It’s important to know how to use the double-edged sword of antibiotics.

It is well known that penicillin was a powerful antibiotics, a “smart instrument” for the treatment of bacterial infections during World War II, and saved countless lives during World War II. However, with the widespread use of penicillin and other antibacterial drugs, even at random in life, or over-reliance on antibiotics and their abuse, and slowly over time, the first “super bacteria” in history — the methoxysilin-resistant golden grapeoccus — has emerged, followed by an increasing number of “superbacterial bacteria”. As reports of “superbacterials” continue to emerge, there are concerns about antibiotic resistance. It is clear that the emergence of “super bacteria” is no longer merely a concern of medical workers and has become a global problem. How do we respond to that problem and challenge? First of all, there should be no panic about superb bacteria, and we need to understand the reasons for its creation and the mechanisms for its dissemination in order to deal well with the problem. “Superbacterial bacteria” is not, in fact, specific to a specific bacteria, but is a generic reference to bacteria that show resistance to at least three types of clinically commonly used antibacterial drugs, with an academic name called “multi-drug resistant bacteria”. First of all, let us know about our drug-resistant fungus, which, according to the China Bacteria Resistance Monitoring Network, is the main clinical challenge facing our country, mainly in terms of resistance to carbon-cyanolic antibacterials. Data on the severity of the problem of bacterial resistance in the country, such as data from the first half of 2023, show an alarming 79.5 per cent resistance of Boeman to carbon-cyclyacne-resistant drugs. And what about abroad and globally? In 2022, the authoritative medical journal, The Lancet, published a study of 204 countries and territories around the globe in 2019, which showed that antibacterial drug resistance directly resulted in more than 1 million deaths, even more than deaths from malaria or HIV infection; the number of indirect deaths was even more striking: nearly 5 million. As early as 2016, a global study on drug-resistant infections commissioned by the British Government indicated that as many as 10 million people were expected to lose their lives each year by 2050 as a result of drug resistance. Why does the drug “deactivate” the bacteria? What can we do to change this? Let’s first understand how bacterial resistance is created. The resistance of bacteria is in fact the result of the natural choice of bacteria in the process of evolution, and in the process of their growth and reproduction, the reasons for their promotion involve a number of aspects, such as the mutation or mutation of bacteria, the improper use of drugs and the reduction of the body’s immunity, all of which may be potential causes of resistance. And the abuse of antibacterial drugs is an important factor in bacterial resistance, and it is also a changeable condition that we humans are able to raise our awareness. The problem of “abuse” is manifested mainly in two ways: the irrational use in the treatment of human diseases and the excessive and inappropriate use in livestock. As a result of antibacterial drug choice pressure, those bacteria that are resistant to drugs are naturally selected and prolific, thus accelerating their reproduction and spread. It is essential that the general public raise awareness of antibiotics and change the “misperception” of anti-bacterial drugs and move out of areas of abuse. The problem of drug abuse became widespread because of the relatively limited knowledge of anti-bacterial drugs. What’s wrong with common antibacterials? We sum up the following 10 misconceptions, which need to be corrected as soon as possible: 1. Ignorance of the causes of cold, and the use of antibacterial drugs once the cold is acquired; 2. Heat is the first antibacterial drug of choice; 3. Antibacterial drugs are all-powerful antibacterial drugs, using antibiotics when reference is made to “inflammation”; 4. Diarrhea is inflammation, with the best use of antibacterial drugs; 5. In one or two days, unheated or poorly treated, frequent changes in antibacterial drugs are considered to be the best, with greater resistance, and treatment tends to be better than a narrow-spectral antibacterial drug for a particular pathogen; 7. It is considered that new and expensive antibacterial drugs are the most effective; 8. general infections are combined with a variety of antibacterial drugs that seek rapid and effective control of infections blindly; 9. The use of medicines is not standardized, insufficient and signs are improved. 10. In the winter and spring, the high incidence of respiratory diseases is self-preventing against the use of antibacterial drugs. Full awareness of the dangers of antibiotics! 1. Antibacterial drug abuse not only causes bacterial resistance problems, but also leads to a series of serious adverse effects, of which allergies are particularly common. General allergies can be manifested in skin aching, rashes, etc., and even life-threatening conditions such as an allergic shock can occur in serious cases; even some drugs can cause nervous system symptoms, such as headaches, dizziness, etc.; some antibacterial drugs can also have a toxic effect on hearing and kidneys, which is why some patients suffer from deafness and acute renal failure; and the abuse of antibacterial drugs can also disrupt the body ‘ s population and cause a strain of the fungus, which causes a large number of inhibited bacteria to reproduce and cause secondary infections. V. Awareness-raising to regulate the use of drugs to prevent drug resistance. 1. Non-discretionary: In the use of antibiotics, medical advice should be followed to ensure that they are taken after a professional diagnosis and that they are not misused blindly, especially in the case of minor diseases in general (e.g., flu, diarrhoea). 2. Non-consumption of medicines: Almost all antibiotics are prescription drugs, which must be purchased on the basis of a medical prescription and free from any choice of online or physical pharmacies. 3. Do not be self-righteous: the choice of antibacterial drugs should be made by a professional physician on the basis of the medical condition and the results of clinical tests, rather than on the sole basis of advertising or other person ‘ s propaganda or personal experience. 4. Do not stop or change drugs at will: once they are used in accordance with the instructions of a doctor, they are taken on time, at dosage and during the course of treatment, and they are not stopped or replaced without permission. 5. Discarding drugs: Obsolete drugs are hazardous waste and should be placed in hazardous waste cans to avoid the recycling of illicit elements. Waste is classified in advance and protection is provided for others. 6. Focusing on personal hygiene to prevent infection and infection: handwashing, ventilating and avoiding close contact with patients help to prevent infection and infection. 7. Enhancement of physical exercise: Sticking to physical exercise to enhance body strength and immunity, reducing the use of antibacterial drugs from source and contributing to early recovery. Finally, it is hoped that more attention and learning will be given to the use of antibiotics, that awareness will be raised to change the abuse of antibiotics and that the production of resistant bacteria will be reduced, so that antibiotics will be better served.