Immunoplasia can cause anaemia?


Immune Thrombocytopenia (ITP) is a self-immunological disease characterized by the wrongful attack and destruction of the plate by the immune system, resulting in a decrease in the slab count. The ITP usually does not lead directly to anaemia, but in some cases, ITP patients may experience anaemia, usually due to other factors or complications in the course of the disease. The following is a detailed explanation of the relationship between immune slab reduction and anaemia:Basic Concept of the ITPThe ITP is the result of abnormal human immune systems that produce self-activated antibodies for the slabs, which are combined with the slabs, resulting in the premature destruction of the slabs in the body or the inhibition of their production in the bone marrow. A reduction in the slab would increase the risk of haemorrhage, particularly from skin and mucous membranes, such as purple plaster and nose.Basic concept of anaemiaAnaemia is a blood disease characterized by low erythrocyte count or insufficient haemoglobin levels, which results in insufficient oxygen to the body tissue. Anaemia is caused by a variety of causes, including malnutrition, chronic diseases, genetic diseases and blood loss.Relationship between ITP and anaemia1. ITP usually does not directly cause anaemiaThe ITP mainly affects the platelets, while anaemia is associated with red cells. Therefore, the ITP itself does not usually lead directly to anaemia. The erythrocyte count and haemoglobin levels of ITP patients are usually normal.2. Indirect causes of anaemia due to ITPAlthough ITP does not usually lead directly to anaemia, ITP patients may suffer from anaemia if:Chronic haemorrhage: As a result of the reduction in the platelet of the IMP, the patient may have chronic or repeated haemorrhages, such as nosebleeds, dental haemorrhages or digestive bleeding. Chronic haemorrhage consumes iron reserves in the body, leading to iron deficiency anaemia.Bone marrow inhibition: In very few cases, ITP may affect the functioning of the marrow, affecting not only the production of slabs but also the formation of red cells, leading to anaemia.Drug side effects: The treatment of certain IPP drugs, such as cortical steroids, may affect the formation of red cells and lead to anaemia.Self-immunological diseases: ITPs may coexist with other self-immunological diseases, such as systematic erythalamus (SLE), which can cause anaemia.Malnutrition: IPP patients may have poorer appetites due to symptoms of the disease itself or to the treatment of side effects, leading to malnutrition and, consequently, anaemia.Diagnosis and treatment of anaemiaIf an ITP patient suffers from symptoms of anaemia, such as fatigue, dizziness or pale skin, the doctor makes the following diagnosis:Blood testing: The whole blood cell count (CBC) can assess the erythrocyte count and haemoglobin levels.Iron metabolic examinations: seroton, iron protein and total iron combined to determine if there is a lack of iron.Vitamin B12 and folic acid levels: A deficiency of these nutrients also leads to anaemia.Osteo-marrow examination: In some cases, it may be necessary to conduct a bone marrow biopsy to assess bone marrow function.The treatment of anaemia depends on its causes:Iron: If anemia is caused by a lack of iron, it can be treated by oral or intravenous iron.Vitamin B12 and folic acid supplementation: If anaemia is due to these nutrient deficiencies, the corresponding vitamin supplement is required.Treatment of primary diseases: control of the ITP itself, reduction of haemorrhage and prevention of further haemorrhage.Blood transfusion: In the case of severe anaemia, blood transfusion may be required to rapidly increase haemoglobin levels.ConclusionsImmunoplasia per se does not directly lead to anaemia, but it is likely to occur due to chronic haemorrhage, bone marrow inhibition, drug side effects, co-existence of self-immunological diseases and malnutrition. Therefore, in addition to the reduction in the treatment of IPP patients, there is a need to monitor the presence of symptoms and signs of anaemia and to provide timely diagnosis and treatment. Through comprehensive management, anaemia among ITP patients can be effectively controlled and the quality of life improved.