Levofloxacin is a wide spectrum antibacterial drug, which is an antibiotic of fluorophenone, and is widely used for the treatment of multiple bacterial infections because of its high-efficiency antibacterial activity and good tissue penetration. Details will be provided in this paper on the pharmacological effects of the left oxen salsa, adaptability, usage, adverse effects and care.
I. Pharmacological effects of the left oxyfluorosalt
The left-rotary isomer of fluorooctanone-antibiotic oxyfloxone, which is twice as active as oxyfluorosalt. Its main mechanism of action is to prevent the reproduction and transfer of bacterial DNA by inhibiting bacterial DNA rotor enzymes (DNA gyrase) and expanding isomerase IV. Left oxen fluoride is a good antibacterial activity for gerrand positive bacteria, gerrand vaginal bacteria and some atypical pathogens (e.g., chlamydia, chlamydia).
(i) Antibacterial spectra
1. Genran cactus: e.g. coli, creber, cyanobacteria, haemophilus influenzae, etc.
2. Geran positive fungi: e.g., golden septococcus (including partially methooxic septococcus), pneumococcus, etc.
3. Atypical pathogens: e.g., chlamydia, chlamydia, legions, etc.
4. Other pathogens: e.g., fungi and certain anaerobic bacteria.
II. Adaptive symptoms of the left oxyflour
Left oxen fluoride is used to treat a wide range of infectious diseases caused by sensitive bacteria, including the following:
(i) Respiratory infections
1. Community access to pneumonia (CAP): for example, pneumonia caused by streptococcus, influenza haemophilus influenzae or paragenes.
2. Acute intensification of chronic bronchitis: acute outbreak of chronic bronchitis caused by bacterial infections.
(ii) Utility system infections
Acute pure urinary tract infections: e.g. bladderitis caused by coliform.
Complex urinary tract infections: including kidney diarrhea, etc.
(iii) Skin and soft tissue infections
e.g. beeweaves, swollen swollen, etc. caused by yellow grapes or strep.
(iv) Gastrointestinal infections
For example, bacterial intestinal inflammation caused by salmonella, Shiga or Bacillus.
(v) Other infections
1. Bones and joint infections: for example, osteoporosis caused by sensitive bacteria.
Eye infections, such as bacterial conjunctivitis (for local eye drops).
Cervical infections: for example, peritoneumitis caused by the geran vaginal bacteria.
III. Usage and usage of left oxyflour
Left oxyfloxa may be administered by oral or intravenous injection, and the dose and course of treatment should be adjusted to the type of infection, severity and kidney function of the patient.
(i) Regular adult dose
1. Respiratory infections:
Community access to pneumonia: 500 mg per day for 7-14 days.
Acute increase in chronic bronchitis: 500 mg per day and 7 days of treatment.
2. Utility system infections:
Acute pure urinary tract infections: 250 mg per day, 3 days of treatment.
Complex urinary infections or renal inflammation: 500 mg per day, 7-10 days of treatment.
3. Skin and soft tissue infections:
500 mg, 1 session per day, 7-14 days of treatment.
4. Gastrointestinal infections:
500 mg, 1 session per day for 3-5 days.
(ii) Dose adjustments for special population groups
1. Patients with incomplete kidney function:
acetic anhydride removal rate of 30-50 mL/min: first dose of 500 mg, followed by 250-500 mg per 48 hours.
<30 mL/min: First dose of 500 mg, then 250 mg per 48 hours.
2. Older patients:
The elderly patients need to adjust the dose to the kidney function to avoid accumulation.
(iii) Method of delivery
Oral: The left oxen fluoride tablet shall be swallowed as a whole and shall not be taken at the same time as a drug containing calcium, magnesium, aluminium and iron (e.g. anti-acid agent) in order not to affect absorption.
2. Injection: An intravenous drip should take not less than 60 minutes to reduce the occurrence of adverse effects.
IV. Negative reaction of left oxyfloxa
Despite the good antibacterial activity of the left oxen fluoride, its use may be accompanied by some adverse reactions that require attention.
(i) Common adverse effects
1. Gastrointestinal responses: such as nausea, vomiting, diarrhoea, abdominal pain, etc.
2. Central nervous system response: headaches, dizziness, insomnia, anxiety, etc.
3. Skin reactions: e.g. rash, itch, photo-sensitive.
(ii) Unusual but serious adverse effects
1. muscular hysteria: This includes mystic inflammation and fissure, especially among elderly patients or those who use co-synthesis.
2. QT inter-temporal extension: may cause cardiac disorders and need to be carefully applied to patients with a history of heart disease.
3. Allergies: for example, severe allergic shock or Stevens-Johnson syndrome.
4. Hepatic function impairment: e.g. hepatic enzyme rise or pharmaceutical hepatitis.
V. Attention on the use of left oxen fluorine
(i) The taboo
1. Prohibition of allergies of left-oxen fluorine or other quinone-type drugs.
2. Prohibition of use by pregnant women, nursing mothers and children under 18 years of age (because of the possible impact on cartilage development).
(ii) Discretion
1. Older patients: The reduction in kidney function requires a dose adjustment to avoid drug accumulation.
Epilepsy patients: Left oxen fluoride may lower the threshold for epilepsy and should be used with caution.
3. Heart disease patients: People with an extended QT period or a history of heart disorder need to be used with caution.
(iii) Drug interaction
Anti-acidants: Anti-acidants with aluminium, magnesium and calcium reduce the absorption of left oxyfluorosatron and should be taken at intervals of two hours.
2. Wafarin: The co-location with the left oxidoxen salsa may increase the risk of haemorrhage, and condensation should be monitored.
Sugar cortex hormones: co-use may increase the risk of muscular disease.
(iv) Other matters of concern
1. Avoiding exposure to strong light to reduce the occurrence of light-sensitive reactions.
2. More drinking water should be provided during the use of the drug in order to facilitate its discharge and reduce the risk of renal toxicity.
Concluding remarks
Left oxyfloxa, as a wide spectrum antibacterial drug, plays an important role in the treatment of a wide range of bacterial infectious diseases. However, their use requires strict adherence to medical prescriptions, reasonable choice of dose and course of treatment, and avoidance of abuse or misuse to reduce resistance and adverse reactions. Patients should be aware of the taboos and precautions of the drug when using the left oxen fluoride and should be treated in a timely manner in the event of serious adverse reactions. Through scientifically sound use, left-oxen salsa can effectively control the infection and promote the rehabilitation of patients.
