As a result, co-effects of stomach acid and stomach protein enzymes increase the vulnerability of oesophagus mucular membranes to damage, leading to inflammation. In addition to acute inflammation, the retrenchment of stomach acids and gastroprotein enzymes can lead to chronic inflammation, and may even develop into serious complications such as a narrow edible tube and a barrett. As a result, the control of gastric acids and the reduction of the activity of gastroprotease is one of the important tools for the treatment of retroftoritis. (iii) Absorption of oesophagus mucous membranes These defence mechanisms include the mucous barrier, the close connection of upper skin cells, mucous blood flow, mucous membrane repair capacity, etc. When these defensive mechanisms are damaged, the resistance of the oesophagus membranes to gastric acids and gastroprotease is reduced, making them vulnerable to inflammation. The mucous barrier is the first line of protection for the edible mucous membrane, consisting of the mucous glucous glucose that can be combined to protect the mucous membrane surface. The protection of the mucous barrier is reduced when the mucous genus is reduced or its quality is reduced, and the edible mucous membranes are more vulnerable to damage. The close connection of upper skin cells is the second line of defence of the oesophagus membrane, which prevents gastric acid and gastroprotease from permeating into the lower membrane. Genetic factors are also an important factor in the impact of anti-fluenza. Studies have shown that the variability of certain genetic genes is related to the susceptibility of anti-fluent oesophageitis. For example, LES functional impairments, excessive gastric acidization and impaired edible mucous membrane defences may be associated with genetic factors. Thus, for patients with family history, greater attention should be paid to the prevention and treatment of anti-fluenza. III. Clinical manifestations of anti-fluent oesticitis (i) Typical symptoms These symptoms tend to increase after meals or when lying down, especially at night. The inverse of the stomach content refers to the reverse flow of the stomach content to the oesophagus, where patients often feel acidic or bitter substances pour into their mouths, sometimes accompanied by gas or nausea. Heart fever, in turn, refers to the fever behind the chest, which can be extended upwards from the lower part of the chest to the throat, and can affect the daily life and the quality of sleep of the patient when it is severe. Breast pains are also more common among patients with anti-fluent oesophagus, usually manifested in a feeling of oppression or stinging behind the chest, sometimes misdiagnosed as heart pain, and need to be identified through further examination. In addition to the above-mentioned main symptoms, some patients may suffer from swallowing difficulties (e.g., when swallowed, food is caught in the duct) and swallowing pain. The difficulty of swallowing usually occurs when the disease progresss to a moderate degree, possibly because of the narrowness of the oesophagus. Ingestion pain is manifested in the pain of swallowing, especially when the solid food is swallowed. These symptoms not only affect the dietary habits of patients, but may also lead to malnutrition and weight loss. (ii) Atypical symptoms and complications Atypical symptoms of retrofluent dysentery are varied, including dysentery in the throat, acoustic acoustic, chronic cough, asthma, tooth acne erosion, etc. Inhabitants in the throat are often manifested in dry throats, exotic senses or frequent throat cleaning, and these symptoms may be the result of inflammation due to a retrenchment of stomach acid to the throat. Hissings tend to be found in long-term retrogressive patients, and gastric acid reflux to acoustic cord can cause acoustic inflammation and change of sound. Chronic cough and asthma are also more common among people affected by anti-flow oesophagus, particularly at night, which may be associated with gastrophate irritation, leading to respiratory inflammation and convulsions. A further atypical symptom of concern is tooth aroma erosion, which can lead to gradual erosion of tooth aroma from the teeth ‘ surface, as evidenced by wear and sensitivity from the teeth ‘ surface. Long-term dental palate erosion not only affects beauty but can also lead to dental dysfunction and increase the risk of oral disease. In addition to atypical symptoms, anti-fluenza can cause a series of complications, the most serious of which is the Barrett’s esophagus. The Baret duct means that the normal top skin of the lower part of the duct is replaced by the top skin of the column, and this pathological change increases the risk of oesophagus cancer. Therefore, regular endoscopy and biopsies are important for patients suffering from chronic anti-fluent dysentery in order to detect and process the Baret oes at an early stage. Another common complication is the constriction of edible pipes, which can be fibroized by long-term inflammation and repair processes, which can form a narrow section and seriously affect the osmosis function of patients. Patients with narrow edibles often experience difficulties in performing sexual ingestion, especially for solid foods, and in serious cases even require under-scope expansion or surgical treatment. Esophagus is also an important complication of anti-flow