Antibacterials of sugar platinum: use and attention.

Among the extended families of antibacterials, antibacterials of sugar platinum play an important role, like “hard weapons” against drug-resistant bacteria, and play a key role in the treatment of multiple serious infections. However, such drugs are used in many ways, with a proper understanding of their daily use and care, both to ensure their effectiveness and to minimize the occurrence of adverse effects.First, the mechanism for the functioning and scope of application of antibacterials of sugar peptide are mainly antibacterial by inhibiting the synthesis of bacterial cell walls. They have a strong antibacterial activity for gland positives, particularly for methoxicillin resistance, and for skin and intestinal fungi. Often used for the treatment of serious infections caused by these drug-resistant bacteria, such as sepsis, meningitis, osteoporosis and pneumonia. In clinical terms, doctors tend to consider the use of glycol antibacterials when the patient is suspected or diagnosed with the above-mentioned antibacterial infections and other antibacterial treatments are ineffective or not applicable.The daily use of common glycol antibacterials is FVC: the traditional use of VC is usually intravenous dripping. The average adult received a daily dose of 2g, which can be divided into 2-4 times. For severely infected patients, the dose may increase appropriately. In the case of intravenous dripping, attention needs to be paid to the concentration and rate of the drug. Drugs are usually required to be at concentrations not exceeding 5 mg/ml and not less than 60 minutes in order to reduce the occurrence of adverse reactions such as the Red Man Syndrome. In recent years, as studies on the pharmaceutical dynamics and Pharmacology of Vancoma have advanced, individualization based on blood concentration monitoring has also been promoted to ensure that the drug reaches both effective antibacterial concentrations in the body and is not toxic due to high concentrations. Demethylvancin: It is used in a manner similar to that of vancin, with an adult daily dose of 0.8 – 1.6 g and 2 – 4 intravenous drops. Similarly, attention needs to be paid to the control of drip concentrations and speeds in order to ensure the safety of medicines.For Kaolanin: The treatment for Kaolanin is relatively flexible. It can be given a load dose of 400 mg (6 mg/kg), usually once every 12 hours, three consecutive times, followed by a maintenance dose of 400 mg (6 mg/kg), usually once a day. The daily delivery programme can also be used directly for patients with mild infections. Muscle injections are also available for Kaulanning, but the potential for local pain and condensation may result in the clinical use of intravenous drugs. Drug concentrations do not normally exceed 10 mg/ml at the time of intravenous dripping, for a period of not less than 30 minutes.III. Mind-breeding allergies in the use of pelican antibacterials: Pelican antibacterials may cause allergies, including rashes, itching, measles, fever, etc. Before using drugs, doctors are required to enquire in detail about patients ‘ allergies, particularly with regard to other antibacterial drugs or drug supplements. If the patient has a history of sensitivity, it should be used with caution and the reaction of the drug is closely observed. In case of allergies, the drugs should be stopped and the corresponding allergies treated.Kidney toxicity: This is one of the more prominent adverse effects of antibacterial sugar platinum. The general renal toxicity rate is relatively low for patients with normal kidney function, but the risk of renal toxicity increases significantly for patients with incomplete kidney function. Thus, the kidney function indicators of patients, e.g., blood acetic anhydride, urea nitrogen, etc., need to be closely monitored before and during drug use. If an abnormal renal function is detected, the dose of the drug or a stop drug should be adjusted in a timely manner and appropriate treatment should be taken in accordance with the extent of the kidney function impairment. At the same time, joint use with other renal toxic drugs, such as amino sugar antibacterials, is avoided to reduce the risk of kidney damage.Ear toxicity: Although the incidence of Ear toxicity due to antibacterial glycols is relatively low, it should not be overlooked. Ear toxicity is manifested mainly in hearing loss, ringing, etc., and may lead to permanent deafening in serious cases. Particularly for the elderly, children and patients who use other ear-toxic substances (e.g. lysers) at the same time, there is a greater need to pay close attention to hearing changes. During the use of the drug, hearing checks can be conducted on a regular basis and should be stopped and evaluated and processed in a timely manner in the event of hearing abnormalities.Red Man Syndrome: This is a more common adverse reaction of vancocin, mainly due to the release of groupamine when drugs are rapidly dripped. Patients can have symptoms such as facial, neck, upper skin red, itch, blood pressure drops, severe respiratory difficulties, cardiac arrest, etc. In order to prevent the occurrence of a red human syndrome, the drop speed should be strictly controlled when venomous drops of Vungucin occur, so that the drug is slowly entering the body. In the event of symptoms of a red human syndrome, the dripping should be stopped immediately, and treatment should be provided for such symptoms as anti-montamine drugs. It is generally possible to slow down the drop-down rate and continue to use the drug after the symptoms have abated.Drug interactions: There may be interactions between pep and other drugs. For example, when used in combination with amino-succused antibacterials, the risk of renal and ear toxicity may increase; when used in combination with anticondensed drugs such as Wafalin, it may affect metabolism of anticondensatives and lead to abnormally coagulation functions. Therefore, when using antibacterial glycols, doctors should be informed of other drugs that are being used by patients, so that doctors can assess the risks of drug interaction and adjust the drug programme.Drugs for specific groups: For special groups such as the elderly, children, pregnant women and lactating women, greater care needs to be taken in the use of antibacterials such as sepsis. The resistance of older persons to drugs is reduced as a result of physiological changes, such as reduced kidney function, and the dose may require appropriate adjustment. Drug metabolic and excretion functions for children are not yet fully developed and dosages should be calculated accurately on the basis of age, weight, etc. The use by pregnant and lactating women of antibacterial sugar can have a negative impact on the foetus or on the baby, and only when it is clear that the benefit of the drug outweighs the risk is carefully used, under close medical supervision. Antibacterial sugar platinum-type drugs are important drugs for the treatment of drug-resistant gebrane-positive infections, but in their use they need to be strictly followed in terms of usage, with close attention to the concerns. When using such drugs, patients should actively cooperate with the doctor ‘ s treatment and inform him/her of his/her state of health and of his/her history, so that the doctor can develop a personalized treatment programme. At the same time, medical doctors should be provided with timely feedback in case of any symptoms of discomfort during the use of the drug in order to be able to deal with it in a timely manner and to ensure that it is safe and effective.