Cron disease is a chronic, regenerative, inflammatory intestinal disease, which is exhausting the whole digestive tract from the mouth to the anus, but is mainly good for the end of the intestine and colon. The causes of the disease are not yet fully identified and may be related to the interplay of genetic, environmental, immune and intestinal microecological factors.
I. Clinical performance
Cron’s symptoms are diverse and complex. Common intestinal symptoms include abdominal pain, which is mostly intermittent, situated in the lower right abdomen or umbilical week, and can be of acoustic, corrosive or blunt nature. Diarrhoea is also a prominent manifestation, with an increase in the number of defecations, which can be defecated in paste or rare water, and can be blooded when it is serious. In addition, patients may be accompanied by abdominal buns, enteric infarction symptoms such as nausea, vomiting, abdominal swelling, stop exhausting, etc. In addition to intestinal symptoms, all-body symptoms, such as fever, inefficiency, wasting, anaemia, malnutrition, etc. can be observed, and children may experience stunting. Out-of-intestinal behaviour such as oral ulcer, skin dysentery, arthritis, eye iris, etc. cannot be ignored.
Diagnosis
Because of the lack of specificity in the symptoms of Crohn ‘ s disease, diagnosis often requires a combination of multiple factors. The first is clinical performance and collection of medical history, where doctors ask questions about patients’ symptoms, pathology, family history, etc. Endoscopy is an important tool, such as colonoscopy, small intestinal lenses, etc., which directly observe intestinal mucous membranes, typically in the form of vertical ulcer ulcer, pebble-like appearance, and intestines. Visual screening is essential, including microintestinal imaging, CT intestinal imaging (CTE), MRI intestinal imaging (MRE), etc., and helps to understand the extent, depth and complications of intestinal pathologies. In addition, blood tests are required to detect indicators such as blood routines, blood sank, C reaction proteins, blood clean proteins, to assess the extent of inflammation and the nutritional status of patients, and to conduct excreta tests to remove other intestinal diseases. The pathological biopsy is also critical to the diagnosis, and the pathological analysis of intestinal mucous tissues is used to observe the presence of characterizational pathologies such as swollen gravy.
Treatment
There is currently no cure for Cronn ‘ s disease, but effective treatment improves the quality of life of patients by controlling symptoms, inducing absconding, preventing relapses and preventing complications. Medicine treatment is the primary means, during which amino-hydroxy acid formulations, such as mesalazine, can be used in light patients; for moderate-heavy patients, sugar-coated hormones, such as piston, can rapidly control inflammation, but are not suitable for long-term use because of their side effects; immunosuppressants, such as sulfur and thorium, are often used for hormonal dependent or ineffective patients to maintain mitigation; and biological agents, such as Inflisi monotoxin, have been widely used in recent years, with significant effects on patients with traditional treatments or serious complications, but at relatively high prices. In addition to drug treatment, nutritional support treatment is important, and for those who suffer from malnutrition, sufficient heat, protein, vitamins and minerals can be replenished through intestinal or extraintestinal nutrition, promoting intestinal mucous membrane restoration and improving the nutritional status and immune function of patients. In some cases, serious complications such as intestinal infarction, piercing and haemorrhage may require surgical treatment, but the rate of relapse after treatment is high and after surgery still requires drug maintenance.
Cron disease is a complex disease that has a greater impact on the physical and mental health of patients. Patients should be properly aware of the disease, actively cooperate with doctors in regulating treatment, maintain good living habits and mentalities, and review regularly in order to adjust treatment programmes in a timely manner and effectively control the condition.
