Composition of diabetic patients and etiology of diabetes mellitus

The composition of

diabetic patients can be analyzed from many aspects, including age, gender, regional distribution, complications and types of diabetes.

In terms of age and gender, men account for a higher proportion of diabetic patients, such as 66% of male patients and 34% of female patients, according to one study. In addition, the age range of diabetic patients is wide, ranging from young patients to elderly patients. In one study, for example, patients ranged in age from 24 to 98 years.

In terms of

regional distribution, there are differences in the distribution of diabetic patients in different regions. According to a survey, the number of diabetes patients in the eastern coastal areas is more than that in the central and western regions, and the number of patients in economically developed areas is also higher than that in economically backward areas.

In terms of

complications, diabetics often have other health problems. For example, some studies have pointed out that about half of diabetic patients have hypertension, one third of diabetic patients have diabetic fundus disease, and one quarter of diabetic patients have cardiovascular disease. In addition, patients with type 2 diabetes have a high proportion of obesity, accompanied by a variety of complications such as nephropathy, retinopathy and cardiovascular disease.

The type of

diabetes is also an important part of the patient population. Diabetes is mainly divided into type 1 diabetes, type 2 diabetes, special type diabetes and gestational diabetes. Among them, type 2 diabetes is the most common type, accounting for more than 90% of the total diabetic population.

The composition of

diabetic patients is diverse, including different age, gender, regional distribution, as well as a variety of complications and types of diabetes. These factors together affect the management and treatment strategies of diabetic patients.

The etiology of

diabetes is multifaceted, involving genetic factors, environmental factors, lifestyle and other aspects.

Genetic factors play an important role in the morbidity of diabetes. Studies have shown that there is an obvious tendency of family morbidity in diabetic patients, and about 25% to 50% of diabetic patients have family history of diabetes. Specifically, both type 1 diabetes and type 2 diabetes show genetic heterogeneity, that is, different gene variants may lead to different types of diabetes. Type 1 diabetes, for example, is associated with variations in HLA genes that affect the function of the immune system, leading to an autoimmune response that destroys islet beta cells. Type 2 diabetes, on the other hand, is associated with variations in multiple genes that affect insulin production, action, and glucose metabolism.

Environmental factors are also important inducements for morbidity of diabetes mellitus. Obesity, lack of exercise, unhealthy eating habits and mental stress are all important environmental factors leading to diabetes. Obesity plays a key role in type 2 diabetes in particular, because fat tissue releases inflammatory substances and hormones that interfere with insulin signaling, leading to insulin resistance. In addition, viral infection is also considered to be one of the main predisposing factors of type 1 diabetes, and some viral infections may activate autoimmune reactions, thereby destroying islet beta cells.

Lifestyle and behavioral factors also have a significant impact on the morbidity of diabetes. For example, lack of physical activity, high sugar diet and unhealthy lifestyle habits can increase the risk of diabetes. In addition, diabetes during pregnancy (gestational diabetes mellitus) also proves the importance of kidney qi deficiency and other factors in the morbidity of diabetes.

In conclusion, the etiology of diabetes is complex, involving many factors such as heredity, environment and lifestyle. These factors interact with each other and lead to the occurrence and development of diabetes.