In the invisible microworld, bacteria are everywhere. They inhabit vast lands, rivers and lakes, the air that people breathe, and even the human body and beyond. Most bacteria coexist peacefully with human beings, and some also play a vital role in human health, such as helping to digest food, synthetic vitamins, etc. However, there are also bacteria that are the cause of disease, e.g., yellow grapes that cause skin infections and pneumocococcals that cause pneumonia, which pose a serious threat to human health.
In the face of the threat of bacteria, anti-bacterial drugs have emerged as a powerful weapon against bacterial infection. From the discovery of penicillin at the beginning of the twentieth century, a new era of antibacterial drugs began, to the widespread clinical application of a wide variety of antibiotics, synthetic antibacterial drugs and so on, countless lives were saved by the use of antibacterial drugs. In surgical operations, antibacterial drugs can be effective in preventing post-operative infections, resulting in a significant increase in the success rate; for patients with infectious diseases, the timely and accurate use of antibacterial drugs can quickly control the condition, alleviate pain and reduce the duration of the disease.
However, with the widespread use of antibacterial drugs, bacteria are also evolving, creating resistance. The emergence of drug-resistant bacteria reduces or even nullifies the efficacy of otherwise effective antibacterial drugs. Today, the infection of drug-resistant bacteria, such as methooxin-resistant fungus (MRSA) and multi-drug-resistant nodules, has become a serious challenge for global public health. In some hospitals, medical costs have increased significantly as a result of the increase in the number of drug-resistant infections, the increased difficulty of treatment and the length of hospitalization. This not only places a heavy financial burden and health risks on the individual patient, but also places a great strain on the health system as a whole.
Rational use of antibacterial drugs is key to the mitigation of bacterial resistance. When prescribing antibacterial drugs, doctors should select the appropriate antibacterial drug variety, dosage, route of delivery and course of treatment based on a combination of the patient ‘ s condition, the type of fungi, and the results of the drug-sensitive tests. Patients are also required to strictly comply with medical orders and do not reduce their own volume, stop or change them. For example, antibacterial drugs should not be used blindly for most viral diseases, such as common influenza, and it is important that treatment of bacterial infectious diseases be carried out in a manner that ensures the complete eradication of pathogens and the prevention of the creation of resistant bacteria.
In addition to the rational use of drugs, the development of new antibacterial drugs is an important way of dealing with bacterial resistance. Scientists are constantly exploring new drug target points, screening anti-bacterial-active substances from natural products, and developing new anti-bacterial drugs through technological means such as chemical synthesis and genetic engineering. New types of antibacterium, cactus therapy, etc. are also emerging as hot spots for research, giving new hope for the problem of bacterial resistance.
In addition, researchers are actively exploring the development of new anti-bacterial drugs. They conduct in-depth research on the biological properties of bacteria, metabolic mechanisms and drug target points, try to find inspiration from natural products, microbiological metabolites or innovative chemical synthesis methods, and develop antibacterial drugs with completely new mechanisms to break the existing resistance. At the same time, new and emerging antibacterial technologies, such as antibacterium, cactus therapy and nanobacterial materials, have emerged, providing new ideas and directions for combating bacterial infections.
During the long journey of bacteria with human beings, antibacterial drugs were the light of hope to disperse the disease. We need to take a scientific and cautious approach to antibacterial drugs, use them rationally and actively develop them so that the antibacterial light continues to shine and protect human health on the side of bacteria.
