Several such patients are admitted to emergency and critical care departments every year, and they share some common characteristics.
Basic information: gender and age are not limited, and they are healthy in the past. Suspected history of eating unclean food (such as leftovers).
Morbidity features: acute morbidity, nausea, vomiting, abdominal pain or abdominal discomfort, with or without diarrhea; severe confusion, decreased blood pressure (need to use pressor drugs), decreased urine volume, expiratory dyspnoea (severe need to use ventilator-assisted correction of hypoxia). What’s more, when the emergency personnel arrived at the scene, the patient had respiratory and cardiac arrest.
Laboratory examination showed that the number of white blood cells increased or decreased sharply, other infection indicators such as C-reactive protein, procalcitonin, interleukin-6 increased significantly, blood lactic acid increased, platelets decreased in severe cases, serum creatinine increased, bilirubin increased, coagulation function was abnormal, blood gas analysis showed that oxygen partial pressure was significantly lower than normal, metabolic acidosis.
A previously healthy person, suspected of eating unclean food, not only leads to simple gastroenteritis, vomiting and diarrhea, but also multiple organ function damage in a short period of time, even respiratory and circulatory failure, respiratory and cardiac arrest.
A well-trained emergency or intensive care physician, seeing such a patient, combined with these clinical and laboratory data, can make an accurate and decisive diagnosis: sepsis! Multiple organ dysfunction syndrome!
Where does the poison come from?
Through the mouth!
The culprits consider eating unclean food.
In terms of treatment, every minute counts to save lives: 1. Fluid infusion, pressure boosting, application of powerful broad-spectrum antibiotics to correct shock; 2. Oxygen therapy, if necessary, ventilator to correct hypoxia; 3. Organ support, including heart, liver, kidney, coagulation system, etc., if necessary, transfusion of blood products and blood purification treatment; 4. At the same time, complete etiological examination such as blood culture, stool culture, etc.; 5. In some patients with respiratory and circulatory failure or even respiratory and cardiac arrest in a short period of time, extracorporeal cardiopulmonary resuscitation (ECPR, that is, cardiopulmonary resuscitation assisted by ECMO), active multi-organ support after cardiac recovery, and active cerebral resuscitation.
Current medical conditions, as long as timely and standardized treatment, most patients can recover without organ dysfunction; a small number of patients after active treatment, but eventually left some organ dysfunction, such as chronic renal insufficiency, need regular dialysis; Some ECPR patients, after rescue, their vital signs were stable, the degree of cerebral hypoxia and ischemia was too serious, and it was difficult to recover consciousness; of course, some patients with breathing and heartbeat eventually died.
They may only eat a few leftovers and leftovers, leading to sepsis, multiple organ failure, and eventually death.
What kind of poison was exposed to? Bacteria or fungi were detected in some patients, and some patients could not detect any specific bacteria at all. It is certain that some toxins enter the body and induce inflammatory storms, leading to multiple organ damage.
The most regrettable thing is that many of them are young people in their prime.
So, how can we prevent such terrible things from happening in our daily life?
1. Leftovers should be put into the refrigerator in time, covered with plastic wrap and refrigerated, and fully heated before eating, especially meat food; restaurants with standard environmental hygiene should be chosen for dining out; 2. Moldy food must be discarded! It was found that the food had a musty smell accompanied by yellow, blue spots or fine hairs, which were the characteristics of food mildew. Moldy food not only reduces its nutritional value, but also often contains mycotoxins, which are not afraid of high temperature and can not be destroyed by common food processing methods such as frying, frying, boiling, steaming and frying. 3. Household measures to prevent food mildew: grain should be placed in a cool, ventilated and dry place, not on the ground against the wall, so as to avoid dampness and mildew. In case of dampness, it should be aired in time. Mild moldy rice should be washed several times when cooking, and serious ones should be discarded. Moldy peanuts should be picked out and thrown away one by one; the moisture content of cakes is generally 15%, do not store them for a long time, even if they are stored in a refrigerator, they will become moldy for a long time. Bread should not be stored for more than three days and should be bought with food. The storage time of cream cake is 3 days in winter, 2 days in spring and autumn, and 1 day in summer. The date of production should be seen clearly when purchasing. The water content of biscuits, milk powder and dried fruits is generally below 5%, and it is easy to absorb moisture and mildew. It should be placed in a covered iron box. It is best to put desiccant in the box to maintain the flavor of food and prevent mildew. Remember: Disease comes from the mouth! Sepsis
