Within the extended family of antibiotics, Amocilin is undoubtedly well known and widely used as a “star drug”. It has played an important role in the fight against bacterial infections and has saved the lives of countless patients. The following is a detailed presentation of Coop on the Amorim.
I. Origin and development of Amorim
The birth of Amosilin is closely related to penicillin. In 1928, the British bacterologist Fleming discovered penicillin. The emergence of penicillin is a major breakthrough in the medical history, and it offers hope for humans to confront bacterial infections. However, penicillin has some difficulties in extracting and purification, limiting its wide application. Until later, scientists had successfully developed the amocin-based research and refinement. The emergence of Amosilin has not only increased drug stability and oral absorption, but also expanded its antibacterial spectrum to make it a more effective antibiotics.
II. ROLE MECHANISMS
Amosilin is a semi-synthetic β-neamide antibiotics. Its mechanism of action is mainly to inhibit the biosynthesis of bacterial cell walls by combining it with penicillin in bacterial membranes. The cytowall of bacteria is an important structure for its morphology and survival, and the role of Amorim leads to a lack of bacterial cytology, which, after loss of protective protection, swells, deforms and eventually breaks as a result of water infiltration. This unique mechanism of action has resulted in the strong microbicide of the Amosilin to the Geran positive and to some of the Geranne vaginal bacteria.
III. Adaptation
1. Respiratory infections: Amocilin has good treatment for upper respiratory infections caused by pneumonia streptococcus, soluble streptococcus, influenza haemophilus influenzae, such as oscillitis, sinusitis, tonsilitis and lower respiratory infections such as acute bronchitis and pneumonia. Patients often suffer from coughing, coughing, fever, osteoporosis, etc., after infection, and use the Amosilin to effectively kill pathogens, mitigate symptoms and promote recovery.
2. Infection of the urinary genital system: Bacteria, such as intestinal Ethycoccus and fungi, are common pathogens that cause infections of the urinary genital system, such as urinitis, bladderitis, renal diarrheal and cervical infections. Amosilin can quickly kill these infected strains and eliminate symptoms of discomfort such as urination, excrement and urine pain.
3. Skin soft tissue infections: When the skin is traumatized, if it is not cleaned and disinfected, it is easily infected with bacteria such as soluble streptococcus, raiscoccus and coli-eshiccus, which causes skin soft tissue infections such as curvitis, thallium, thorium, and mouth-cutting infections. Amosilin is able to combat these bacteria effectively and to promote healing.
4. Infection of the digestive system: In terms of the digestive system, Amocilin has some therapeutic effect on diseases caused by fungus infection, such as gastrophositis and mestizos. Co-use with other drugs is usually required for the purpose of eradication of the fungus.
5. Other infections: Amosilin can also be used to treat typhoid, other salmonella infections, hook helix, etc.
IV. Usage
Amosilin has a variety of formulations, including tablets, capsules, granules, dry sulfurs, injections, etc. Use of different formulation types varies:
Oral preparations:
• The average adult is 0.5 g per 6-8 hours and does not exceed 4 g per day.
• A daily dose of 20 to 40 mg/kg per day for infants, 1 in 8 hours; an oral dose of 50 mg per day for newborns and premature babies, 1 in 12 hours per day for infants up to 3 months.
Injectives: 1 in 0.5-1g per 6-8 hours for adults; 3-4 times per day for children at 50-100 mg/kg body weight. For patients whose kidney function has been severely impaired, the dose needs to be adjusted to the internal acetic anhydride removal rate.
V. Adverse effects
1. Allergies: This is one of the most common adverse effects of the Amorim. The rash is the most common expression, most of which occurs after seven days of medication, with rashes or rashes, and multiform red spots when serious. In addition, symptoms such as drug fever, asthma and severe allergies can even endanger life. Sensitivity is more likely to occur when patients with infectious mononucleocytes, lymphocyte leukaemia and HIV infections use the Amosilin.
2. Gastrointestinal reaction: More common is the reaction of digestive systems such as nausea, vomiting, diarrhoea and, occasionally, paralytic enteritis. Some of the patients may also have symptoms such as black tongue disease, haemorrhagic intestinal inflammation, and dystrophy, while caramicillin-related enteritis is extremely rare.
Blood system anomalies: occasional decrease in the number of neutral particles, slabs, white cells, increase in the number of acidic particles and increase in the number of patients.
4. Symptoms of the nervous system: Large-dose intravenouss may have neurotoxic symptoms such as convulsions.
5. Dual-infection: The long-term or unreasonable use of Amosicillin may lead to double-infection, such as pyrocolosis or drug-resistant bacteria.
6. Other: Infants may experience an increase in their internal pressure after the application of Amosicillin, in the form of a rise in their ex-fouling; the use of this drug by female patients suffering from severe muscular incapacities may aggravate the symptoms.
VI. NOTES
Pre-medicine testing: Amosilin is a penicillin-type drug with a risk of allergies and therefore must be tested with penicillin-skin sensitivity before it is administered.
2. Avoiding misuse: Amorim is an antibiotic that is effective only for bacterial infections and is ineffective for diseases caused by viral infections, such as common flu, influenza etc. The abuse of antibiotics not only does not treat diseases, but also increases bacterial resistance, making subsequent treatment difficult.
3. Drugs for specific population groups:
• Pregnant women: The United States FDA classification of pregnancy safety in Amosicillin is level B, and the advantages and disadvantages of using medication for pregnant women should be weighed.
Lactating women: Amosilin can be sown in milk, which can lead to a sensitization of infants, and breast-feeding women should stop breastfeeding.
• Older persons: the kidney function of older persons may be reduced and the dose may need to be adjusted when used.
• Incomplete kidney function: Depending on the extent of the kidney function impairment, the period between delivery needs to be adjusted.
4. Drug interaction: The combination of drugs with proposulfosulfon, aspirin, mesmerism, porcelain and sulfamide can reduce the excretion of the amosilin in the kidney tube, increase the concentration, sustain the effects and possibly increase the adverse effects. Co-use with Wafalin enhances the anticondensation effect; co-use with antibacterials such as chlorocin, erythracin, tetracyclics and sulfamide can interfere with the fungicide activity of Amosilin and is therefore inappropriate.
In short, Amocilin is a very important antibiotics, but it must be used in strict compliance with the doctor ‘ s advice, with care and care to ensure safe and effective use.
