Breast Cancer Classification and its Clinical Importance
Breast cancer, the number one killer of women ‘ s health, can be divided into different types according to different classification criteria. Understanding these classifications and their clinical significance is essential for early diagnosis and treatment. First, according to the type of tissue, breast cancer is divided into two main categories: non-immersion and immersion. Non-immersed breast cancer, which includes intra-ductive and breast cancer, has not yet broken through the base membrane, is an early disease and has a high cure rate. Premised breast cancer includes immersion catheter cancer, immersional leaf cancer, etc. The breast cancer cells have broken through the base membrane, are immersed in the surrounding tissues, are more malignant and difficult to treat. Second, according to hormonal receptor, breast cancer can be classified as hormonal receptor positive (HR+) and hormonal receptor negative (HR-). There are estrogen receptors or gestation hormone receptors on the surface of hormonal receptor-positive breast cancers, which are sensitive to endocrine treatment and are relatively good. Hormonal receptor-negative breast cancer is insensitive to endocrine treatment and has a poor prognosis. In addition, according to herer2 genetic expression, breast cancer can be classified into two categories: Her2 positive and Her2 negative. HeR2 positive breast cancer is over-expressed on the surface of the HeR2-positive breast cancer, which is highly virulent and less prognostic, but is sensitive to the HeR2 treatment, such as the one-to-one drug. Her2 negative breast cancer is not sensitive to such treatment. Furthermore, according to molecular stratification, breast cancer can be classified into tube cavity A, tube cavity B, HeR2 concentration and base model. The pre-pregnosis for tube-type A breast cancer is better and is sensitive to endocrine treatment; the cavity-type B breast cancer is more malignant and sensitive to both chemotherapy and endocrine treatment; the HeR2 concentration breast cancer is more malignant and poor but sensitive to HeR2 treatment; and the base-type breast cancer is less sensitive to chemotherapy but lacks effective target-oriented treatment. Understanding the classification of breast cancer and its clinical significance is essential for early diagnosis and treatment. The different types of breast cancer, with different treatment methods and sensitivity to treatment, allow for individualized treatment programmes based on the classification of breast cancer to improve the effectiveness of treatment and improve patient prognosis. In short, the classification of breast cancer is a complex and important subject, which relates not only to the diagnosis and treatment of breast cancer, but also to the prognosis and quality of life of patients. Let’s start with the classification of breast cancer and get a better understanding of the disease and provide a scientific basis for the prevention and treatment of breast cancer.