The best time for tumour treatment.In everyday life, many patients are believed to have similar questions. What does the first, second and third lines of tumour treatment mean? How? Why is there a difference between guidance recommendations and health care adaptation? So, the first, second and third lines refer to the sequence of all-body treatments after an advanced patient’s diagnosis, but new assistive and assistive treatments for the immediate surgery do not fall within this category.What does one, two, three treatment mean?The concept of the number of lines of treatment for tumours is, in general, a description of the stage of treatment. However, it is premised on the fact that these lines are a whole-of-the-mass anti-tumour treatment in case of non-surgery advanced malignant neoplasms, or re-emergence in the early and medium term.For patients who can be surgically removed in the early and medium term, “new assisted treatment”, “auxiliary treatment”, “surgery”, “local treatment” etc. are used to describe the treatment phase.We can think of a special marathon relay race, which does not set time or distance, with the end being the goal of “cure” — after the first player is exhausted, the second runner continues to run, and so on, until all players are unable to run again or succeed in achieving the cure.In this competition, “players” are all kinds of anti-oncological treatment, and “run time” is the patient’s life. The first, second and third-line treatment is the order in which the players play in the competition. First-line treatment: refers to the second-line treatment of the first-round treatment programme after an advanced diagnosis of cancer: the first-line treatment programme is drug-resistant (disease progress) or the third-line treatment of a different anti-cancer regimen: the second-line treatment programme is also drug-resistant (disease progress) or insufferable replacement of other treatment programmes [1]. With that kind of push. In some cases, all lines after first-line treatment are combined into “second-line treatment and above”.How did the first, second and third-line treatments work out, and how did the order of the players come in? Does it matter who first? Apparently not.First, different players are different, some are weaker, and it is difficult to travel too far, even on a wide road, and can waste valuable time and quality “runway”. Second, patients who have been treated and are making progress are generally in poor health, i.e., the “runway” becomes worse every time a player is replaced.The most rational arrangement, therefore, is to allow the best “sportsmen” to run long and long on the best road conditions, preferably directly to the end of the healing. That’s what doctors always say: “Good medicine first.”Even if it is necessary to change the track and the player midway, at least the total time and distance of the run can be extended as much as possible.Sometimes people wonder if it’s time to leave the best players behind.That’s the way it works. Oncological treatment guidelines recommend one, two, three-line programmes for different types of patients based on the efficacy of the programmes, the adequacy of clinical evidence, etc. As the first-line treatment team, which is said to be “a drum of gas”, is often a more effective, evidence-based programme, and usually the most likely cure.Finally, it also reminds us that there is only one first-line treatment and that maximum benefit should be sought. The development of immunotherapy makes us all the more aware that, while the timing of treatment on tumours is important, it is also important not to rush into the arbitrary replacement of first-line treatment programmes.
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