Parkinson’s Disease: The Neural Secrets and Life Challenges Behind the Fist
Parkinson’s disease, also known as tremors, is a common disease of the mid- and mid-age nervous system. This is mainly due to the degenerative death of neural neurons in the brain, leading to a significant decrease in the dopamine content of the tattoo, which gives rise to a range of motor and non-motor symptoms.
Typical motor symptoms of Parkinson ‘ s disease include static tremors, muscle rigidity, slow movement and positional balance disorder. The static tremors often manifest themselves in the uncontrollable shaking of the hand, which occurs in a quiet state, increases in emotion or stress and disappears after sleep. The rigidity of the muscle makes the body rigid and restricted, such as reduced facial expressions, a “face mask” and as difficult to stretch as the “frozen” body. The slowness of the exercise is reflected in the slowness of the movement, which has become difficult in day-to-day activities such as dressing, washing, writing, etc., and when walking at a smaller, slower pace, with a “frightful pace”. The positional balance disorder can make patients vulnerable to loss of balance and fall, seriously affecting mobility and self-reliance.
In addition to motor symptoms, Parkinson’s disease is accompanied by non-motor symptoms. The loss of smell is a common early expression, and patients may be less sensitive to the scent. Sleep disorders are also common, such as insomnia, multiple dreams, awakening or rapid eye contact disorders. In addition, there may be symptoms of constipation, depression, anxiety, cognitive disorders, which often exist at an early stage of the disease but are easily neglected, making early diagnosis difficult.
The causes of Parkinson’s disease have not yet been fully identified, but research has found to be related to a variety of factors, including genetic, environmental and nervous system ageing. Family genetic factors play a role in some patients, while long-term exposure to certain environmental toxins, such as pesticides and heavy metals, can increase the risk of disease. As the age increases, the brain dopamine is able to degrade neurons, and it is also responsible for Parkinson ‘ s disease.
At present, Parkinson ‘ s disease cannot be fully cured, but through a combination of reasonable medication, rehabilitation training, surgical treatment and psychological support, it is possible to effectively control symptoms, improve the quality of life of patients and extend the duration of life. Drug treatment is the preferred option, with common drugs such as left-rotated dopamine formulations, supplementing brain dopamine deficiencies and significantly improving motor symptoms, but as the disease progresses, the efficacy of treatment may diminish and there are motor complications. Drugs such as dopamine receptor agonists, monomamine oxidation B inhibitors, and chlorophenol-oxy-methyl transfer enzyme inhibitors can also be used at different stages of treatment or in combination with Circumpla. Rehabilitation training is essential to improve the physical functioning and balance of patients, including physical therapy, occupational therapy, speech therapy and ingestion training, to help them maintain their physical functioning and improve their self-reliance. In cases where medications are ineffective or there are serious motor complications, surgical treatments such as deep brain electro-stimulation (DBS) can be an option for irritating specific brain regions by implanting electrodes, regulating neuroactivity and improving symptoms. Psychological support should also not be overlooked, as Parkinson ‘ s patients often suffer from emotional problems such as depression and anxiety caused by illness, and family and medical personnel should give care and understanding and, if necessary, provide psychological counselling or medication.
