In the long history of human struggle against disease, the emergence of anti-bacterial drugs is undoubtedly a milestone, providing a powerful means of treating various bacterial infectious diseases. Over time, however, the abuse of antibacterial drugs has become more serious, with the shadow of modern medicine, and the resulting problem of bacterial resistance has become one of the major challenges to global public health.
Anti-bacterial drugs strike bacteria with precision through a variety of unique mechanisms. Beta-neamide antibiotics, represented by penicillin, can ably inhibit the synthesis of bacterial cystal walls, preventing bacteria from surviving in normal biological conditions and eventually leading to death due to cell dyslexia, while fluorophenone antibacterials focus their active target on bacteria’ DNA Rotation enzymes, effectively preventing bacteria’ reproduction and proliferation by interfering with bacteria’ DNA reproduction processes. It is with these remarkable antibacterial properties that antibacterial drugs have succeeded in saving countless patients from severe bacterial infections over the past few years. For example, in the face of diseases such as red fever and bacterial pneumonia, which have ravaged the past, the use of anti-bacterial drugs has significantly reduced the mortality rate of patients, significantly improved their prognosis and served as a battle for human health.
Tragically, however, the abuse of anti-bacterial drugs is like an invisible disaster, spreading indiscriminately in the medical field and in society at large. In some primary health-care institutions or in the scenes of patients using their own medicines, there are often worrying signs of drug use. Many people take antibacterial drugs without conceiting when they have symptoms such as fever and cough, ignoring the fact that they are highly likely to be caused by the infection, which has little power over the virus. Such blind use of drugs not only fails to achieve the desired results in treating the disease, but can have many negative effects on the body as a result of the improper use of drugs. At the same time, some medical personnel have not strictly complied with the reasonable use of anti-bacterial drugs in clinical practice. The overuse of broad-spectral antibacterial drugs, or serious deviations in the control of the dose and treatment process, is associated with the temptation of profit or inaccurate diagnosis of the condition. This irrational use not only results in a great waste of medical resources, but also creates excellent conditions for bacterial resistance.
The hazards of increased bacterial resistance are extremely serious and far-reaching. Once bacteria are resistant to some anti-bacterial drug, the otherwise conventionally effective treatment will lose its effectiveness at short notice, making effective control of the patient’s condition difficult, the treatment cycle will be significantly extended and the cost of treatment will increase dramatically. Even worse, drug-resistant bacteria can spread rapidly among the population, causing a large-scale epidemic of infection and posing a great threat to the public health of society. For example, the emergence in recent years of a carbon cormoxins resistant intestinal bacteria (CRE), which are highly resistant to almost all available antibacterial drugs, has caused severe headaches in the global medical community in the event of infection and mortality. The studies predict that, if the growth of bacterial resistance is not curbed in a timely and effective manner, in the near future we will most likely return to the dark age of drug-free exposure to bacteria.
In order to effectively reverse this negative situation, there is an urgent need to promote the rational use of anti-bacterial drugs throughout society. For the general population, efforts should be made to raise its own medical literacy and health awareness and to firmly reject the undesired habit of buying and using antibacterial drugs at will. If the body is not present in due course, it should visit the regular health-care facility in a timely manner, following the doctor ‘ s professional diagnosis and treatment recommendations, and must not use the medication blindly. The health-care system has more important responsibilities and responsibilities. The professional training and education of medical personnel should be further strengthened, and their level of awareness and operational capacity to counter the rational use of bacterial drugs should be continuously improved. In the course of clinical treatment, the guidelines and norms for the use of antibacterial drugs are strictly followed, the appropriate antibacterial drugs are selected with precision, based on the patient ‘ s specific condition, the type of fungi and the results of the drug-sensitive tests, and a scientifically sound dose and course of treatment is developed. At the same time, there is a need to establish a sound monitoring and management mechanism for the use of anti-bacterial drugs, to strengthen the overall monitoring of the use process and to detect and correct in a timely manner unjustified drug use. In addition, government departments and relevant scientific institutions should increase their investment in anti-bacterial drug research and development, actively encourage innovation and work towards the development of more new, efficient and low-toxic anti-bacterial drugs, with more choice and strong support for clinical treatment.
Antibacterial drugs are a precious asset in the medical arsenal of humanity, and we must use this powerful weapon rationally with a high sense of responsibility and purpose to fight together the serious challenge of the bacterium-resistant crisis. Only in this way can we ensure that anti-bacterial drugs will continue to protect the health of humankind in the future, so that it will always prevail in the long struggle against bacteria and write a new chapter of health and hope.