oesophagus, which is that part of the stomach enters the oesophagus through the oephagus, making it easier for stomach contents to reverse to the oesophagus. Esophagus not only exacerbates the symptoms of anti-fluenza but may also cause other symptoms, such as chest pain and abdominal pain, which need to be diagnosed by means of video-testing and appropriate treatment in the specific case. The clinical manifestations of retrofluent oesophages include not only typical retrogression of stomach content, heart and chest pain, but also a variety of atypical symptoms and complications. Understanding these symptoms and complications is important for early diagnosis and effective treatment and helps improve the quality of life of patients and prevent the occurrence of serious complications. (i) Clinical performance and physical examination Typical symptoms that are common to patients include post-heart burns (commonly known as “heart” ), anti-acids, gastrics, difficulty of swallowing and chest pains. These symptoms tend to increase after meals, when they lie down or when they bend. Some patients may have atypical symptoms, such as arrhythmia in their throats, hissing, chronic coughing and asthma, which may be associated with a retrenching of stomach acid to the throat or a bronchial. Medical examinations are usually undiscovered, but doctors exclude other possible diseases through detailed medical history inquiries and medical examinations. For example, a doctor may examine the heart, lung and abdominal of the patient to exclude heart, lung and gastrointestinal diseases. Doctors also ask patients about their eating habits, lifestyle and history of medications in order to understand the possible incentives. (ii) Endoscopy and biopsy. Through an endoscope examination, doctors can directly observe the mucous changes in the edible tube. The endoscopy is usually performed under local anesthesia, and the doctor inserts a soft endoscope through the mouth or nasal cavity of the patient to the stomach and to the end of the intestines. Under the lens, doctors can observe changes in the edible mucous membrane, oedema, curvature and ulcer. Based on the degree of variability observed under the endoscope, retroft can be classified in different grades, and the usual classification criteria include the Los Angeles classification system. In the course of an endoscope examination, the doctor can also perform a biopsy, i.e. a small edible mucous tissue for a pathological examination. The biopsy helps to exclude other diseases that can cause similar symptoms, such as oesophagus cancer, oesophagus pathologies, etc. The results of the biopsy provide more detailed pathological information and help doctors to develop more accurate treatment programmes. (iii) 24-hour pH monitoring and resistance monitoring p H monitoring is an inspection method used to assess gastric acid reflux frequency and duration. The examination continuously monitors the change in the pH of the duct within 24 hours by placing a small pH electrode in the patient ‘ s duct. PH below 4.0 is considered to be acidic inverse. Twenty-four-hour pH surveillance can provide important information on the frequency, duration and relevance of back-flow events, help to identify re-fluenza and assess treatment effectiveness. In recent years, resistance monitoring techniques have gradually been applied to anti-fluent oesophage diagnosis. Resistance monitoring detects the back-flow of liquids and gases in the oesophate, not only the back-flow of acids but also non-acids. The 24-hour PH-Construction Joint Surveillance provides more comprehensive reverse information and improves the accuracy of diagnosis. This joint monitoring method applies in particular to patients whose symptoms are not consistent with pH monitoring results, such as those caused by non-acid retrenchment. (iv) Other auxiliary examinations, in addition to the main diagnostic methods described above, may be used to assist in the diagnosis of anti-fluent cuisine. Esophatic manometry is an inspection method to assess the function of the oesophagus, which, by measuring changes in pressure in the various parts of the oesophagus, provides an understanding of the pressure of the oesophagus under the oesophagus and the oesophagus worm function. The oestic pressure helps to remove oesophagus disorders, such as cosmopolitan convulsions and cylindrosis. Barium Swallow is a method of video-screening that allows the person to observe the morphological and motor functions of the cuisine by ingestion of liquids with a transistor, followed by X-rays. Although the diagnosis of retrofluent oesophagus is low, there are circumstances in which valuable supporting information can be provided, such as the detection of dyslexia, vasectomy, etc. The gastrointestinal examination (Gastroyestinal Function Tests) can also be used to assess stomach emptiness and gastrointestinal drive. These examinations, which include gastric emptiness scans, gastroelectric charts, etc., help to understand possible causes such as gastrointestinal emptiness delays and gastrointestinal disorders. Diagnosis of anti-fluent dysentery requires a combination of examination methods and individualized diagnostic programmes based on patient clinical performance and results. Through these examinations, doctors can accurately assess the condition and provide effective treatment advice to patients.
Anti-fluent oesticitis
