In our abdominal world, this tiny organ of appendix is sometimes “breeding”, causing acute appendicitis and causing us pain and discomfort. While antibacterial drugs play an important role in the treatment of acute appendicitis, there is a great lesson about how to use them rationally. First, let’s find out what acute appendixitis is about. The appendix is a long tubular organ at the end of the appendix, which can cause inflammation when it is blocked, infected or blood-borne. Symptoms of acute appendicitis are usually more visible, such as transferive pain, nausea, vomiting, fever, etc. Once diagnosed, the treatment is rapidly carried out, and antibacterial drugs are often an important component of treatment programmes.
So what is the role of anti-bacterial drugs in the treatment of acute appendicitis? In short, they are like a “fire brigade” designed to put out the “flammation” of inflammation, control bacterial infections, mitigate inflammation and create favourable conditions for self-rehabilitation. However, for this “fire brigade” to work efficiently, rational use of antibacterial drugs is essential. The first step is to select appropriate antibacterial drugs according to the severity of the condition. In the case of simple acute appendicitis, i.e. mild inflammation, no perforation or sepsis, doctors may choose a relatively narrow range of antibacterial drugs, such as first- or second-generation morbid. But if the condition is more serious, such as an appendix puncture, an abscess, or the patient’s own underlying conditions, such as diabetes mellitus, low immune capacity, etc., then a broader combination of antibacterial drugs, such as third-generation cystasy and lysergium, may even require joint use of other types of antibacterial drugs.
Once the type of antibacterial drug has been identified, the next consideration is the dose and course of treatment. Insufficient doses are too weak to effectively control the fire, and excessive doses can cause unnecessary side effects and damage to the body. In general, the doctor calculates the appropriate dose based on the age, weight, liver and kidney function of the patient. The length of treatment depends on the recovery. As a rule, antibacterial treatment for simple acute appendicitis may last 3 to 5 days, but if the condition is complex, the treatment may be extended to 5 to 7 days or more.
Special populations need to be more cautious when using antibacterial drugs to treat acute appendixitis. For example, children ‘ s bodies are still developing, organs are not yet mature, and the metabolism and resistance to microbacterials are different from those of adults. Thus, when choosing anti-bacterial drugs for children, doctors take into account the safety and effectiveness of drugs and may adjust their types, doses and methods of use. For older persons, as a result of their reduced physical functioning, the liver and kidney function may be inferior to that of young people, as will the metabolic and excretion capacity of anti-bacterial drugs. As a result, the liver and kidney function is closely monitored by the doctor during the use of the drug in order to avoid adverse effects due to its accumulation in the body. Pregnant women are also a special group because of the presence of the foetus and the more stringent choice of anti-bacterial drugs. Certain antibacterial drugs may have adverse effects on the foetus, so doctors weigh the advantages and disadvantages, choose the drugs that are relatively safe for pregnant women and the foetus, and closely monitor the foetus during treatment.
In addition, anti-bacterial drugs are used over time. Premature use may conceal the condition and affect the doctor ‘ s diagnosis; late use may lead to the spread of inflammation and increase the condition. In general, after the acute appendicitis has been diagnosed and if a decision is made to provide a first conservative treatment, an antibacterial drug is given by the doctor as soon as possible. However, if the condition is moving rapidly, or if the symptoms are not improved or even aggravated after conservative treatment, there may be a need for timely surgical treatment and end-of-service. Attention also needs to be paid to the interaction of drugs in the use of anti-bacterial drugs. Some drugs may affect the absorption, metabolic or therapeutic effects of anti-bacterial drugs, such as some anti-acid drugs, which may reduce blood concentrations in some anti-bacterial drugs, thus affecting treatment outcomes. Therefore, patients who use anti-bacterial drugs must be informed by the doctor if other drugs are needed, so that the doctor can make reasonable adjustments.
Finally, the cooperation of the patients themselves is very important. During the use of anti-bacterial drugs, the medication is to be taken on time, as prescribed by the doctor, and does not increase or eliminate the dose. At the same time, care should be taken to observe signs of change in the body and to inform the doctor in a timely manner if there are adverse reactions such as allergies, gastrointestinal discomfort, etc. In short, the rational use of antibacterial drugs is one of the keys to the treatment of acute appendixitis. Through the professional judgement of doctors and the active cooperation of patients, we are able to fully utilize anti-bacterial drugs, effectively control inflammations and help patients to recover their health as soon as possible.