Summary
Autoimmune Hepatitis, AIH is a chronic inflammatory disease caused by abnormal attacks on liver cells by the organism ‘ s immune system. The purpose of this paper is to provide an overview of the clinical performance, diagnostic methods, treatment strategies and preventive measures of the disease with a view to providing the general public and medical personnel with comprehensive knowledge of the disease and to promoting its early detection and treatment.
Introduction
Self-immunized hepatitis is a disease that wrongfully treats and attacks liver cells as alien by the organism ‘ s immune system, leading to liver damage and inflammation. The incidence of the disease has gradually increased globally, especially among women. Self-immunological hepatitis can lead to abnormal liver function, fibrosis and even cirrhosis and liver failure. It is therefore essential to understand the clinical performance, diagnostic methods, treatment strategies and preventive measures for self-immunizing hepatitis.
Clinical performance
The clinical performance of autoimmune hepatitis is broad and varied, and can be divided into liver and extra-hepatic.
I. Hepatic performance
1. Acute morbidity: Some 30 per cent of patients may be acutely ill, sometimes with an outbreak of liver failure, in the form of signs of yellow salivation, nuance and inactivity.
Chronic diseases: Most patients are invisible until severe liver damage is diagnosed. Common symptoms include yellow stings, scabs, inactivity and possible menstruation among female patients.
Other symptoms: abdominal pain, fever, liver swelling, spleen swelling, spider mole, etc. In the course of the disease, some patients may have cirrhosis of the liver, even of the indemnified liver, accompanied by abdominal and liver cerebral disease.
II. Extra-hepatic performance
1. Conjunctive pathologies: about 63% of patients have at least one evidence of hepatopathic disease, and joint pathologies and joint swelling are more common.
Skin symptoms: About 20 per cent of patients have rashes in the form of polymorphics, rubles or scabies, which can be accompanied by allergies of pelvis, flat moss and lower limb ulcer.
Hematological change: reduction of mild anaemia, white cell and blood plate.
Diagnosis
Diagnosis of self-immuno-hepatitis relies on integrated clinical performance, laboratory examinations, visual examinations and the organization of pathological examinations.
I. Laboratory inspection
1. Sero-immunological examinations: examination of anti-nuclear antibodies (ANA), anti-smoothing muscles (ASM), anti-hepatic renal granular antibodies (LKM-1), and immunoglobin G (IgG) levels.
2. Hepatic function inspection: includes testing of indicators such as acetylene enzyme (ALT), avalina enzyme (AST), alkaline phosphate enzymes (ALP) and gamma-diaamide (gamma-GT).
Imaging
1. Ultrasound: Preliminary assessment of liver structure and morphology, excluding other liver diseases.
2. CT and MRI examinations: help to assess the extent and extent of liver disease and the presence of complications, such as cirrhosis and abdominal water.
Organization of pathological examinations
Hepatitis work is the gold standard for the diagnosis of self-immuno-hepatitis. Hepatological changes in liver tissues, such as lymphocyte and plasma cell immersion, hepatic cell mutagenicity, necrosis, etc. can be observed through hepatic biopsy.
Treatment strategy
Treatment strategies for self-immunizing hepatitis include general treatment, medication and surgical treatment.
I. General treatment
1. Rest and nutrition: It is recommended that patients be careful to rest, avoid overwork and ensure adequate nutritional intake.
2. Avoid incentives: Avoiding the use of drugs that could induce or aggravate the immune hepatitis.
II. Drug treatment
1. Immunosuppressants, such as Penistone, Sulphur, etc., are used to suppress abnormal activities of the immune system and to reduce hepatitis.
Bear deoxychoric acid: contributes to improved cholesterol and liver function.
III. Surgery
In cases of serious illness or ineffective medication, surgical treatment such as liver transplants may need to be considered.
Preventive measures
1. Prevention of autoimmune hepatitis depends primarily on avoiding exposure to susceptibility factors, maintaining good living habits and actively treating primary diseases.
2. Avoiding exposure to susceptibility factors: avoiding close contact with patients with their own immuno-hepatitis and reducing the risk of viral infection.
Maintaining good habits of life: maintaining adequate sleep and avoiding overwork; balancing diets with appropriate intake of fresh vegetables and fruit; avoiding alcohol and tobacco consumption.
3. Actively treat primary diseases: self-immunological diseases such as systematic red erythalamus and rheumatism can induce self-immuno-hepatitis and should be actively treated.
Conclusions
Hepatitis autoimmune is a chronic inflammatory disease caused by abnormal attacks on liver cells by the organism ‘ s immune system. It has a wide range of clinical performances, including liver and external. Diagnosis relies on integrated clinical performance, laboratory examinations, visual examinations and the organization of pathology examinations. The treatment strategy includes general treatment, medication and surgical treatment. Preventive measures include, inter alia, avoiding exposure to susceptibility factors, maintaining good living habits and actively treating primary diseases. Through early detection and treatment, the prognosis of self-immunized hepatitis can be significantly improved.
Self-immunizing hepatitis
