The ulcer colonitis is a chronic, non-specific intestinal disease with unknown causes, with major heaviness and rectal and colon mucous membranes and mucous membranes, with a continuous distribution of diseases, starting mostly with the rectum and developing back to the immediate end.
Typical symptoms include diarrhoea, mucous sepsis and abdominal pain. Diarrhoea is disproportionately severe, with daily defecation of up to 2 – 4 times per day and heavy of up to 10 times per day. The faeces are often mucous sepsis due to an increase in haemorrhage and mucous ulcer due to intestinal mucemia, curvature and ulcer. The abdominal pains are mostly those of the lower left or lower abdominal pains, as well as those of the whole abdominal pains, often accompanied by a sense of ulterior stress, i.e. that after defecation there is still convenience, but without excrement or only a small amount of mucous sepsis. In addition to intestinal symptoms, the patient may have a number of overall symptoms, such as fever, inactivity, wasting, anaemia, etc., which are more common among those with more serious or chronic conditions. The fever is usually low to moderate, and in case of high fever, it may indicate rapid progress or complications. Chronic diarrhea, defecation and poor nutritional intake can lead to a decrease in the body weight of patients, anaemia and indigence, which seriously affects their quality of life and health.
The causes of ulcer colonitis, which are currently not fully known, may be the result of a combination of environmental, genetic, intestinal microecological and immune factors. Among environmental factors, diet, smoking, sanitation, etc. may be associated with morbidity. For example, chronic high sugar, high fat, high protein diets and Westernized lifestyles may increase the risk of disease. Genetic factors play an important role in the incidence of ulcer colonitis, with relatively high rates of ulcer colonitis in families, and studies have found that several genetic locations are associated with the susceptibility of the disease. Micro-ecological imbalances in the intestinal tract are also an important factor, with a large number of micro-organisms in the intestinal tract normally present, subject to each other, interdependent and maintaining the ecological balance of the intestinal tract. When this balance is broken, e.g. due to infection, inappropriate use of antibiotics, harmful bacteria are overgrowing and may cause intestinal immunisation and inflammation. Immunisation anomalies are at the heart of the ulcer colonitis outbreak mechanism, and the body ‘ s immune system wrongly attacks its own intestinal mucous tissue, leading to a continuous inflammation response, inflammation of inflammation cells, the release of cytological factors, further damage to the intestinal mucous membrane and the formation of a vicious circle.
Diagnosis of ulcer colonitis is based on clinical performance, colonoscopy, pathological biopsies and other ancillary examinations. The colonoscopy is a key means of diagnosis and directly observes the pathology of the colon mucous membranes, typical of mucous membranes, oedema, ulcer formation, continuous and pervading distribution, starting from the rectum and gradually spreading to the near end of the colon. The pathological biopsy is able to specify the nature of the pathological changes, showing a large number of inflammational changes in the mucous membranes and the lower membranes, such as inflammation, inflammation and oscillation, while other intestinal diseases, such as colon tumours and infectious colonitis, are excluded. In addition, blood tests reveal abnormalities in inflammation indicators such as increased white cell count, reduced haemoglobin, increased blood sanctuation and C reaction to protein rise; excreta examinations are used primarily to remove intestinal infectious diseases such as bacteria, parasites, etc.
The treatment of ulcer colonitis aims to induce and sustain clinical decomposition, promote mucous membrane healing, prevent complications, improve the quality of life of patients and minimize relapse. Treatment consists mainly of medication, surgical treatment and nutritional support treatment. Drug treatment is the primary means of treatment, with different drugs being chosen depending on the severity of the condition and the duration of the activity and the relief period. Amino-water canyon acid formulations are common drugs for mild and moderate ulcers, such as nitrous sulfur, mesala, etc., which inhibit intestinal inflammation and reduce symptoms. In case of medium-heavy patients or amino-hydro acid formulations that are ineffective, sugar cortex hormones, such as pennithone, hydrolytic pine, etc., can be used to control inflammation quickly, but sugar cortex hormones are not suitable for long-term use. Immunosuppressants, such as sulfur, cyclists, etc., can be used for hormonal-dependent or ineffective patients to maintain ablution by regulating the immune function. In recent years, biological agents, such as Influenza Monocrotomy, have achieved significant therapeutic effects in the treatment of ulcer colonitis, which can specifically disrupt the effects of inflammatory factors and effectively induce and sustain mitigation. Surgical treatment is applied mainly in serious cases of haemorrhaging, perforation, cancer transformation, and ineffectiveness of hysterectomy, with the general use of whole-circumectectomy to remove intestinal fistula or reintestinal bag acoustic compatibility. Nutritional support treatment is also important for improving the nutritional status of patients and for enhancing their physical resistance, and patients should be guided by the principles of high heat, high protein, low slag diets and, if necessary, supplementing nutrients with nasal or gastrointestinal nutrients.
The ulcer colonitis is a chronic and recurrent disease requiring long-term treatment and follow-up. In daily life, patients should be careful to rest, avoid overwork and stress and maintain a good mentality; stop smoking and alcohol; and avoid eating foods such as irritating foods and dairy products (some patients may be intolerant of dairy products), which may induce or aggravate the disease. Through comprehensive treatment and self-management, most patients are able to control their condition and lead a normal life, but there is still a need to pay close attention to changes in the condition and to regularly review examinations such as colonoscopy so that treatment programmes can be adjusted in a timely manner.
