Summary: The mesotoxic coronary is a serious complication based on multiple intestinal diseases, characterized by acute illness, rapid progress and poor prognosis. The purpose of this paper is to raise public awareness of the disease, promote early detection, timely treatment and reduce its morbidity and mortality.
Introduction
It can occur in the course of a variety of intestinal diseases, such as ulcer colonitis, cronosis and infectious colonitis. In the event of an illness, failure to be treated in a timely and effective manner can lead to serious consequences such as intestinal perforation, sepsis and shock, which pose a great threat to the life and health of the patient. Therefore, a better understanding of the knowledge of the virulent coronary, both for medical professionals and for the general public, is of great importance.
II. Causes of illness
(i) Inflammatory enteropathy
The most common underlying diseases are ulcer and cronosis. In these cases, the intestinal tract is chronically infested, with repeated damage to, and repair of, the intestinal wall mucous membranes, resulting in abnormal intestinal structure and function. When inflammation occurs acutely and is not effectively controlled, inflammation can spread to the whole of the intestinal wall, causing intestinal smooth muscle palsy, expansion and, in turn, medium-toxic cortex.
(ii) Infectious colonitis
Some bacteria (e.g., hard-to-work, Shiga, etc.), viruses (e.g., mega-cell viruses) or parasites can lead to severe intestinal inflammation responses. If the infection is not treated in a timely manner, the inflammation continues to increase, and it can also induce toxic giant colons. For example, pseudo-film intestinal inflammation caused by hard-to-scortosis infections can progress to medium-toxic giant colons when the condition deteriorates.
(iii) Other factors
The long-term use of certain drugs, such as opioid laxatives, anticholined drugs and so on, may inhibit intestinal creeping, build up intestinal content, increase intestinal pressure and increase the risk of dysentery disease. In addition, intestinal ischaemic blood, radioactive damage, etc. may also disrupt the normal structure and functioning of the intestinal tract and create the conditions for the occurrence of cytotoxic giant colons.
III. METHODOLOGY
The intestinal inflammation has increased dramatically as a result of underlying intestinal diseases or causes, with a large number of inflammating cells immersing in the intestinal wall, and the release of inflammable media, such as cancer cause of death – alpha, white-cell media – 1. These inflammatory media can lead to intestinal dyslexic retrenchment and lower intestinal dyslexia, which in turn can expand the intestinal cavity. At the same time, inflammation can cause intestinal nervous system disorders, further exacerbating intestinal worm function anomalies. As the intestinal cavity expands, the pressure inside the intestinal wall rises rapidly, affecting, on the one hand, the blood circulation of the intestinal wall, leading to intestine hemorrhage, anaerobic insufficiency and further exacerbation of the intestinal wall damage, on the other hand, the thinness of the intestinal wall and its susceptibility to perforation and the introduction of bacteria and toxins in the intestinal tract into the abdominal cavity, causing serious complications such as perititis and sepsis.
IV. Clinical performance
(i) All-body symptoms
Patients often experience high heat and temperatures of over 39°C, with symptoms of systemic intoxication such as cold warfare, inefficiency, dehydration and electrolytic disorders. As a result of severe infections and intestinal disorders, patients can quickly experience shock, such as reduced blood pressure, accelerated heart rate, pale skin and cold limbs.
(ii) Abdominal symptoms
The main manifestation is abdominal abdominal abdominal swelling, with a marked and sexual increase, which can be accompanied by abdominal abdominal ache and absonic pain, but may not be apparent at an early stage. As a result of intestinal palsy, the patient usually stops ventilating, defecating, and the intestinal tingling is reduced or disappeared. Some of the patients can be sick, vomiting, and vomiting is more of a stomach content or with gall.
V. Diagnosis
(i) Medical history and clinical performance
A detailed inquiry into the patient ‘ s history of inflammation, intestinal infections, etc., combined with typical clinical performances such as high heat, abdominal swelling, abdominal pain, and cessation of ventilatory defecation, leads to a prima facie suspicion of a toxic coliform. However, these symptoms are not specific and need to be further examined for diagnosis.
