Breast cancer bone transfer means that breast cancer cells spread to the bones, including through blood circulation, and grow into transfer stoves within the bones. First, clinically manifested pain is the most common symptom, most of which can be aggravated by persistent pain in fixed areas. The degree of pain varies from one person to another to a lesser degree of pain, which occurs only in cases of activity or pressure, to severe pain, which affects sleep and daily life. The pain is usually related to the location of the shifting stove, and common areas include the spine, ribs, pelvis, femur, etc. For example, spinal transfers can cause back pain, sometimes from radiation to lower limbs; rib transfers can cause chest pain, etc. Modular fractures can occur when tumours break the bones, reducing the strength of the bone tissue. Reasonable pathological fractures usually occur with a slight or no visible external force, and may result in fractures such as coughing, bending and flipping. Common fractures include spines, femur necks, gillbones, etc. After a fracture, the patient suffers from symptoms of increased local pain, swelling, deformity and restricted mobility. The transfer of breast cancer from high calcium can destroy bone tissue and release large amounts of calcium into blood, leading to high calcium haemorrhage. Symptoms of high calcium haemorrhage include nausea, vomiting, an appetite, constipation, inactivity, sleeping, urination, thirst, etc. Severe calcium haemorrhagic conditions can cause life-threatening complications such as cardiac disorders and kidney failure. Spinal oppression can give rise to symptoms of spinal oppression when the spinal transfer stove increases and the spinal cord is repressed. Patients can suffer from symptoms of lower limb numbness, weakness, pain, abnormal feeling and incontinence. In the absence of timely treatment, spinal oppression can lead to permanent neurological impairment. Diagnosis video-check X-rays: One of the most common methods of detection, which can be found in parts, sizes, forms, etc. of bone transfer stoves. However, the X-ray is less sensitive to early bone transfer and can only be detected if the bone transfer stove destroys a certain amount of bone tissue. Bone scan: Also known as body oscillation, it is a more sensitive method of examination, which detects the pathology of the body. Bones scans can detect anomalies before symptoms such as pain in bone transfer stoves are detected, which is important for early detection of bone transfer. However, the specific nature of bone scans is low, the nature of the pathogen cannot be determined and will need to be diagnosed in conjunction with other screening methods. CT Inspection: More detailed information on bone structure can be provided, which is important in determining the extent of bone transfer stoves, the extent of damage and the relationship with the surrounding tissue. CT can also detect complications such as swollen tissues and rational fractures. MRI Screening: The high sensitivity and specificity of bone transfer in the vertebrae can clearly show the pressure of the spinal cord, nerve root, etc. MRI inspections are very useful for early detection of bone transfer and assessment of the extent of spinal pressure. Laboratory examination of sero-alkaline phosphate enzymes (ALP): increased skeletal cell activity during bone transfer can lead to sero-ALP rise. However, the ALP rise can also be seen in other diseases, such as liver diseases, epidemiology, etc., so that they are not highly specific. Serum calcium: As previously mentioned, bone transfer can cause high calcium haematosis and serocal calcium rise. But serocal calcium does not rule out bone transfer. Oncological markers: Oncological markers associated with breast cancer, such as the CEA, CA15-3 may be elevated at the time of bone transfer, but the rise of these markers may also be related to the transfer of other parts or the re-emergence of breast cancer and cannot be used as a separate basis for the diagnosis of bone transfer. Pathological examinations of cases that are difficult to identify can be carried out in tissues that can obtain bone transfer stoves by means of a stabbing biopsy or surgical removal in order to clearly diagnose them. Pathological examinations are the gold standard for the diagnosis of bone transfer, but because of their originality they are not usually the preferred method of examination. iii. Treatment for bone transfer for the treatment of dithiolates: bithiolates can inhibit the activity of broken bone cells and reduce bone damage, thereby reducing bone pain and the risk of rational disease fractures. Commonly used bisalphate drugs include acrylic acid and Ibanic acid. Duplexate-type drugs usually require long-term use, once every 3 – 4 weeks. Radionuclide treatment: Some radionuclides, such as thorium-89 and thorium-153, can be assembled in the bone transfer stoves, killing tumor cells by firing beta rays, thus reducing bone pain. Radionuclide treatment is generally applied to patients with a full-body multiple bone transfer and is not effective for patients with one or a few bone transfer stoves. Surgical treatment: Surgery may be required for patients suffering from rational fractures or spinal cord oppression. The purpose of the operation was to stabilize fractures, remove spinal pressure and restore neurological function. The procedure includes internal fracturing, vertebraeformation, vertebrae decompression, etc. Chemotherapy for the whole-system treatment of breast cancer: If the breast cancer patient has a bone transfer and the tumor is sensitive to chemotherapy, chemotherapy can be considered. chemotherapy can control the progress of the disease by killing the entire body of tumour cells, including those in bone transfer stoves. The choice of a chemotherapy programme should be determined on the basis of the patient ‘ s specific circumstances and the pathological type of the tumor, molecular stratification, etc. Endocrine treatment: Endocrinological treatment is available for hormonal positive breast cancer patients. Endocrine treatment can inhibit the growth of tumour cells and slow the progress of the disease. The most common endocrinological treatments include his mosaics, curvatures, anacondas, etc. Target treatment: Target treatment is available for HeR2-positive breast cancer patients. Target-oriented treatments can be specific to HeR2 receptors on the surface of tumour cells and inhibit the growth of tumour cells. Common target-oriented treatments include tuto-chorus resistance and Patto-jumper resistance. Pain management medication: Pain caused by bone transfer can be treated with painkillers. The choice of analgesics should be determined by the degree of pain, and mild pain can be used with non-temperature anti-inflammatory drugs such as Brophine, Acetylaminophenol, etc.; moderate pain can be used with weak opioids such as codeine, tramadol, etc.; severe pain can be used with strong opioids such as morphine, fentanyl, etc. Radiotherapy: Radiotherapy can alleviate bone pain, especially for patients with visible local pain. Radiotherapy can reduce pain by killing tumor cells and reducing tumour irritation to bone tissues. Interventions: Interventions may be considered for patients suffering from severe pain and drug treatments. Interventions include neurotic retardation, irradiation, freezing and ablution, which can directly affect the nerve of the pain, disrupt the transmission of pain signals and thus relieve pain.
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