In the field of treatment of rheumatism arthritis, hormonal treatment is a commonly used but controversial tool with distinct advantages and unmindable disadvantages.
The benefits of hormone treatment are significant. First, strong anti-inflammation and immunosuppression are important underpinnings for hormone applications. The core pathological mechanism for rheumatological arthritis is chronic inflammation of the joints, hormonals rapidly inhibiting inflammatory cell activity and reducing the release of inflammatory media such as prostate, white tritene, etc., thereby rapidly mitigating symptoms such as red swollen fever of the joints. During the acute onset of the disease, when the patient suffers from severe cortex pain, swelling or even restriction of his/her activity and is unable to live a normal life, hormonals can play a role in a short period of time to effectively alleviate the patient ‘ s suffering, e.g., sugary cortex hormones, such as Poneysson, can significantly improve the performance of arthritis for hours to days after the drug is administered, and to win a window of time for the patient to alleviate his/her condition. Second, hormones can work in tandem with other rheumatological drugs. In the treatment programme for rheumatism arthritis, the joint use of anti-heat drugs (DMARDs), hormones can be used for rapid control of inflammation in the early stages of treatment, and to buy time for the role of DMARDs, with the gradual reduction of hormonal use following the gradual effect of DMARDs. This joint treatment strategy helps to improve overall treatment, better control the progress of the disease and improve the functioning of the joint function and the quality of life of the patient.
However, hormonal treatment of rheumatism arthritis has many shortcomings. The first is the multiplicity of adverse effects, and the long-term or large-dose use of hormones can cause a range of serious health problems. In terms of metabolism, hormones can lead to increased blood sugar, increased risk of diabetes, and can affect fat metabolism, re-distribution of fats and the appearance of eccentric obesity in particular forms, such as full moon faces and buffalo backs, as well as increased protein decomposition metabolisms, resulting in muscle atrophy, skin thinness and osteoporosis, which seriously affect the physical appearance and bone health of patients. In the digestive system, hormones stimulate gastric acid and gastric protein enzymes, disrupt gastric mucous barriers and increase the risk of stomach ulcer, stomach haemorrhage and even stomach perforation. In addition, hormones have adverse effects on cardiovascular systems, such as increased blood pressure, sodium retention, increased heart burden and induced cardiovascular disease. Second, hormonal use is at risk of dependency and withdrawal. After long-term hormonal application, the body is subject to adaptive changes, which can lead to retrenchment, increased cortex symptoms and even loss of adrenal cortex function, in the form of nausea, vomiting, inactivity, low blood pressure, etc., which can seriously endanger life. The hormonal detoxification process therefore requires close monitoring of the patient ‘ s medical condition and physical response, under the strict guidance of a doctor and in accordance with the principle of slow reduction.
Hormonal treatment is a double-edged sword for people with rheumatological arthritis. In clinical applications, doctors have to weigh their pros and cons and make careful decisions. In cases of severe acute onset, short-term, small-dose hormones can be used to mitigate symptoms quickly, with strict control of adaptive conditions, combined with other anti-rue-wet drugs, with close attention to the occurrence of adverse reactions and enhanced preventive measures. As the condition stabilizes, hormonal use should be gradually reduced until it is discontinued, the risks associated with hormonal treatment should be minimized, the potential harm to health should be minimized while people receive treatment benefits, and the safe, effective and individualized treatment of rheumatological arthritis should be achieved.
