Antibiotics of quinone are one of the most widely used clinical antibacterials with a wide spectrum of antibacterials, strong resistance, high tissue concentrations and good oral absorption. However, in the use of such drugs, a number of important issues need to be addressed to ensure their safety and efficacy. The following is a detailed description of the attention given to the use of antibiotics of quinone:
I. Applicability of population groups and taboos
(b) Prohibited use of children: Qenone-type drugs are not suitable for use in children, as they may cause cartilage with heavy joints, causing joint pains and joint oedema. Children ‘ s cartilages and joints are not fully developed and their use may cause irreversible harm.
Pregnant and lactating women who are careful to use or disable: Drugs such as quinone may affect the normal development of the foetus and even lead to serious consequences such as abortion. At the same time, the drug component may also pass on to the baby through milk, affecting the healthy growth of the baby. Consequently, pregnant and lactating women should refrain from using them or use them with caution under the guidance of a doctor.
Disappearment of allergies: Patients who are allergic to quinone-type drugs should be prohibited, otherwise they may have an allergic reaction such as rash, abdominal pain, respiratory difficulties, and even life-threatening.
Psychiatry history is banned: quinone-type drugs have a certain ecstasy effect and may aggravate the symptoms of the mentally ill. Those with a history of mental illness should therefore refrain from using such drugs.
Careful use of kidney abnormalities: quinone-type drugs may increase the kidney burden, leading to symptoms such as blood urine, tube urine, etc. In the case of patients with abnormal kidney function, appropriate reductions should be made under the direction of a doctor, depending on the reduction in kidney function.
Other special groups: epilepsy patients, persons with serious muscular incapacities and persons with diabetes should also be careful with quinone-type drugs, which can induce epilepsy, increase acute muscular incapacitation or cause blood sugar abnormalities.
Drug interaction and taboos
Avoid sharing with other drugs:
Qenone-type drugs are not suitable for co-use with tea-alkali drugs and non-silent anti-inflammation drugs to avoid central neurotoxic effects.
Co-opting with anti-acid, metal ion-containing drugs (e.g. aluminium, magnesium acids) reduces the absorption effect of drugs and reduces the efficacy of treatment.
It is not appropriate to use proposulfon, alkaline, etc. at the same time so as not to affect the excretion and metabolism of drugs.
The risk of heart disorder is reduced by avoiding co-opt with medications that extend the Q-T period of the heart (e.g. West Sabri, erythrin, tricyclic antidepressants, etc.).
Note the interval between drugs: If other drugs are to be used jointly, use of quinone-type drugs should be avoided as much as possible, and appropriate time intervals should be determined in accordance with medical guidance. For example, blood concentrations of immunosuppressants should be monitored when used in conjunction with immunosuppressants, such as epoxy, to avoid increased immunosuppressive effects and renal toxicity.
III. Care during use
Post-dinning: In order to reduce the irritation of gastrointestinal tracts by quinone-type drugs, after-dinning is generally recommended. This helps to alleviate the symptoms of nausea and vomiting.
Observation of adverse effects: During the use of the drug, the patient should closely observe the occurrence of adverse effects, such as vomiting, headaches, skin itching, red spots, etc. In case of discomfort, the medication should be stopped and treated.
Avoiding long-term suntan: oxidation of oxidizing activated oxygen in ultraviolet light can cause skin inflammation. The patient should therefore avoid long periods of exposure to sunlight, particularly in areas that are susceptible to sunlight, such as the arm, leg, face and neck, during the use of the drug.
Regular monitoring of liver and kidney function: The long-term use of quinone-type drugs may have some effect on liver and kidney function. Therefore, special groups such as the elderly and children should use them regularly for routine blood tests and for liver and kidney function monitoring to ensure the safety of the medication.
Note the velocity and time of drip: The velocity and time of drip should be controlled for quinone-like drugs (e.g., cyclopropa and chlorofluorosaltron) requiring intravenous drips. In general, dripping should take more than 60 minutes and slow dripping can minimize the discomfort of the patient.
Other matters of concern
Medicinal compliance: In the use of quinone-type antibiotics, the patient should comply strictly with the doctor ‘ s instructions and take the medication on time and in accordance with his/her rate. Do not increase or alter the use of the drug to affect the efficacy of treatment or increase the risk of adverse effects.
Keep the diet low: During the time of the drug use, the patient should keep the diet low and avoid eating too greasy, spicy or irritating food. This helps to reduce the gastrointestinal burden and promotes the absorption and use of drugs.
(b) Heating measures: In order to avoid worsening the condition due to cooling or new infections, the patient should be careful to provide heating measures during the time of use. Especially in low-temperature seasons, clothing is added in time to prevent diseases such as flu.
Based on the above, there are a number of aspects that need to be addressed in the use of quinone-type antibiotics to ensure the safety and efficacy of the drug. Patients should strictly follow doctor ‘ s guidance for the use of drugs and regularly monitor indicators such as liver and kidney function to assess the efficacy and safety of the drugs. At the same time, care must be taken to maintain good living and eating habits to promote physical recovery and health.
