Infective shock: life versus pathogen death

Infective shock is a major challenge in the area of serious diseases, where pathogenic micro-organisms and their toxins enter the human body and cause inflammatory reaction syndromes in the whole body, leading to cyclic disorders and cell metabolic disorders. The onset of the disease and its dangerousness, like a sudden storm, engulfed the lives and health of the patients, placing enormous stress and testing on medical treatment.Infective shock includes bacteria, viruses, fungi, parasites, etc. Among them, the internal toxin produced by grenacella-negative bacteria such as coli, pneumocococcal, and the external toxin released by grenacin-positive bacteria such as golden and strepella are common infectious shock “beast”. When the body’s immune capacity is reduced or the number of pathogenic bacteria is high and toxic, these pathogenic bacteria can enter the human body through a variety of means, including the respiratory, digestive, urinary and skin wounds, thereby releasing the toxin from a wide range of reproductions, thus inducing a full-body inflammation response.The uncontrolled release of inflammatory media plays a key role in the outbreak mechanisms of infectious shock. When pathogens and their toxins activate the organism’s immune cells, they release a large number of inflammatory media, such as tumour necrosis-alpha, white gin-1, white gin-6, which are like “flammation signals” and are transmitted rapidly in the body, triggering vascular cell damage, increased vascular penetration, micro-circumulation disorders and blood-flow modification. Following the destruction of the inside of the veins, liquids and proteins in the veins seep out into the inter-organization gap, thereby reducing the amount of effective cyclic blood; micro-cycling disorders prevent tissue organs from receiving sufficient blood injections, cells from oxygen deficiency and metabolic disorders, leading to organ dysfunction and even functional failure. At the same time, the inflammatory medium can act directly on the heart, inhibiting myocardial constriction, thereby reducing the volume of heart discharges and further exacerbating cyclic failure. The clinical manifestations of infectious shock are complex and varied, and the conditions are developing rapidly. Patients tend to start with symptoms of a full-body inflammation, such as high heat or low body temperature, cold war, accelerated heart rate, and acute breathing. As the condition evolves, the symptoms of shock gradually appear. Blood pressure decreases significantly, with a constriction pressure below 90 mm mercury column or lower, and a reduced pulse pressure. Skin mucous membranes become pale, wet and cold, and the hips of the limbs end up as a result of constriction of the exterior veins and insufficient blood infusion. There has been a significant decrease in urine, even without urine, which is an expression of insufficient renal infusion, impaired functioning, and the possibility that patients may suffer from cognitive disorders, which have evolved from irritation to coma, reflecting serious effects on brain blood infusion and oxygen supply. Corresponding symptoms can also occur as a result of impairment of the function of the organs, such as bloated liver, blood condensation, gastrointestinal disorders, nausea, vomiting, diarrhoea, digestive haemorrhage, etc.Diagnosis of infectious shock requires a combination of factors, and detailed medical history inquiries are essential to understand whether the patient has a recent history of infection, including the area, symptoms, treatment, etc. During medical examinations, emphasis is placed on changes in vital signs such as body temperature, blood pressure, heart rate, breathing, etc., as well as signs of organ systems such as skin mucous membrane, heart lung, abdominal, etc. Regular blood testing often shows an abnormal increase or decrease in white cell count, an increase in the proportion of neutral particles and a possible nuclear left transfer, and therefore laboratory testing is an important basis for diagnosis; blood culture is able to identify the origin of the disease and provide anti-infection precision treatment. However, in order to increase the positive rate, attention should be paid to the collection of specimens prior to the use of antibacterials; C-responding to the rise in inflammation indicators such as protein and calcium reduction, haematological analysis provides an understanding of the alkali balance of infected patients in shock, with low osteopaeemia and hyperlacidemia. In addition, video science screenings such as chest X-rays, CTs, ultrasounds can help to detect infections such as lung infections, abdominal sepsis, etc.The treatment of infectious shock requires time races and multidisciplinary collaboration. Rapid blood capacity needs to be replenished and blood injections restored, often with a combination of crystall fluids such as physico-saline water, lactation lactation lignite lactation, and gel fluids such as protein, hydroxyethyl starch, which can quickly supplement the extra-cell fluid capacity, while gel fluids maintain vascular impregnation pressure for long periods and reduce fluid seepage. In the process of expansion, indicators such as blood pressure, heart rate, urine, central intravenous pressure of patients need to be closely monitored to assess the recovery of blood capacity and to adjust the velocity and quantity of rehydration and to avoid complications such as shock or excess rehydration resulting in CPR failure.Anti-infection treatment is central to the treatment of infectious shock. In the case of potentially pathogenic micro-organisms, broad spectrum, strong antibiotics should be used at an early and empirical stage, and the results of blood culture and drug sensitivity tests, once available, need to be adapted to sensitive antibiotics in a timely manner. Antibiotics are used in sufficient doses and treatments to ensure that pathogens are completely eliminated and that re-emerging infections are prevented. At the same time, active treatment of infection stoves, such as abscess-to-scillation and the removal of dead tissues, is essential to control the source of infection.The rational application of vascularly active drugs improves the circulatory function of patients. The most common drugs are dopamine, gonaline, adrenaline, etc. Due to the different doses, dopamine can be used in different receptors at different doses, with a major dopamine receptor of dopamine and an increase in renal blood flow at small doses; a β receptor at medium doses to enhance myocardial condensation and heart rate; and an α receptor at large doses to vascular constriction. Derenalin is mainly active in alpha receptors and has a strong vascular constrictive effect, which is effective in increasing blood pressure, but is used with close monitoring of exterior vascular infusion to avoid excessive vascular constriction leading to an increase in tissue deficiency. Adrenalin is highly excusable for alpha and beta receptors and can be used when the effects of other drugs are not apparent, but may increase the risk of cardiac disorders because of its strong excavation to the heart. The use of vascularly active drugs should be carried out on the basis of full amplification, and the dose adjusted to the individualisation of the patient ‘ s blood pressure, heart rate, tissue infusion, etc.In addition, there is a need to strengthen support for and protection of the functions of organs. For patients with respiratory failure, oxygen therapy and mechanical ventilation are provided in a timely manner, and the oxygen and ventilation functions are maintained to prevent further damage to the organism by low oxygen haemorrhage and carbon dioxide retention. Renal function support can help remove metabolic waste and excess moisture from the body, maintain the alkali balance and electrolyte stability in the human body, such as blood dialysis, dialysis and diarrhea, and severely require renal therapy. The gastrointestinal function supports the use of proton pump inhibitors to prevent stressor ulcer, the provision of intestinal fungi to regulate intestinal strains, the early implementation of intestinal nutritional support, assistance in the reduction of bacterial transfer and the absorption of internal toxins, among other things, while taking care to maintain the functional stability of the patient ‘ s coagulation function, liver work, and other dirty system.The pre-pregnosis of infectious shock is related to a number of factors, such as the basic health status of the patient, age, the type and virulence of the infected pathogens, and the timely and correct diagnosis and treatment. While there has been significant progress in the treatment of infectious shock in modern medicine, the overall mortality rate remains relatively high. So, prevent an infectious shock. Attention is being paid to improving personal hygiene and prevention of infection in daily life; the treatment of chronic diseases and those with low immune capacity is being actively carried out to improve the body ‘ s immunity; and, in health-care facilities, to reduce the risk of an infectious shock, to safeguard life and health, to strictly observe the principle of sterile operation, to rationally use antibiotics and to strengthen the prevention and control of infection.