Ankylosing Spondylitis, AS, is a chronic inflammatory disease that mainly affects the spinal and pelvis joints, especially the pelvis. Over time, this inflammation may lead to the integration of parts of the spine (vertebrae), reduce the flexibility of the spine and eventually lead to bow positions. If the ribs are exhausted, it may be difficult for the patient to complete a deep breath. The disease falls into one of the types of spinal arthritis, which is dominated by the middle axle joints and may be accompanied by extra joints such as eye inflammation, heart problems, etc.
Causes of morbidity
The exact cause of the disease is not yet entirely clear, but studies have shown that it is associated with genetic factors, environmental factors and immune system disorders.
Genetic factors: Strong direct spinal traction is highly associated with the human white cell antigen (HLA)-B27 gene. The risk of a direct spinal disease among the population carrying the gene has increased significantly, but not all the carriers have a disease, suggesting that other factors are involved.
2. Environmental factors: Some environmental factors, such as infections, may be associated with the onset of a direct spinal disease. For example, certain intestinal and urinary tract infections can trigger or exacerbate conditions.
3. Immunopathy: Direct spinal disease is considered to be an autoimmune disease, and patients ‘ immune systems wrongly attack their own joints and spinal cords, causing inflammation.
Clinical performance
Symptoms of direct spinal disease usually begin to appear in late adolescence or early adulthood, with men more common than women. Early symptoms may include:
1. back pain and rigidity: especially when it is more visible in the morning or after a long period of inactivity and when it is reduced.
2. Limited spinal activity: As the condition progresses, the flexibility of the spinal column gradually decreases, resulting in restricted activity.
3. Inflammation of the sepsis: Inflammation, such as foot and pain, can occur in the parts of the bone attached to the sepsis and lurch.
4. Peripheral joints: Great joints such as hips and shoulder joints may be affected.
5. Excursions of the joints: Includes eye inflammation (perinitis), heart problems and lung problems.
Treatment
The treatment of direct spinal disease aims to alleviate symptoms, control inflammation, maintain joint activity and improve the quality of life. Treatment includes:
1. Drug treatment: Inflammatory anti-inflammatory drugs (NSAIDs) for pain and inflammation; programme control anti-generative drugs (DMARDs) such as nitrous sulfur and ammonium butterflies; biological agents, including tumour cause of death (TNF) inhibitors and white cell 17 (IL-17) inhibitors, are particularly effective in controlling the condition.
Physicotherapy, which includes thermal therapy, motor therapy, etc., helps maintain joint flexibility and muscle strength.
3. Surgical treatment: In some cases, if the hip is seriously damaged, it may require a joint replacement operation.
Lifestyle regulation: includes regular exercise, maintenance of the right position and good sleep habits.
5. Psychological support: Psychological support and counselling are also important for the overall management of patients because of the potential for chronic pain and a decline in the quality of life as a result of direct spina.
Straight spinal disease is a chronic disease that, although currently incurable, can be effectively controlled and improve the quality of life of patients through comprehensive treatment and lifestyle adjustments.
