In the general perception, low immunity is often associated with frequent flu and vulnerability. However, it is surprising that low immunity may also increase the risk of self-immunisation, and what is the connection behind it?
Under normal circumstances, the human immune system, like a well-trained army, is able to identify “self” and “non-me” with precision and to attack external pathogens, such as bacteria, viruses, etc., in order to protect the body from infection and maintain its health. However, when immunity is low, the balance of the immune system is broken, and a series of complex changes are occurring, placing its own immune disease at risk.
First, low levels of immunity may lead to immunosuppressive imbalances. One of the most important cells in the immune system is called regulating T cells, which, like the immune system’s “brakes”, can contain the excess activity of the immune system, sustain immunisation and prevent it from attacking its own tissue. However, when immunity decreases, the functions of the regulating T-cells may be affected and their inhibition may not be effective. It’s like when a car loses a brake and the immune system’s “active forces”, such as the effects of T-cells and B-cells, can over-activate, wrongly identify their normal organization as an alien aggressor, and then launch an attack that triggers their own immune response, leading to their own immune disease.
Secondly, the infection factor plays an important role. People with low levels of immunity are more vulnerable to various pathogens, and certain infections are closely related to the onset of their own immunisation. Some pathogens, such as viruses and bacteria, have antigen structures similar to those of the human body’s own tissue, so-called molecular simulations. When the immune system reacts to these pathogens, because of the similarity of the antigens, it may attack its own organization at the same time, thus initiating its own immunization process. For example, EB virus infections are associated with the occurrence of multiple self-immunisational diseases, such as systematic erythalamus and rheumatitis, which increase the likelihood of self-immunisation when low immunity makes the EB virus more vulnerable to long-term internal survival and sustained stimulation of the immune system.
Moreover, intestinal herbology disorders cannot be ignored. The intestinal tract is the largest immune organ in the human body, and there is a complex and delicate interaction between the intestinal population and the immune system. In cases of low immunity, the balance of intestinal strains can be broken, the number of beneficial bacteria reduced and the number of harmful bacteria increased. This may result in impairment of the intestinal mucous barrier, making it easier for some antigens in the intestinal tract to enter the blood cycle and activate the immune system. In addition, intestinal strains can regulate the separation and functioning of immunosuppressive cells, which can cause abnormal changes in the development and activity of immunosuppressive cells, thus contributing to the development of their own immune status.
In addition, when immunity is chronically low, overall body repair and maintenance mechanisms are affected. The possibility that normal tissues may not be repaired in a timely and effective manner after a minor injury has occurred offers more opportunities for anomalous recognition of the immune system, making it easier for a self-organised organization that is already immunely resistant to attack the immune system, and further increases the incidence of its own immunisation.
Vulnerability to self-immunisation at low levels is the result of a combination of factors. Therefore, maintaining good living habits, such as balanced diet, adequate exercise and adequate sleep, helps to maintain the normal functioning of the immune system and to reduce the risk of self-immunisation. At the same time, more attention should be paid to the health status of people with low levels of immunity, periodic medical examinations should be conducted, possible health problems should be detected and addressed in a timely manner, and appropriate measures should be taken, under the guidance of a doctor, to increase immunity and prevent diseases.
