Acute pancreas is a common abdominal condition, with complex changes. Multiple factors need to be taken into account in the choice of antibacterial drugs.
First, it is important to understand the potential for infectious pathogens of acute pancreas. Pancreas infections are mainly caused by intestinal bacterial transvestites, with common gland cactus, e.g., creber, intestinal bacterium, etc., and anaerobic bacteria, e.g., fragile bacterium. Thus, antibacterials of antibacterial drugs need to be able to cover these major pathogens.
I. Types and characteristics of commonly used antibacterial drugs
1. quinone
– In the case of the left oxen salsa, for example, it is the third generation of quinone. It has a broad antibacterial spectrum and has good antibacterial activity for most gerranes, including intestinal bacterium, such as coliform. It inhibits the activity of bacterial DNA rotor enzymes (bacterium expulsion isomerase II), hinders the reproduction of bacterial DNA and thus acts as a microbicide.
Circumplasia is also a common drug of quinone, with a certain concentration in pancreas tissue. Its antibacterial activity against the grenacella has some effect on the prevention and treatment of bacterial infections that may occur early in acute pancreas. However, the long-term use of quinone-type drugs may result in bacterial resistance and may have some adverse effects, such as gastrointestinal reaction, central nervous system response, etc.
Carbon cyanide
– Amphetamine Penan is the typical representative of this type of drug. It has an extremely broad antibacterial spectrum, with strong antibacterial activity for the Gerang-positive, geran-negative and anaerobic bacteria. It can kill bacteria by inhibiting the synthesis of bacterial cell walls, and is a very effective drug for severe acute insulin co-infection, especially in cases where multiple drug-resistant infections are possible.
– The antibacterial spectroscopy in the United States of America is similar to that in the case of amphetamine, but in some respects, for example, the safety of the central nervous system may be better. In cases of acute pancreas disease, carbon-cyanide drugs can control the infection quickly and effectively when there are suspected of serious infections such as sepsis and pancreas sepsis. However, such drugs may have adverse effects, such as allergies, gastrointestinal reactions, etc., and are relatively expensive.
3. Nitromazole
– Tetranitrazine is the type of nitromethylazine commonly used for the treatment of acute pancreas. It has a special effect on anaerobic bacteria, which can cause bacterial cell DNA spirals to rupture or prevent their synthesis and cause bacterial death. In acute pancreas, it is used mainly for co-use with other anti-glucosis drugs to prevent and treat intraperitoneal infections, which are often caused by a combination of aerobic and anaerobic bacteria.
– Nitrazine is also a nitromazole-type drug with similar antibacterial activity and amytazine, but may differ in the metabolic dynamics of the drug, such as a longer period of time.
Considerations for the selection of antibacterial drugs
1. Extent of the situation
For light acute pancreas, the use of antibacterial drugs is generally considered when there are signs of infection, with the option of a relatively narrow spectrum, such as quinone. For acute acute pancreasitis, because of its susceptibility to co-infection, and because it is often more severe when it occurs, it may require the use of high-impact, wide-scale antibacterial drugs, such as carbon cyanide, at the outset.
2. Possible species of pathogens
– If the pathogen type is determined, for example, by means of culture, the most sensitive antibacterial drugs can be selected on the basis of the results of the drug-sensitive tests. In many cases, however, initial treatment is empirical and needs to be selected on the basis of common pathogens. For example, when anaerobic infections are suspected, there is a need for the joint use of nitromazole-type drugs, such as methagen.
3. Individual differences between patients
– The age of the patient, gender, underlying diseases, etc. affect the choice of antibacterial drugs. For example, older patients may suffer from a reduction in liver and kidney function and need to adjust the dose of the drug; pregnant women need to consider the effects of the drug on the foetus and avoid the use of potentially teratogenic drugs.
In sum, the choice of antibacterials for acute pancreas is a complex process that requires a combination of factors such as the condition, the pathogen and the individual circumstances of the patient, and should be used rationally, under the strict guidance of a doctor, in order to achieve the best possible treatment, while avoiding the abuse and adverse reactions of antibacterials.
