Quadcyclic drug use and attention
1. Usage (i) Tetracycline 1. Oral common dose of general infections is 0.25 – 0.5g per hour. For chlamydia infections, etc., the procedure is generally 7 – 14 days. Children receive a daily dose of 25 – 50 mg/kg at four doses per day. 2. Vigilante drops 1 – 1.5 g per day for adults 2 – 3 times. Dilution of 5% – 10% of glucose to 0.1% after dripping. Children should be careful with intravenous drugs and, if necessary, dosages should be based on weight. 1. Oral antibacterial and anti-pathogen infections: 0.2 g for first dose, 0.1 g for each subsequent time, 1-2 times a day. The first dose of 4 mg/kg for children over 8 years of age was 1 – 2 times a day for children over 45kg, and the same amount for adults for those over 45kg. Skin infections such as scabies are treated once, twice a day and six weeks as a treatment. 2. An adult dose of 0.1 – 0.2g per day with a 5% glucose injection of 250ml. 1. Oral first dose of 0.2 g for adults, 0.1 g for every 12 hours thereafter. Normal scabies, one 50 mg, two times a day, six weeks for a treatment. Children are generally weighed at 4 mg/kg, with the first dose and 2 mg/kg every 12 hours thereafter.
1. Gastrointestinal reaction 4 cyclic drugs often cause gastrointestinal discomfort, vomiting, abdominal pain and diarrhoea. To mitigate symptoms, medication can be taken after meals. In case of serious gastrointestinal reaction, medical adjustment programmes should be made in a timely manner. 2. Teeth and skeletal effects Such drugs can be combined with calcium and used during the development of the teeth (mid-pregnancy, infants and children under the age of 8 years), leading to yellowness of the teeth, bad growth of the teeth and teeth. At the same time, it can be deposited into the bones, inhibiting their growth. As a result, children under 8 years of age, pregnant women and lactating women are generally banned (Dossi and Minocrin are relatively safe but still need to be cautious). 3. Hepatic toxicity Long-term or large-dose use may cause liver damage, as demonstrated by an increase in remission enzymes. The liver function is regularly examined during the use of the drug, and in the event of an abnormal increase in the liver enzyme, a stoppage should be considered. 1. Drugs with metallic ion four cyclics can form insoluble combinations with metal ion such as calcium, magnesium, aluminium and iron, thus affecting absorption. It is therefore not appropriate to use these metallic ion-containing drugs (e.g. anti-acids, irons, etc.) at the same time, with an interval of 2 – 3 hours. 2. When used with other antibacterial drugs and penicillin, it is not generally recommended to be used because the tetracyclic is a microbicide that may interfere with the fungicide of penicillin. When used in conjunction with other antibacterial drugs, careful assessment is also required. 3. The oral pill may reduce the effect of the oral pill, leading to its failure and other reliable methods of contraception should be used during its use. 1. Pregnant and lactating women, as mentioned above, can enter the foetus through placental barriers, and can also enter the foetus through breast-milk, affecting the teeth and bone development of the foetus and the baby, so that pregnant and lactating women are banned (Dossi cycline and Minocrin are subject to careful use after trade-offs). 2. Older persons 2. The liver and kidney function of older persons may be reduced and will need to be used in a dose-adjusted manner, taking into account the kidney function, while closely observing adverse effects, especially liver toxicity and gastrointestinal response. (iv) Use Note 1. The sun should be avoided during the use of drugs, as some of the tetracyclic drugs increase skin sensitivity to sunlight and are susceptible to phototoxic reactions such as sunburn. 2. When preserving drugs, they shall be kept in accordance with the conditions set forth in the statement of contents and shall normally be subject to avoidance and sealing. In case of discoloration, deodorant etc., do not use. At the same time, the treatment of tetracyclic drugs is based on medical instructions, on a timely and quantitative basis, and does not reduce or decrease the dose to ensure the effectiveness and safety of the treatment. Abnormal symptoms such as rashes, itchings, respiratory difficulties, or severe gastrointestinal disorders, yellow stings, etc. should be immediately discontinued and treated.
