Introduction
Systematic fungi infection is a serious disease that is sometimes encountered in primary health-care institutions. Because of the complexity of their condition, the difficulty of diagnosis and the challenge of treatment, medical personnel are required to have scientific knowledge and methods to improve the effectiveness of treatment and to improve patient prognosis.
Overview of systemic fungi infections
(i) Causes
Infected pathogens of systemic fungi include, inter alia, pyromococcus, fungus, alcoccus, etc. Illuminosis infections are often associated with the long-term use of broad-spectral antibiotics, central intravenous tubes and whole gastrointestinal extragenital nutrients, which disrupt the normal stasis of the human body, causing a large number of membranes to reproduce and enter blood or other tissues. The fungus is widely found in the natural environment, such as soil, air, etc., and is easily infected when people with low immune functions are inhaled into air containing fungus spores. Inhalation occurs mainly through the respiratory tract and can be broadcast throughout the body under immunosuppressive conditions.
(ii) Clinical performance
Patients suffer from a variety of symptoms, with common fever, and temperature can be sustained or intermittently increased. It may also be accompanied by non-specific symptoms such as infirmity, inactivity and wasting. There are different manifestations of stress in different areas, such as coughing, coughing, crumbing, breathing difficulties in the lungs, headache in the central nervous system leading to headaches, dizziness, nausea, vomiting, cognitive disorders, etc., and urinary system irritation in the urine system due to urination, excrement and urinary pain.
III. The application of diagnostic methods in primary health-care institutions
(i) Medical history collection and medical examination
Detailed information is provided on the patient ‘ s medical history, including the recent use of antibiotics, immunosuppressants, the existence of underlying diseases (such as diabetes, malignant neoplasms, AIDS, etc.), the history of surgery, trauma, etc. Medical examinations are comprehensive and care is taken to check whether the skin, mucous membranes, such as rashes, ulcer etc., pulmonary acoustics, abdominal abdominal pains and hepatic spleen swelling. For example, there is a high level of suspicion of fungi infection in patients with chronic antibiotics and an unknown cause of fever.
(ii) Laboratory inspection
Fungi smearing and cultivation
This is the most basic test method. Specimens such as sapling, urine, blood, brain vertebrate, etc. are painted and the form of fungi is observed under microscopes after gland dyeing or special dyeing (e.g., ink dyeing in Indian ink for invisibility test). A fungi culture is also being developed to determine the type of fungi, but the results take some time and may be falsely negative.
2. Serum screening
For example, detection of fungi-specific antigens or antibodies, early diagnosis is facilitated to a certain extent by the detection of lymphoma antigens for pyrocolosis, and semi-emulsin antigens for fungi. Basic medical institutions may choose, on their own terms, appropriate methods of testing, or cooperate with higher-level medical institutions in conducting the examination.
IV. Treatment strategy
(i) General treatment
Patients should be careful to rest, enhance nutritional support and improve the body ‘ s immunity. For people with basic diseases, the treatment of basic diseases, such as the control of blood sugar and the improvement of the functioning of organs, is actively pursued. If the patient has a potential source of infection, such as a central vein, he or she should be removed or replaced in a timely manner.
(ii) Anti-fist drug treatment
1. Penecin B
It is a broad-spectral anti-facter with anti-bacterial activity for many deep fungi. But sexcin B has more side effects, with heat, cold warfare, kidney toxicity, and so on. When used at the grass-roots level, the kidney function and electrolyte need to be closely monitored. It can be used at small doses, with a gradual increase in the dose, while mitigating adverse effects such as antithermal painkillers and sugary cortex hormones.
2. Fluorinated radon
There are better antibacterium effects, especially in the white pyrochlor. The oral intake is good and the side effects are relatively light, and can be used for patients with mild to moderate pyroclastic infections. However, for fungus, etc., the effects are poor and are selected on the basis of the possible type of fungi before use.
3. Ictarconium and Volitconium
It’s good for the fungus, and it’s got some effect on the pyromium. Volcanic antibacterial activity is strong, but it is relatively expensive and there is some drug interaction. In their use, primary care is taken to assess the financial situation of patients and the possibility of drug interaction.
(iii) Treatment process
The treatment of systemic fungi infections is generally long, and in the case of pyromococcal infections, treatment is usually required for weeks or even months; the treatment of fungi infections may be longer, often 3 – 6 months or more. In the course of treatment, a combination of the patient ‘ s symptoms, laboratory results, etc., is used to determine whether the drug can be stopped.
V. Preventive measures
Primary health-care institutions are to strengthen the control of infections in hospitals and strictly adhere to sterile practices, such as disinfection in the operation of central intravenous tubes and urine. Rational use of antibiotics and immunosuppressants to avoid abuse. In the case of high-risk patients, such as those with low immune capacity, preventive anti-fouling measures may be taken, but the trade-offs must be weighed.
Concluding remarks
While primary health-care institutions face many challenges in treating systemic fungi infections, scientific diagnostic methods, sound treatment strategies and effective preventive measures can improve the level of diagnosis and treatment of such diseases, provide better medical care to patients and reduce the serious consequences of systemic fungi infections. At the same time, grass-roots health-care institutions should strengthen their communication and collaboration with higher-level health-care institutions in order to ensure the quality of care for suspected cases and to ensure timely referral.
