Blood sunk fast: a key signal of the disease

Rheumatism is a complex and challenging self-immunological disease, and blood sunk (red cell deposition rate, ESR) is an important test among its many screening indicators. The rapid increase in blood is of many clinical significance in the rheumatism arthritis, and a better understanding of it helps patients and their families to better understand the condition and to cooperate with doctors in effective treatment and management.

First, the “barometer” of inflammation activities tends to be a visual reflection of rheumatism activities. In normal physiology, the erythrocyte has a relatively stable deposition rate in plasma. However, when the inflammation response in patients with rheumatism arthritis is triggered, the immune system releases a large number of inflammatory media, such as tumour cause of death – α (TNF – α), white cell media – 1 (IL – 1), white cell media – 6 (IL – 6). These inflammatory media alter the physical and chemical properties of the various components of the blood, result in reduced charge-to-charge exclusion between red cells, and can easily congregate into one another to form a molybdenum, resulting in a significant increase in the rate of downsinking of red cells, i.e., of blood. As a result, doctors usually use blood sank as one of the important grounds for determining whether an inflammation of the rheumatism arthritis patients is active. If, in regular reviews, patients find a steady increase in blood sunk with symptoms such as severe pain, increased swelling and prolonged morning stagnosis, it is likely that the disease is at a dynamic stage, requiring a timely adjustment of treatment programmes and enhanced anti-inflammatory treatment to control further deterioration.

ii. The key parameters of the assessment of the state of the disease The rapid blood insulation is also of critical value in the assessment of the severity of the condition of persons with rheumatism. In general, the higher the value of blood sunk, the greater the overall severity of the patient ‘ s condition, the greater the degree of joint stress, and the greater the degree of joint damage. However, as the disease develops, the risk of symmetric swelling, pain and even joint malformations, often accompanied by multiple joints, increases significantly when blood sank. When developing a treatment plan, doctors take full account of the parameter of blood sank, taking into account the function of the patient ‘ s joint, the results of a visual examination (e.g. the narrow joint gap shown by X-line, the degree of bone damage) and other laboratory indicators (e.g. rheumatism, C reaction proteins, etc.), to make a comprehensive and accurate assessment of the patient ‘ s condition, with a view to determining appropriate treatment objectives and strategies. More active joint treatment programmes, including the use of a variety of anti-regulatory drugs, biological agents, etc., may be needed for patients with high blood sunk rates to control inflammation as soon as possible, slow down the process of joint destruction and protect joint functions.

In the treatment of rheumatism, sanctuaries are also effective indicators for monitoring the effects of treatment. As effective treatment measures are implemented, inflammation in the patient ‘ s body is gradually brought under control, and blood sunk and normalized. If after treatment, blood sanctuaries are gradually reduced and joint symptoms are mitigated, such as reduced joint pain, swelling and swollen swelling, and reduced morning strangulation, this indicates that the current treatment programme is effective and the doctor recommends that the patient continue the treatment and keep it under review and keep a close eye on changes in blood sanctuaries and other indicators. On the other hand, if, during the treatment process, blood sank remains high, or increases again after a decline, and at the same time there has been no significant improvement or even an increase in the patient ‘ s joint symptoms, this prompts the doctor to revisit the treatment programme to consider whether there are problems such as insufficient drug doses, poor drug treatment, poor patient dependence or the combination of other infections, and to adjust the treatment programme in a timely manner, such as changing the type of drug, increasing the dose of the drug or co-using other assistive treatments, to ensure that it is effective to control the condition and achieve optimal treatment.

4. The reference basis for the prognosis is also of some relevance to the prognosis of patients with rheumatism. The risk of complications such as joint malformations, disability and cardiovascular diseases is relatively high for patients with long-term hemorrhaging and difficult to control. This is because the continuing inflammatory response not only causes direct damage to the joints, leading to loss of joint structures and functions, but also may affect the internal vascular cell function of the whole body, promote the sclerosis of the artery and increase the risk of cardiovascular disease. Thus, in the treatment of such patients, doctors will place greater emphasis on the integrated management of diseases and, in addition to active control of arthritis, on the monitoring and control of cardiovascular risk factors such as blood pressure, blood resin, blood sugar, etc., while strengthening health education of the patients, providing them with guidance on appropriate rehabilitation exercise, maintaining good life habits to reduce the risk of complications and improve their long-term prognosis.

The blood of people with rheumatism is growing as fast as a mirror, reflecting the state of activity of the inflammation, the severity of the condition, the effects of the treatment and the prognosis. Patients should properly understand the importance of blood sanctuaries as an indicator of detection, and actively cooperate with doctors in conducting regular blood sanctuaries and other related examinations so that doctors can keep abreast of changes in the condition in a timely and accurate manner and develop the most appropriate individualized treatment programmes to better control rheumatism, improve the quality of life and live in harmony with the disease.