Diabetic peripheral neuropathy, patients with paroxysmal or persistent bilateral numbness of hands and feet, tingling, burning sensation, ant crawling sensation or electric shock and other abnormal sensations. This article will popularize science from the causes, clinical signs, treatment and other aspects of diabetic peripheral neuropathy, in order to broaden the knowledge of the majority of diabetic patients, so as to pay attention to the early stage and treatment of diabetic peripheral neuropathy.
I. Definitions It refers to the pathological paresthesia caused by the symmetrical and peripheral nerve lesions mainly involving the distal limbs in diabetic patients when other causes are excluded. It is one of the most common complications of diabetes.
2. Etiology It is mainly caused by hyperglycemia, hyperlipidemia, oxidative stress and other factors, which lead to microcirculation disorders and cell hypoxia, resulting in the damage of neurons and other cells, eventually leading to irreversible damage of neurons, glial cells, vascular endothelial cells and so on, and promoting the occurrence of diabetic neuropathy.
III. Main symptoms 60% ~ 90% of the patients have different degrees of neuropathy, mainly manifested as bilateral limb numbness, socks, tingling, burning, ant crawling or electric shock and other abnormal sensations, some people have stomach distension, vomiting and other gastroparesis, some male patients have sexual dysfunction, impotence and other symptoms.
4. How to prevent and treat 1. Control blood sugar
The incidence and severity of diabetic neuropathy are positively correlated with the duration of hyperglycemia and blood glucose levels, so early control of blood glucose is of great significance.
2. Control blood lipids
Dyslipidemia is a key factor
in the progression of peripheral neuropathy 3. Control blood pressure
Hypertension is an independent risk factor
for the progression of diabetic peripheral neuropathy 4. Improving lifestyle
Healthy lifestyle can reduce the risk of morbidity of diabetic neuropathy. Long-term regular and reasonable exercise can reduce weight, improve lipid metabolism, control blood sugar and blood pressure, and reduce the incidence of diabetic neuropathy.
5. Medication
Neurotrophic: Mecobalamin, epalrestat and lipoic acid are all neurotrophic drugs, which can significantly improve the clinical signs and symptoms, signs and nerve conduction velocity of patients with diabetic neuropathy.
Improvement of microcirculation: alprostadil injection, beraprost sodium, pentoxifylline and pancreatic kininogenase can improve microvascular circulation and diabetic peripheral neuropathy.
6. Traditional Chinese medicine treatment
Dialectical treatment, according to the specific symptoms of patients and tongue and pulse conditions, often use some blood-activating drugs, can improve diabetic peripheral neuropathy.
In a word, it is advocated to actively carry out health education in diabetic population to help them establish scientific and rational prevention and treatment concepts and objectives, improve the prevention awareness of neuropathy, and enable patients to maintain a healthy lifestyle.
