A brief introduction to antibacterial drugs.
In the medical field, antibacterial drugs have always played an essential role. Since penicillin was discovered and used in clinical treatment, antibacterial drugs have opened a new era of human and bacterial infection resistance. Anti-bacterial drugs are, in short, a class of drugs that can suppress or destroy micro-organisms such as bacteria. Their emergence has significantly reduced the high mortality rate that has been caused by bacterial infections and has transformed many serious infectious diseases from deadly threats to curable diseases. Whether it is common respiratory infections, urology infections, life-threatening sepsis, meningitis, etc., antibacterial drugs come out at a critical time to protect the health of patients.
However, with the widespread use of antibacterial drugs and the evolution of bacteria, the problem of drug resistant bacteria has become more and more acute. The fact that antibacterial drugs, which have had special effects, may not be able to cope with certain strains of resistant bacteria today not only poses enormous challenges to clinical treatment, but also warns of the urgency of rational use of antibacterial drugs. Proper knowledge and understanding of anti-bacterial drugs, including their type, mechanism of action, scope of application and use of care, are of paramount importance, both for the medical profession ‘ s precision and for the general public ‘ s proper treatment of infectious diseases. It is about the improvement of medical performance and is more about the human race’s triumphs and failures in this long-lasting “war” with bacteria. I will talk about my feelings from the following points:
I. Basic concepts of antibacterial drugs
The first knowledge of so-called anti-bacterial drugs is, by definition, those that are fungicidal or anti-bacterial. These include both certain products produced by microorganisms such as bacteria, wired bacteria and fungi, such as antibiotics, as well as the same or similar substances manufactured through chemical synthesis, such as sulfamide, americ acid, nitromite and quinone. At a certain concentration, they inhibit and kill pathogens and are essential drugs for clinical treatment.
Classification of antibacterial drugs
The second is the variety of antibacterial drugs, which, depending on their chemical structure and functioning mechanisms, can be grouped into the following broad categories:
a. Beta-neamide: This is the most important category of antibacterial drugs, including penicillin, septactin, carbon cyanide, etc. They perform microbicide by inhibiting the synthesis of bacterial cell walls.
b. Amino sugar slurry: This drug has a good fungicide effect on e.g. Quintaacin, Tobcin, etc. Their function is to interfere with the synthesis of bacterial proteins.
c. Great mercuric esters, including erythrin, achromicin, etc., are used mainly for the treatment of respiratory, skin soft tissue infections, especially those caused by the styrene, chlamydia and legionella.
d. Four cyclic groups, such as Minocrin, Dossi cycline, etc., with wide spectrum resistance to bacterial activity and sensitivity to lektics, trigens, etc.
III. Mechanisms for the functioning of anti-bacterial drugs
Antibacterial drugs play a variety of roles, including the following:
a. Obstruction of the synthesis of bacterial cytowalls: e.g. penicillin and head sap antibiotics, which kill bacteria by inhibiting the activity of bacterial cyto-synthetic enzymes, resulting in the loss of bacterial cytowalls and thus the loss of protective barriers.
b. Effecting cyto-membrane permeability: e.g., polyazole and polyolefin antibiotics, which can destroy the integrity of the bacterial cellular membrane and lead to the release of bacterial internal material, thereby killing bacteria.
c. Inhibition of protein synthesis: e.g. amino sugar slurry and macrocycline antibiotics, which inhibit the synthesis of bacterial proteins by disrupting the function of bacterial nuclei, thus rendering the bacteria incapable of survival.
d. Depression of nucleic acid synthesis: antibacterial drugs such as quinone and lephoscin, which, by inhibiting the synthesis of bacterial DNA or RNA, interrupt the transmission of genetic information on bacteria for the purpose of microbicide.
IV. Clinical application of antibacterial drugs
Antibacterial drugs have a wide application value in clinical applications. They can be used to treat bacterial infectious diseases such as respiratory infections, urinary infections, skin soft tissue infections, etc. However, the use of antibacterial drugs must be guided by certain principles, such as the selection of appropriate antibacterial drugs according to the type of fungi and the results of drug-sensitive tests; the determination of the dose and course of treatment according to the severity of the disease and individual patient; and the avoidance of unnecessary combinations and abuse of antibacterial drugs.
In addition, antibacterial drugs may have adverse effects during their use, such as allergies, damage to liver and kidney function. Therefore, in the use of anti-bacterial drugs, changes in the patient ‘ s condition must be closely monitored and the programme adjusted in a timely manner to ensure the patient ‘ s safety.
In sum, antibacterial drugs serve as a double-edged sword in the medical field, building a strong fort for human health and ingraining crises with unreasonable use. We must be deeply aware that the rational application of anti-bacterial drugs is by no means the sole responsibility of medical professionals, but requires the active involvement and cooperation of the general public. Every unnecessary use of antibacterial drugs can contribute to the growth and spread of drug-resistant bacteria in the intangibles, ultimately placing us in a drug-free situation in the face of infection. Medical practitioners should at all times adhere to the principle of rational use of medicines, tailor the best antibacterial treatments to patients on the basis of accurate diagnosis and extensive clinical experience, and spare no effort to make the correct use available to patients. The people themselves must be made aware of the need to protect themselves, not blindly and on their own, to use anti-bacterial drugs, to follow medical instructions and to use them on time, on the same scale and according to the procedure.
It is only by working together, together with the medical and medical communities, to create a good climate for scientifically rational use of anti-bacterial drugs that they will continue to lighten human health in the future, effectively curb the spread of resistant bacteria, ensure that we remain active in our long struggle against bacteria, preserve precious medical resources for future generations and maintain a stable foundation of global public health security.