(ii) Laboratory inspection
1. Regular blood testing: a significant increase in white cell count and an increase in the proportion of meso-particle cells, suggesting a severe inflammatory response. It can also be accompanied by anaemic conditions and a decrease in the number of slabs, reflecting the overall condition of the patient.
2. Blood biochemical examination: Electrolytic disorders, such as low potassium haemorrhage, low sodium haemorrhage, and abnormal liver and kidney function. Inflammation indicators, such as C, reaction proteins, blood sank, etc., have increased significantly.
3. Excrement screening: For a large, medium-toxic colon that is suspected of infectious colonitis, faeces are cultured to detect fungi, such as the detection of a difficult scortoxin, which helps to diagnose a difficult scortoxin.
(iii) Visual inspection
1. Abdominal X-line examination: Visible colon expansion with a diameter of up to 6 cm across the colon, thinness of the intestine wall, disappearance of the colon bag, with a gaseous plane.
2. CT Examination: A clearer picture of the extent, extent of colon expansion, enteric wall thickness, oedema, and the presence of complications such as abdominal fluids, perforations, is of great value for diagnosis and assessment of the condition.
(iv) Endoscopy
When the condition is relatively stable, it is observed directly that the mucous membranes, such as mucous membrane, oedema, ulcers, ulcers etc., but during the acute period of the meso-toxic giant colon, the endoscopy is at risk of intestine penetration due to the high expansion and thinness of the intestinal wall, which requires careful operation or avoidance.
Treatment
(i) General treatment
Patients should immediately fast and depress their stomachs in order to reduce intestinal stress and promote intestinal rest. (b) Provide intravenous rehydration, correct dehydration, electrolyte disorders and acid alkali balance disorders, supplement sufficient nutrients such as heat, protein, vitamins, and maintain the basic vital signs and nutritional needs of patients. At the same time, the vital signs, abdominal symptoms and signs of patients, as well as laboratory examination indicators, are closely monitored and the treatment programme adjusted in a timely manner.
(ii) Drug treatment
1. For the treatment of pathogens: in the case of inflammatory intestinal diseases, the dose of sugar cortex hormones or immunosuppressants should be increased in order to control intestinal inflammation; in the case of infectious intestinal inflammation, anti-infection treatment with sensitive antibiotics, such as nitrazine, vancomacin (for difficult scafrost infections), etc., should be used.
2. Gastrointestinal promotive drugs: are generally banned because of the potential for intestine expansion or perforation.
(iii) Surgery
Surgery should be considered when:
1. Intestinal piercing: This is an absolute indicator of the operation, which requires immediate surgery to repair or colon fistula in order to prevent further abdominal infections.
2. Large-scale haemorrhage: haemorrhage in the intestine, which has not been treated in a conservative manner by the internal medicine, which should be surgically stopped and the intestines removed.
3. Severe colon expansion: After 24 – 48 hours of active internal medical treatment, colon expansion has not improved or continues to increase, and surgical interventions, such as colonectomy or colon fistula, should be considered in order to avoid intestine ischaemic necrosis and perforation.
Prevention
(i) Active treatment of basic diseases
In cases of inflammatory enteropathy, intestinal infections, etc., the medical treatment must be regulated, reviewed regularly, and the conditions strictly controlled, so as to avoid acute and aggravated inflammation.
(ii) Reasonable use of medicines
In the use of drugs that may affect intestinal creeping, the need and risk should be carefully assessed to avoid the long-term or unreasonable use of laxatives, anticholines, etc.
(iii) Early identification and intervention
In case of an increase in abdominal swelling, abdominal pain or fever in patients with intestinal diseases, medical treatment should be provided in a timely manner, early diagnosis and effective treatment measures should be taken to prevent the development of a moderately toxic coronary.
Conclusions
It is a serious intestinal coronary complication, the occurrence of which is linked to multiple factors, the risk of clinical performance and the need for a combination of diagnosis and treatment. By raising awareness of the medium-toxic coronary, raising public health awareness and placing emphasis on the early treatment and prevention of intestinal diseases, it can be effective in reducing morbidity and mortality, improving patients ‘ prognosis and safeguarding intestinal health.
It’s a very toxic colon.
