Antibacterial drugs are our powerful weapon in the fight against bacterial infection. However, many do not know that different types of antibacterial drugs have a very different time frame for their best use, and that the correct timing of antibacterial drugs plays a crucial role in their efficacy. First look at penicillin-type antibacterial drugs, which are more effective when taken in the empty abdomen. As food affects the absorption of penicillin-like drugs and increases in stomach acids after eating, gastric acids can damage the structure of penicillin and reduce its bioavailability. For example, in Amosilin, one hour before or two hours after the meal, a drug is used to enter the intestinal tract more quickly, so that it is fully absorbed and better microbicideed.
The situation is relatively complex with respect to antibacterial drugs of a herbicide. Most of the drugs, such as sepsis, are less affected by food, but some of them have special requirements. For example, a high concentration of blood medicine in the abdominal abdominal use can reach an effective antibacterial concentration more quickly, but can also be taken after meals if there is a person with a gastrointestinal discomfort, although the peak of blood medicine may decrease, but can reduce the irritation to the gastrointestinal tract. Perfluorooctone, on the other hand, needs to be taken after meals, as food can facilitate its absorption and increase its bioavailability.
There are also characteristics of the Great Ringed ester antibacterials. Archicillin is more appropriate one hour before or two hours after meals. This is because food reduces the absorption rate of AchCin, but does not have a significant impact on absorption. However, given the potential for gastrointestinal irritation of Achicin, patients who are more sensitive to the gastrointestinal tract can also be taken after eating a small amount of food. Unlike erythrin, which is more irritating to gastric mucous membranes when it is empty, and is prone to nausea, vomiting, etc., it is generally recommended to be taken after 3 – 4 hours or 1 – 2 hours before the meal, which ensures a certain absorption effect and reduces adverse effects.
In antibacterial drugs such as quinone, left oxen fluorine is generally not affected by food and can be taken before or after meals. However, if the patient suffers from a gastrointestinal discomfort after taking it, he or she may choose to take it after eating. Nofluorinated salsa stars are required to be taken in the abdomen and are unfit for food for two hours before and after the drug is taken, as food significantly reduces their absorption and affects antibacterial effects. For some time-dependent antibacterial drugs, such as beta-neamide (including most varieties of penicillin and headgillin), the microbicide effect of the drug depends mainly on the concentration of the blood drug above the lowest antibacterial concentration (MIC). As a result, such drugs usually require multiple deliveries of drugs over one day to maintain effective blood concentration. For example, Amosilin is generally required to provide drugs every 6 – 8 hours, which ensures that the concentration of blood drugs is higher than that of MIC for most of the day and that bacteria are continuously suppressed and eliminated.
In contrast, concentrations are dependent on some varieties of antibacterial drugs, such as amino sugar sluice and quinone, which are associated with peak concentrations of drugs. In the case of such drugs, an appropriate increase in the single dose and an increase in the interval between the drugs can increase the efficacy of the treatment while reducing the incidence of adverse effects. For example, Quintacolin, by rationalizing the dose and the time given, can reduce the damage to kidneys and hearing while ensuring antibacterial effects.
In addition, the time spent on anti-bacterial drugs takes into account the individual circumstances of the patient. For older persons, the absorption, distribution, metabolic and excretion processes of drugs in the body are likely to change due to a decrease in gastrointestinal functions and body metabolic capacity. When choosing the time to take anti-bacterial drugs, greater attention should be paid to the tolerance of the gastrointestinal tract. If there is serious gastrointestinal discomfort when the antibacterial drug is administered in the air by older persons, even if the drug is theoretically required to be emptied, it can be appropriately adapted to be taken after meals or in the same way as a small amount of food.
For children, due to their ability to swallow and the degree of acceptance of the taste of drugs, the time given also needs to be flexible. For example, some bitter antibacterial drugs may cause vomiting if they are administered to children before meals, in which case they can be administered to children after meals, and can be appropriately given sweet drinks to alleviate the pain. At the same time, the liver and kidney function of the child is not fully developed, and it is important to avoid the accumulation of drugs in the body in determining the time and dose of the drug.
In the use of anti-bacterial drugs, attention is also paid to the effects of interactions with other drugs or foods on the length of treatment. If both anti-acid and some antibacterial drugs are taken, anti-acid drugs may change the acidity of the stomach and thus affect the absorption of antibacterial drugs. For example, antiacids containing aluminium and magnesium are combined with tetracyclic antibacterials, creating insoluble combinations and reducing the absorption of tetracycline. Therefore, if both types of drugs need to be used at the same time, there should be a 2-3 hour interval.
The right time for antibacterial drugs is an important component of rational use. It not only increases the antibacterial effects of drugs but also reduces the occurrence of adverse effects. Whether the drug is prescribed by a doctor or administered by a patient, it is important to be fully aware of the properties of the antibacterial drug and to determine the optimal time for the drug, depending on the type of drug, the patient ‘ s individual situation and the possible interaction, so that it can better serve our health.
