Controlling blood urea levels in normal range is one of the key objectives of treatment for many persons with ailments. However, it is perplexing that sometimes, even when blood urea is normal, arrhythmia occurs, and what is behind it?
First, sedimentation and dissolution of urea acid crystals is a dynamic process. In the event of ailments, the urea acid crystals are deposited in joints and surrounding tissues. When blood urea levels rise, the crystal is formed more rapidly; and when we reduce blood urea by, for example, drug or dietary control, these deposited urea crystals do not disappear immediately. They continue to exist for a period of time, such as in the joints, and continue to stimulate the surrounding tissue, causing inflammation and arrhythmia. It is like piled up in a room, and even if we stop adding to the room, the groceries that have been stacked there (urealate crystals) may cause confusion (a painful event) by accidentally touching (e.g., minor joint activity, local temperature changes, etc.).
Secondly, the inflammatory state of the body also plays an important role. Periphery itself is an inflammatory disease, and even if haematological urea levels return to normal, within and around the joints may remain in a relatively sensitive state of inflammation. A number of factors, such as infection, trauma, overwork and cold irritation, may lead to an increase in the inflammatory response of the body, which can lead to a resurgence of arrhythmia. For example, when there is a slight trauma to the joint, the body’s immune system quickly initiates an inflammation response to repair the damage, but in the case of pain, the response may be over-activated, leading to a resurgence of acute inflammation around the urea acid crystal, which is otherwise “sleeping”, causing pain.
Furthermore, levels of blood urea acid in humans fluctuate. Although the blood ureal acid values we have detected are within normal range, they may vary in a different period of the day or in certain special circumstances. For example, the failure to refill water in a timely manner after extensive sweating or the ingestion of large amounts of high-heavy food at short notice (even if the overall diet is well controlled, occasional “fluencing”) may result in a short increase in haematic acid levels, which can cause arrhythmia. Such fluctuations may not be readily detectable in conventional blood urea tests, but they do have a real impact on the onset of gout.
Moreover, the effects of drugs cannot be ignored. Some patients may experience a rapid decline in urea acid levels as a result of their mechanisms of operation or individual differences in their use. This dramatic change in the level of urea acid can lead to an increase in the rate of dissolution of the urea acid crystals in the joint, which can also cause inflammation and lead to arrhythmia, which is medically referred to as “solar crystals”.
While normal haematosis is an important indicator of pain treatment, it does not mean that it does not occur. Patients need to maintain a healthy lifestyle, avoid predisposing factors, adhere strictly to medical prescriptions, and regularly review blood-ureic acid and related indicators so that doctors can adjust their treatment programmes in a timely manner. Only through integrated management will it be possible to better control gouts, reduce the number of onsets, improve the quality of life and avoid serious complications such as pain stones and kidney damage.
