Diabetic Neuropathy is one of the chronic complications common to diabetic patients, mainly due to long-term high blood sugar-induced damage to the surrounding nervous system. This pathology can affect sensory, motor and autonomous nervous functions, leading to a series of clinical symptoms and signs.
Diabetes neurological changes are of various types, including, inter alia, symmetric multineurological changes, autonomous neuropsychiatric changes, and mononeurological changes.
Of these, symmetrical multi-neurological pathologies are the most common types, usually expressed as loss of feeling, pain and vibration at the far end of the limbs, similar to the distribution of “socks” or “mittens”. Autonomous neurosis involves the autonomous nervous system of the internal organs, which can lead to problems such as hysteria, blood pressure fluctuations, constipation, gastrointestinal dysfunction and sexual dysfunction.
Diabetes neurological conditions are complex and high blood sugar is the main contributing factor, but its specific mechanisms include metabolic disorders, microcircle disorders and immune system anomalies. High blood sugar levels can damage neurofibre, lead to the loss of demigodium and nonmiladium fibres, and trigger Wallerian decomposition. In addition, the accumulation and inflammation response of the end-of-life product (AGE) of late-term sugar glucose radicalization plays an important role in the pathology process.
Diagnosis of neurological changes of diabetes relies on detailed medical history collection and medical examination, which assesses the neurofunctional function in combination with electrophysiological tests such as the FEMG and neurotransmission velocity measurements. In addition, techniques such as quantitative sensory testing (QST) and amplitude focus microscopes are also used for early detection and monitoring of the progress of neurotransformations.
In the area of treatment, there are no special effects drugs for the reversal of nervous damage due to diabetes. Controlling blood sugar levels is a key measure to prevent and mitigate progress and can be effectively controlled through dietary management, appropriate exercise and drug treatment. For symptoms management, commonly used drugs include antidepressants, anti-convulsive drugs and local painkillers, which can alleviate pain and other disorders. Physicotherapy and foot care are also important, especially for the prevention of complications such as diabetic ulcer.
Despite the challenging management of the neuroses of diabetes, a comprehensive treatment strategy and lifestyle adjustment can significantly improve the quality of life of patients and reduce the occurrence of complications. Early identification and intervention are important strategies to reduce the severe effects of diabetes neurosis.
