It’s about skin disease.

Skin disease: The challenge of “scrutinizing” the body, which is like a hidden “sculptor” in medicine, is silently changing the contours and quality of the patient, posing a double physical and mental challenge. Skin disease is a conjunctive tissue disease characterized by skin inflammation, variability, thickening and fibrosis, which in turn hardens and shrinks, with multiple internal organs, such as heart, lungs, kidneys and digestive tracts, for which the causes of the disease have not yet been fully identified and which are now considered to be related to the interaction of genetic, environmental and immune factors. On the basis of genetic susceptibility, environmental factors such as long-term exposure to certain chemicals (e.g. PVC, organic solvents, etc.), as well as pollution of thallium dust, may cause disease. Anomalous activation of the immune system plays a key role in the onset of rigid cortex disease, with its own immune response leading to overmobilization of fibre cells, large amounts of extracellular matrix components, such as synthetic glue, deposited in skin and internal organs, leading to tissue fibrosis and hardening. Clinical performance in the case of skin disease varies according to the degree of the disease and its stress and location. Skin pathologies are usually the first known anomalies. Early in a disease, the skin of the patient may be swollen in the hand, face, etc., with a change in the intestine of the finger and a gradual increase in skin tension. As the condition progressed, the skin began to become hard, thicker, inelastic, with a reduced face, a limited mouth, like a mask, medically known as the “face mask”. Sclerosis of the skin can also overwhelm the limbs and the torso, severely limiting the patient ‘ s joint activity, leading to convulsions, malformations and an impact on daily life and self-care. In addition to skin presentation, rigid skin diseases often involve internal organs. The digestive system is more common, and patients suffer from such symptoms as osmosis difficulties, heart burns, and back-flow symptoms as a result of reduced oesophagus cortexation, and sub-ecophagus disorders. Severely, it can lead to a narrow diet, which affects food intake and causes malnutrition. Pulmonary stress can be seen in the form of IPT, pulmonary artery high pressure, etc. The patient suffers from respiratory difficulties, short-temperature and lack of strength, and, as the condition increases, the pulmonary function declines, seriously affecting the quality of life and the prognosis. Heart stress can cause cardiac fibrosis, cardiac inflammation, etc., causing cardiovascular complications such as cardiac disorders and heart failure. Nephrosis is also one of the serious complications of hard-skin diseases, which can result in protein urine, kidney failure, etc., endangering the life of the patient. The diagnosis of hard-skin disease is a process of comprehensive diagnosis. Doctors are asked in detail about the patient ‘ s medical history, including the order in which the symptoms appear, their duration, and whether there are incentives. The medical examination focuses on the hardness, thickness, elasticity of the skin, as well as the degree of joint activity and the presence of internal organs. In terms of laboratory examinations, seroscopy shows that anti-nucleus (ANA) positives, particularly Scl-70, are more specific to systemic rigid diseases. In addition, it is possible to conduct a dermal biopsy to observe the fibrosis of skin tissues and inflammation of inflammated cells through pathological examinations, which can help to identify the diagnosis. The treatment of hard-skin diseases is a long and complex process, the main aim of which is to prevent new skin and dirty organs from becoming tired, to improve existing symptoms and to improve the quality of life of patients. Drug treatment is at the heart of treatment for hard-skin diseases. Immunosuppressants such as cyclophosphollides and methamidophos-phosphony inhibit the abnormal activation of the immune system, reducing inflammation response and fibrosis progress. Sugar cortex hormones can play an inflammatory role in the early stages of a disease or in cases of stress on important organs, but as their long-term use may have more adverse effects, they need to be used with caution and closely monitored. Angiogens such as calcium ion stressor can be used for vascular pathologies to improve blood circulation and to reduce the Reno phenomenon (white, purple, red when the finger is cold or emotional). Symptoms of the digestive system can be mitigated by the use of acidics, motor-promoting drugs, etc. In the case of complications such as inter-pulmonary pathologies and pulmonary artery high pressure, treatments are to be used in combination with the conditions and the effects of treatment are to be assessed on a regular basis. People with rigid skins also need careful self-management in their daily lives. Care is taken to keep warm, especially at the end of the limbs, to avoid cold irritation to induce or increase vascular convulsions. Stop smoking because it increases vascular disease and affects blood circulation. Appropriate skin care, skin cleanness, and the use of mild skins to avoid drying and broken skin. For patients whose joint activity is restricted, rehabilitation and exercise, such as physiotherapy, joint activity training, etc., may be conducted under the guidance of a doctor to prevent further corrosiveness and rigidity of the joint. In terms of diet, nutritional balance is ensured, with increased intake of high-quality proteins and vitamins to maintain normal metabolic and organizational rehabilitation of the body. Despite the enormous pain and challenges that it poses to patients, as a result of the continued development of medicine, the level of early diagnosis and comprehensive treatment has improved, and patients can still maintain a better state of life, as far as possible, in their struggle against the disease, slowing the progress of the disease and regaining the confidence and hope of life as long as they cooperate actively with it and maintain self-management.