Negative response of emergency clinical antibacterial drugs: risks of use that cannot be ignored

Antibacterial drugs are an important weapon in the treatment of infectious diseases in clinical emergencies. However, these drugs are not without risk, and their adverse effects may cause different levels of harm to patients. Understanding the adverse effects of anti-bacterial drugs is essential for the proper use of drugs by emergency medical personnel and for the safety of patients.I. Allergies: the most common and potentially fatal adverse reactionsAllergies are the more common types of adverse effects in antibacterial drug use. In the case of penicillin, for example, it is a widely used antibacterial drug, but the incidence of allergies is relatively high. Slight allergies may be manifested in skin symptoms such as rashes, itchings, measles, etc., which usually occur shortly after the medication is administered and can be spread throughout the body or confined to a particular part. Serious allergies are allergies, and patients can experience rapid signs of a sharp drop in blood pressure, respiratory difficulties, increased heart rate, and loss of consciousness, which, if not saved in time, can endanger life in a short time. Antibiotics of peptoxin can also cause allergies, although they are similar to the chemical structure of penicillin, but they are not absolute, although special care is required in the use of peptoxin in patients with a history of severe allergy of penicillin. Prior to the use of these allergy antibacterial drugs, detailed questioning of the patient ‘ s allergy history and the conduct of a pictorial test are essential precautions.Hepatic toxicity: risk of potential liver damageSome antibacterial drugs are liver toxic and may affect the normal function of the liver. For example, erythycin in the Great Ringed Irogen antibiotics, long-term or large-dose use may result in abnormal liver function, in the form of ammonium enzymes, yellow sluice, etc. This is because erythrin may interfere with certain metabolic enzymes in liver cells during liver metabolic processes, affecting normal metabolic and detoxification functions in liver cells. Also, tetracyclic antibiotics can cause liver damage, especially when used by women during pregnancy, which can increase the liver burden and even cause serious complications such as acute fatty liver. Therefore, the liver function of patients should be monitored on a regular basis when using antibacterial drugs of hepatotoxicity, especially for patients with underlying liver diseases or chronic drug use.III. Renal toxicity: threats to kidney functionAminocin antibiotics such as Quincin and Amikane are known for their significant kidney toxicity. This type of drug is excreted mainly through the kidneys, which, when accumulated within the kidneys, can cause damage to the epipelagic cell in the kidney tube, leading to a reduction in the kidney function. Patients may experience increases in protein urine, blood urine, blood acetic anhydride and urea nitrogen, which can develop into kidney failure in serious cases. The elderly, children, and patients whose kidney function is self-inflicted are more vulnerable to the renal toxicity of amino-cluceous drugs. In addition, there is a certain renal toxicity for aluminum antibiotics, such as vancocin, which also requires close monitoring of the kidney function, adjusting the dose of the drug to the kidney function and the time between its use to reduce the risk of renal toxicity.IV. Gastrointestinal response: influence on the digestive function of patients and drug dependenceMany antibacterial drugs cause gastrointestinal responses, which cause discomfort and may affect the smooth running of treatment. Antibiotics such as quinone can lead to symptoms of nausea, vomiting, abdominal pain and diarrhoea. This is because such drugs stimulate gastrointestinal mucous membranes, affecting normal creeping and digestive fluids in the gastrointestinal tract. Some of the drugs in the β-neamide antibiotics can also cause gastrointestinal discomfort, such as Amocrin, which can lead to mild nausea and appetite. For patients with higher gastrointestinal reaction, self-restraint can be caused by the insufferability of these symptoms, thus affecting the effectiveness of antibacterial treatment. Thus, in the course of drug use, attention should be paid to the gastrointestinal response of the patient, with appropriate treatment or adjustment programmes, if necessary.V. Illnesses in the blood system: influence on blood function and condensation mechanismsCertain antibacterial drugs can have adverse effects on the blood system. Clocin has been used with caution for causing serious adverse blood system effects such as regenerative obstructive anaemia. The occurrence of this adverse reaction may be related to the function of chloracin as a inhibitor of bone marrow stem cells, which, when it occurs, tends to be severe and less predictable. In addition, in a few cases, the antibiotics of the hemorrhoids may affect the coagulation function, resulting in prolonged condensation time and increased hemorrhage. Medicines such as Haut Mondo can inhibit the synthesis of vitamin K, which is essential for coagulation, thus indirectly affecting the coagulation function. Therefore, when using these antibacterial drugs that may affect the blood system, indicators such as blood routines, coagulation functions, etc. should be regularly examined in order to detect and address potential blood system problems in a timely manner.VI. Neuro-system adverse reactions: diverse and complex manifestationsAntibacterial drugs may also cause adverse neurological reactions. For example, carbon pyroacnein, e.g., amphetamine, may induce epilepsy in individual patients, especially in patients with incomplete kidneys, which is more likely to occur as a result of slow discharges and higher blood concentrations. This is due to the possible impact of carbon pyroacne on the acceleratory and inhibitive balance of the central nervous system. Antibiotics such as quinone can cause vertigo, headaches, insomnia, tremors and other neurological symptoms, which may also affect the normal functioning of the central nervous system in serious cases. In addition, amino-gluceous antibiotics can cause ear toxicity, damage to hearing and frontal neurons and lead to hearing loss, ringing and dizziness, which is also associated with the accumulation of drugs in ear tissue and damage to nervous cells.VII. Diverse infections: new problems after antibacterial treatmentThe long-term or unreasonable use of anti-bacterial drugs can also cause double infections. When broad-spectrum antibacterial drugs kill a large number of sensitive bacteria in the body, the insensitive or drug-resistant bacteria are used to reproduce in the body, thus causing new infections. For example, with the use of a large number of precipitous antibiotics, patients may suffer from intestinal strains, resulting in hyperbolic growth and pseudofilmic inflammation, manifested in severe diarrhoea, abdominal pain and fever. In addition, there may be cases of double infections in the oral, respiratory and urin systems, such as the infection of white pyroclacteria in the oral or respiratory tract, which can be associated with goose acne, cough and cough.The adverse effects of antibacterial drugs in emergency clinical care are diverse and of varying severity. When using antibacterial drugs, health-care personnel must be fully aware of these adverse reactions and carefully assess the patient ‘ s physical condition, including age, underlying disease, liver and kidney function, etc., before using the drug; closely monitor the patient ‘ s symptoms, signs and related indicators, such as blood protocol, liver and kidney function, and coagulation function, in the course of the drug; and, in the event of detection of the adverse effects, take timely and appropriate measures, such as stop drugs, adjustment of the drug programme, treatment of the symptoms, etc., in order to minimize the harm caused to the patient by the adverse reaction of the antibacterial drug and to ensure the safety and effectiveness of emergency antibacterial treatment.