Overview of acute upper respiratory tract infection

Acute upper respiratory tract infections mainly involve the sinuses and throat. Most acute upper respiratory tract infections are characterized by mild symptoms, short duration and self-limitation, but they have become one of the most concerned health problems because of their high incidence, and are also the most common diseases in primary health care around the world. Adults often have 2-4 episodes of acute upper respiratory tract infections in a year, while preschool children have an average of 6-10 episodes in the same period.

Most acute upper respiratory infections are caused by viruses, while a few cases are caused by bacterial infections. According to statistics, there are more than 200 respiratory viruses that can cause acute upper respiratory tract infections. The most common viruses include rhinovirus, influenza virus, coronavirus, respiratory syncytial virus, human parainfluenza virus and adenovirus. The most common pathogen of bacterial infection is group a Streptococcus pyogenes. The clinical signs and symptoms of acute upper respiratory tract infection has individual differences, a small part of which is affected by the type of virus infection, while to a large extent, it is related to the age, physiological status and immune regulation of the host. Generally speaking, the symptoms of acute upper respiratory tract infection can be divided into early and late stages. The duration of symptoms varies from 7-10 days and reaches its peak on the 2nd or 3rd day. Symptoms in the early stages include nasal itching, sneezing, throat irritation with occasional chills, headache and discomfort, which gradually appear and resolve 24-48 hours after infection. Late symptoms are nasal and runny nose, sore throat caused by inflammation of the tonsils or adenoids, and cough that occurs within a few days of infection and persists for a week or more.

At present, there is no specific treatment for acute upper respiratory tract infection, so the focus of treatment is to reduce the clinical signs and symptoms of patients. While immunization has been shown to be an effective strategy for mass prevention, leading to a reduction in morbidity or morbidity in vaccinated patients, further studies are needed for many other viral acute upper respiratory tract infections. On the other hand, medical interventions at this stage are aimed at alleviating the symptoms of acute upper respiratory tract infections, and if they are carried out in the early stages of infection, before viral replication has reached its peak, viral replication can be suppressed and disease transmission can be reduced. Therefore, early medical intervention to disrupt the viral replication cycle is of great significance.

Specifically, there are three times that are important for the intervention of acute upper respiratory tract infection. 1. Appearance of symptoms: Intervention immediately after the first appearance of symptoms can reduce the incidence of moderate and severe acute upper respiratory tract infection. It is easier to slow or stop the replication of the virus in the early stages of infection. 2. Symptom progression: Although interventions at this stage may not be as effective in preventing the development of severe acute upper respiratory tract infection or the progression of symptoms, it is still important to minimize the spread of the virus even when symptoms are evident. 3. Asymptomatic people: Those who are in frequent contact with infected people should intervene even if they have no symptoms. Intervention at this stage may disrupt the immune environment for virus binding and replication.

Viscose nasal spray

has been shown to be effective in the early intervention of acute upper respiratory tract infections. Their role is to create a barrier that traps virus particles, thereby preventing the virus from invading the mucous membrane. At the same time, mucus gel nasal spray has broad-spectrum anti-pathogen activity and is effective against a variety of pathogens causing acute upper respiratory tract infections.

Acute upper respiratory tract infection