In the context of gastrointestinal diseases, Crohn ‘ s disease is a more complex and difficult disease, like a “chronic puzzle” in the intestinal tract, plaguing a large number of patients and provoking widespread attention in the medical field.
The causes of Crohn ‘ s disease have not yet been fully identified and are now widely believed to be caused by the interplay of factors. Genetic factors play an important role in this, and research shows that populations with specific genetic mutations are at a relatively high risk of Cron disease. At the same time, environmental factors, such as unbalanced diets, lifestyles and intestinal microbial communities, can also play a role in the development of the disease. In addition, anomalous activation of the immune system is a key link, with the body ‘ s immune system erroneously attacking intestinal tissue, leading to a chronic intestinal inflammation response, leading to a series of symptoms and pathologies.
In terms of intestinal pathology, Cron can be excruciated from the whole digestive tract from the mouth to the anus, but the most commonly irritated parts are the end-end intestines and colons. The fact that the pathologies appear in symmetrical distribution, i.e. that the normal part of the intestinal tract is in staggered with that of the pathological part, is an important feature of Cronn disease. The ulcer of intestinal mucous membranes, which may be of light ulcer form at an early stage, can deepen, grow and merge with each other as the condition progresss, creating ulcer and crack ulcer, which can even penetrate the intestinal wall in serious cases, causing complications such as intestinal piercing and fistula formation. The intestinal wall is also thickened and hardened by inflammation, with a narrow bowel cavity that affects the normal intestinal creeping and digestive absorption function.
The diversity and diversity of the symptoms of Crohn ‘ s disease also makes it more difficult to diagnose. Common symptoms include abdominal pain, which is mostly found in the lower right abdomen or umbilical weeks, and the nature of the pain, which can be insinuated, hurried or blunt, with irregular onset times, sometimes aggravated after eating. Diarrhoea is also a more prominent symptom, with an increase in the number of defecations, which can be defecated with paste or rare water, and can be accompanied by slime and sept in serious cases. Due to intestinal ingestion, patients tend to suffer from body body-weight loss, malnutrition, anaemia, and may be associated with whole-body symptoms such as fever, inactivity and joint pain, as chronic intestinal inflammation triggers a systematic body immune response.
Doctors need comprehensive information on how to diagnose Crohn. A detailed examination of the patient ‘ s medical history, including the time, frequency, severity, family history and past treatment, is an important basis for diagnosis. Laboratory examinations detect indicators such as blood routines, blood sank, C reaction proteins, etc., to assess the extent of inflammation; septic sub-blood tests help to understand whether haemorrhage exists in the intestinal tract. Endoscopy is one of the key tools for diagnosis, and colonoscopy can directly observe ulcer, inflammation, narrowness, etc., and can perform a live examination and obtain tissue samples for a pathological examination to clearly diagnose and determine the severity of the disease. The examination of small intestines, capsules, etc. helps to observe the pathologies of the small intestines, which are one of the good hairs of Crohn ‘ s disease, but which are difficult to reach. In addition, video screenings such as intestinal transective imaging and CT intestinal imaging can provide an important reference for the development of diagnostic and treatment programmes by showing the whole intestinal form, pathologies and the presence of complications, such as fistula and sepsis.
The treatment of Cronn ‘ s disease is a long-term and complex process aimed at controlling inflammation, mitigating symptoms, maintaining mitigation, preventing complications and, to the extent possible, improving the quality of life of patients. Treatment programmes are developed on an individual basis, depending on the seriousness of the patient ‘ s condition, his or her pathology and individual differences. Drug treatment is the primary treatment, including amino-hydrazine, sugar-coline hormones, immunosuppressants, biological agents, etc., which can contain intestinal inflammation and reduce symptoms, but each drug has its own specific adaptive and side effects and needs to be used under close medical supervision. In some cases of serious complications, such as narrow intestinal tracts, perforation, fistula, etc., surgical treatment may be required, but it is not possible to cure Crohn ‘ s disease and has a high rate of post-operative relapse, thus requiring continued drug treatment after the operation to sustain the relief.
Cronn’s disease.
