Whether
breast cancer patients can be targeted therapy depends on the molecular classification of breast cancer. For patients with HER-2 positive breast cancer, this is the primary population for targeted therapy. HER-2 (human epidermal growth factor receptor-2) is a proto-oncogene that is overexpressed or amplified in about 15-20% of breast cancer patients. When HER-2 is positive, anti-HER-2 targeted drugs, such as trastuzumab, pertuzumab, lapatinib and neratinib, can be used. These drugs can precisely act on HER-2 targets and block the growth signal transduction pathway of cancer cells, thus inhibiting the proliferation of cancer cells, reducing the risk of recurrence and improving the survival rate of patients. In addition, for patients with triple-negative breast cancer, although there is no clear single target like HER-2 positive breast cancer, there are also some new targeted therapy studies under way. For example, some suitable triple-negative breast cancer patients may also benefit from drug research targeting androgen receptor (AR) and PI3K-AKT-mTOR pathway. Breast cancer patients should pay attention to balanced nutrition and reduce adverse reactions during targeted therapy. First of all, ensure adequate protein intake. You can eat more lean meat, such as chicken and beef, as well as high-quality protein foods such as fish, shrimp and eggs, which help to maintain the normal physiological function and tissue repair of the body, because targeted therapy may have a certain impact on body tissues. Secondly, we should eat more vegetables and fruits. Vegetables such as spinach and carrots are rich in vitamins and minerals, which help boost the body’s resistance. Fruits such as apples and strawberries are rich in antioxidants such as vitamin C and flavonoids, which help reduce the damage caused by the side effects of drugs. Whole grains, such as oats and whole wheat bread, are also good choices. They are rich in dietary fiber, which helps intestinal health and reduces constipation. Because some targeted drugs may affect intestinal function. In terms of cooking methods, it is recommended to give priority to steaming and stewing, so as to retain the nutrients of food to the greatest extent. For example, you can choose steamed fish, boiled eggs and so on. In addition, because targeted therapy may cause gastrointestinal discomfort, we should avoid eating spicy, greasy, stimulating food, such as chili, fried food and so on. At the same time, we should reduce the intake of high-sugar foods, because this may increase the burden on the body, which is not conducive to blood sugar control. If the patient has edema and other conditions, it is also necessary to control salt intake.
