Antibacterial drugs are a powerful weapon in our hands during the journey against disease. However, when antibacterial drugs are taken in conjunction with other drugs, it is like entering a complex “circle of friends” in which interactions can affect the efficacy of the drug and even produce adverse effects. Understanding these interactions is essential for our rational use of drugs and for our health.
The variety of antibacterial drugs and their different mechanisms of operation also determine that they produce different “chemical reactions” when they are co-opted with other drugs. In the case of commonly used antibacterial drugs, such drugs can cause an uncomfortable “disulphine-like reaction” if they are consumed simultaneously with alcohol-containing drinks or drugs. This is because hemorrhoids inhibit the activity of the acetylene dehydrogenase in the liver, which prevents the successful conversion of acetylene from the alcohol metabolism process to acetic acid and thus accumulates in the body. Patients may have symptoms of facial redness, headache, dizziness, panic, agitation, breathing difficulties, nausea, vomiting and even life-threatening conditions. Therefore, during the use of a drug like a sepsis and for a period of time after its suspension (usually about 7 days), it is necessary to strictly refrain from drinking any food, beverage or drug containing alcohol, such as wine heart chocolate, fragrance and so forth.
Also, antibacterial drugs such as quinone, such as left-oxen fluoride salsa, if taken at the same time as those containing metallic ions such as magnesium, aluminium, calcium (e.g., anti-acid aluminum hydroxide, calcium preparations, etc.), metal ions form sequesters with quinone-type drugs and reduce their absorption in the gastrointestinal tract, thus reducing their antibacterial effects. Both types of drugs should therefore be administered at intervals of 2-4 hours to ensure that quinone-type drugs are fully functional.
In addition to the common situation described above, there are a number of anti-bacterial drugs whose interaction with other drugs is of concern. For example, when co-existed with certain cardiovascular drugs (e.g., erythrocycin, carcinocin), the Great Ring Iester antibacterial drugs (e.g., e.g., geocoxin) can influence the metabolism of geocin, increase its blood concentration in the body and increase the risk of hypersyncin poisoning, which can lead to serious consequences such as cardiac disorders. Therefore, when patients are taking both types of medication, doctors need to closely monitor the blood concentration at geoincin and adjust the dosage to the situation.
For the two special groups of children and the elderly, greater care should be taken in the use of anti-bacterial and other drugs. The fact that the organs of the child ‘ s body are not fully developed and that drug metabolic capacity is relatively weak increases the complexity and risk of drug interactions, as well as the likelihood of multiple underlying diseases among older persons and the more common use of multiple drugs. For example, when children use anti-bacterial drugs to treat infection, if they take drugs containing analgesic analgesics due to co-infections with flu, they may increase the likelihood of adverse reactions, such as liver and kidney impairment, gastrointestinal discomfort, etc., as a result of drug overloading. The use of anti-bacterial drugs by older persons, together with such drugs as blood resin and blood pressure, may interfere with each other ‘ s metabolic processes by affecting the activity of the liver metabolic enzyme, leading to increased or diminished efficacy and even new health problems.
How, then, should we avoid the poor interaction of antibacterial drugs with other drugs? First, doctors must be informed in detail of all drugs they are taking, including non-prescribed drugs, health-care products, etc., in order to provide them with a comprehensive picture of their use, in order to determine accurately whether there are potential drug interactions and to adjust treatment programmes. Secondly, the medication is strictly prescribed by the doctor, without any increase in the dosage of the drug or any random combination of it. If non-prescribed drugs need to be purchased on their own, the drug instructions should be carefully read, taking into account the content of the drug and the warning of interaction.
The interaction of antibacterial drugs with other drugs during the same time is a complex and critical issue. We need to increase our sense of self-protection, knowledge, and work closely with doctors to ensure that every drug is safe and effective and that drugs better serve our health, rather than because interactions cause unnecessary troubles and risks. Only then will we be able to move steadily on the path to the fight against disease and to safeguard our health and that of our families.
