Wang Xiaobin, a medical physician at the county hospital
I. The clinical use of sulfamic antibacterial drugs
(i) Treatment of urinary system infections
Sulfamic drugs are widely used in urinary system infections. For common diseases of the urinary system, such as bladderitis and kidneys, the antibacterial mechanism prevents the growth and reproduction of bacteria by inhibiting the synthesis of bacterial folic acid. The combination formulations of sulfamide and methoxazine have a good effect on the inhibition of common pathogens that cause urinary infections, such as coliform. It is an effective way to mitigate urinary tract irritation, such as urination, excrement and urinary pain, and to reduce the number of bacteria in urine and the recurrence of infections in the urology system.
(ii) Application of respiratory infections
Sulfamic drugs also have a role in respiratory infections. For some minor communities, there has been an acute outbreak of pneumonia, chronic bronchitis, etc., especially from sensitive bacteria such as pneumocococcus and haemophilus influenzae. Sulfamine-type drugs can reduce patients’ symptoms of coughing, coughing, fever, inhibiting the growth of respiratory pathogens and reducing inflammation.
(iii) Treatment of intestinal infections
Among intestinal infections, sulfamine-type drugs can be used to treat diseases such as bacterial dysentery and enteritis. In the case of intestinal bacteria such as Shiga, sulfamine-type drugs can perform anti-bacterial activity, relieve patients of abdominal pain, diarrhoea, acute stress, etc., and help restore intestinal function. Rational use of sulfamide-type drugs also plays a role in preventing the spread of intestinal infections.
(iv) Skin soft tissue infections
Infections of soft tissues, such as skin gills, gills and tan poisons, sulfamide-type drugs inhibit local pathogens. When the skin is bacterially infected by trauma or other causes, the use of sulfamine-type drugs can control the extent of the infection, reduce the inflammation of local red edema, promote the healing of the wound, prevent further spread of the infection to the surrounding tissue or cause full-body infections.
II. Attention to clinical applications of sulfamic antibacterial drugs
(i) Monitoring of adverse effects
Sulfan-type drugs form a crystallized urinary system, which is a relatively common and serious adverse effect. Symptoms such as blood urine, urinal pain and urinary confinement. In order to prevent crystal urine, the patient is required to drink a large amount of water during the time of the drug, ensuring a daily urination of 1,500 ml or more. At the same time, the solution of sulfamide-type drugs and their metabolites in urine can be increased through oral sodium naphthalm. 2. Allergies
Sulfamine-type drugs can cause allergies such as rashes, vascular neurological oedema and detached dermatitis. Serious allergies can endanger life. The patient ‘ s allergy history should be asked in detail before the drug is used, and it is prohibited for patients with sulfamides. In case of allergies, there should be an immediate stop and anti-allergy treatment. 3. Blood system response
There may be adverse reactions to the blood system in clinical applications, such as reduction in white cells, reduction in slabs and regenerative obstructive anaemia. In long-term or high-dose use of sulfamine-type drugs, regular blood tests are required in order to detect anomalies in a timely manner and adjust treatment programmes.
(ii) Drug interaction
Sulfamine-type drugs may interact with some of the drugs. For example, the combination of oral anticondensants may increase the risk of haemorrhage, as sulfamide-type drugs can be replaced with anticondensants combined with plasma proteins, increasing the level of freeing of anticondensants. Combining with sugar can increase the effect of sugar and lead to low blood sugar, which needs to be followed closely.
1. Sulfamide-type drugs for pregnant and lactating women may enter the foetus by placenta or be circulated by milk. It may have an impact on the chromosomal metabolism of the foetus or the infant, increasing the occurrence of nucleotide, so that pregnant and nursing women should be cautiously used or banned. 2. Children and the elderly The liver and kidney function of children is not fully developed, the liver and kidney function of older persons is reduced, the use of sulfamide-type drugs is subject to adverse effects, and the use of drugs requires close monitoring and dose adjustment.
