In today ‘ s rapidly changing medical technology, there has been a marked improvement in the survival and quality of life of people with urinary poisoning. However, a often neglected but very serious complication — the brain disease of urinary poisoning — is a hidden threat to the health of patients. As a medical practitioner, I would like this general science article to provide a clearer understanding of the encephalopathy of urine, its clinical performance, the mechanisms for its occurrence and the treatment of it.
– What’s urine?
Brain diseases of urine poisoning, medically referred to as renal cerebral diseases, are one of the central nervous system complications that can occur in the course of a urinary poisoning patient. In short, it is the accumulation of toxins in the body as a result of urea poisoning that damage the brain and cause a series of neuropsychiatric symptoms. The end-stage of chronic kidney failure is characterized by urea poisoning, with almost total loss of kidney function of the patient and no effective removal of metabolic waste and toxins from the body. These toxins accumulate in the body and may eventually enter the brain through a blood-brain barrier, causing damage to brain cells, leading to urine poisoning.
II. What are the clinical manifestations of urine poisoning brain disease?
Clinical manifestations of urea encephalopathy can range from mental, neurological and motor. The following are common symptoms:
1. Mental abnormalities: this is the early manifestation of urea-toxic brain disease, and patients may experience symptoms such as retardation, insomnia, insomnia, depression, memory loss. As the disease increases, the patient may gradually become unconscious, hallucinating, excited, epilepsy and even unconscious.
2. Neural system disorders: Patients may experience early symptoms such as pronunciation difficulties, tremors, etc. At the end of the day, there may be serious cases of twitching of hands and feet and muscle spasms.
3. Motivation anomalies: People with urea-toxic cerebral disorders tend to be characterized by a lack of mobility, e.g., a lack of movement, or a lack of movement at the end of a fine operation. In addition, patients may have symptoms of local motor nervous impairment such as paraplegic paralysis. These symptoms not only seriously affect the quality of life of patients but may also endanger their lives. As a result, as soon as a person with urinary poisoning is found to have the symptoms described above, he/she should be referred to the hospital for early diagnosis and treatment.
III. What are the basic mechanisms for the occurrence of cerebropathy due to urine poisoning?
The mechanism for the incidence of ureaemia is not yet entirely clear, but is generally considered to be relevant to:
1. The accumulation of toxins: the accumulation of metabolic waste and toxins in patients with urine poisoning is the main cause of cerebropathy of urine poisoning. These include small molecular toxins such as urea, acetic anhydride, urea acid and gills, as well as large molecular substances such as thyroid pertininin and beta-microprotein. These toxins may cause direct damage to brain cells when they enter the brain through a blood and brain barrier.
2. Energy metabolic anomalies: Cell breathing and glucose fermentation in patients with urine poisoning are inhibited, preventing cells from generating enough energy to maintain normal functions. This energy metabolic anomaly may further exacerbate brain cell damage.
3. Electrolytic disorders and acid alkali balance disorders: People with urinary problems are often associated with electrolytic disorders and acid alkali alkali equilibria, such as high potassium haematosis and metabolic acid poisoning. These disorders can interfere with the normal physiological functioning of brain cells, leading to urea poisoning.
4. Neurotransmitters: The blood and brain barriers of patients with urea poisoning have been damaged, certain organic acids can enter the brain tissue, disrupt the conversion of neurotransmitters and lead to neurotransmitters. This imbalance may cause neurosis, which in turn exacerbates the condition of urinary-toxic brain disease.
IV. What should be done with the encephalopathy?
The treatment of encephalopathy requires a combination of the specific circumstances of the patient and individualized treatment programmes. The following are common treatments:
1. Adequate dialysis: dialysis is one of the important tools for the treatment of encephalopathy. By dialysis, metabolic waste and toxins in the body can be removed and the burden on the brain reduced. Common dialysis methods include blood dialysis, peritoneal dialysis, etc. For people with urea dialysis, adequate dialysis can significantly improve the symptoms and quality of life.
2. Drug treatment: The treatment can be done with appropriate medication for the different symptoms of persons with ureaemia. For example, psychosomatic disorders such as hallucinations, excitement, etc. can be treated with tranquillizers such as fluorol, and epilepsy drugs such as diazine can be controlled with epilepsy. It needs to be noted, however, that drug treatment should be conducted under the guidance of a doctor and that drug side effects and drug interactions should be avoided.
3. Nutritional support: People with ureaemia are often associated with malnutrition and electrolytic disorders. Therefore, in the treatment process, emphasis should be placed on nutritional support to ensure that patients receive sufficient nutrients and electrolyte. Ingestion of high phosphorous food should also be avoided to reduce the kidney burden.
4. Renal transplantation: For persons with ureaemia, kidney transplantation is a treatment that addresses the root causes. Successful kidney transplants can restore the kidney function of the patient, thereby eliminating the causes of urea poisoning. However, kidney transplants are at a higher risk and require appropriate kidney sources and long-term immunosuppressive treatment. Therefore, when choosing the kidney transplant treatment, due consideration should be given to the specific circumstances of the patient and the risk of surgery.
In short, the encephalopathy of urine is a serious complication that requires our utmost attention. By understanding their clinical performance, the mechanisms of morbidity and treatment, we can better prevent and treat the disease and bring better treatment and quality of life to patients. It also reminds the general population and their families of the need for immediate medical attention and treatment in cases of abnormal manifestations of neurological and psychiatric symptoms.
