Parkinson’s Front Line Treatment Outlook

Parkinson’s Front Line Treatment OutlookChief neurologist, Haiguchi People’s HospitalLuo Hyun-taoParkinson ‘ s disease is a chronic and active nervous system disease caused mainly by the degradation of dopamine neurons in the brain. The disease was first described by British doctor James Parkinson in 1817 and named after him.Parkinson ‘ s disease leads to impairment of the patient ‘ s motor function, including tremors, muscle rigidity, slow movement and reduced ability to balance and coordinate. Although Parkinson ‘ s disease is currently incurable, it can be effective in mitigating symptoms and improving the quality of life of patients through drug treatment and other interventions.I. What are the causes of Parkinson ‘ s disease?Currently, the exact cause of Parkinson ‘ s disease is not entirely clear, but studies have shown that a number of factors may be relevant to its occurrence. One important factor is the decrease in dopamine levels in neurons due to the degradation of neurons produced and released by dopamine. In addition, genetic factors are considered to play a role in the incidence of Parkinson’s disease. Some genetic mutations are associated with the development of genetic Parkinson’s disease.II. What were the early manifestations of Parkinson ‘ s disease?The early symptoms of Parkinson’s can be mild and undetectable. Common early performances include:One is tremors. Hand tremors are one of the most common early symptoms, usually during rest periods.Two is muscle stiff. The muscles of Parkinson’s patients may become rigid, leading to inflexibility in exercise.Three is slow. Patients may feel slow and unstable.The capacity for balance and coordination is declining. Parkinson’s may cause difficulties in walking and balancing patients.In addition to these main symptoms, patients may experience other symptoms such as insomnia, depression, constipation and weak voice.III. What are the preventive measures against Parkinson ‘ s disease?Currently, there is no clear way to prevent Parkinson’s disease. However, studies have shown that some healthy lifestyle choices may help to reduce the risk of disease.The first is to maintain a healthy diet and to ingestion of food that is rich in antioxidants and healthy fat, such as fruits, vegetables, whole grains and fish.Second, there is a moderate exercise, where regular physical exercise can maintain physical health and may reduce the risk of disease.Third is to avoid harmful substances and minimize exposure to chemicals harmful to the nervous system, such as pesticides and toxic chemicals.Fourth, good sleep is essential for good health.In the area of Parkinson’s Proactive Treatment Vision, scientists and doctors have been working to find new treatment methods and technologies. The following are some of the cutting-edge studies and clinical applications currently under way.One is cell therapy. It is a way to replace damaged cells by implanting healthy cells or stem cells. Researchers are currently exploring the use of dopamine-generated cells or stem cells to repair damaged dopamine neurons and to restore motor functions.The second is gene therapy. Genetic engineering techniques are used to introduce, modify or delete specific genes to treat diseases. In Parkinsonian treatment, researchers are studying the use of gene therapy to increase the synthesis of dopamine and to mitigate symptoms.The third is deep brain electrical stimulation (DBS). It’s a way to regulate brain activity through implantation of electrodes and through electric stimulation. DBS has been widely applied to Parkinson’s patients and can significantly improve motor functions and reduce symptoms.Fourth is the BMI technology. It is a way to achieve mind control by connecting brain signals to external devices. Researchers are exploring the use of BMI technology to restore the mobility of Parkinsonian patients, for example, by manipulating mechanical arms.Five is drug research and development. Scientists have been working to develop more effective drugs to treat Parkinson’s disease. At present, a number of new drugs are at the clinical trial stage, aimed at improving the functioning of dopamine neurons, mitigating symptoms and delaying the progress of the disease.These frontier studies and clinical applications have given new hope to Parkinson’s patients. The treatment of Parkinson’s disease is a complex and diverse area in which scientists and doctors, through continuous efforts, believe that it will bring better treatment options and hope for Parkinson’s patients.