In the field of modern medicine against microbacterials, Vungucin is an extremely important antibiotics, especially in the response to the severe glandopositive infection. However, like other drugs, it has some negative effects, of which “red human syndrome” is more visible.
What is the Red Man Syndrome?
The Red Man Syndrome is mainly an adverse reaction in the rapid loss of VAC. The patient’s body has a clear set of symptoms. The most typical expression is the widespread filament of the mucous membrane, as if the whole skin had a red vertigo, which is the origin of the name “Red Man Syndrome”. The skin of the patient ‘ s face, neck, torso, and even the skin of the limbs quickly becomes red, as if it were sunburning, but this change occurred suddenly during the use of the medicine. At the same time, it is often accompanied by the feeling of itching, which may be mildly discomfort or so serious as to make it unbearable for patients to scratch their skin.
In addition to skin symptoms, patients may experience a decrease in blood pressure. This is because the adverse reaction causes an expansion of the blood vessels and lower blood pressure on the veins, leading to symptoms of dizziness, panic, etc. If blood pressure decreases more severely, it may cause more dangerous conditions such as fainting. In addition, some patients are exposed to fever, increased body temperature, and a warmer body, which further exacerbates physical discomfort.
Why is there a Red Man Syndrome?
The mechanism for the occurrence of the Red Man Syndrome is mainly related to the release of ammonium as a result of vancomicin. When Vancocin enters the human body quickly, it stimulates the release of groupamine from fat and alkaline particles. It’s like a “signer” in the body, and it triggers a series of physical reactions. Sytamine expands the skin ‘ s small veins, resulting in redening of the skin. At the same time, vascular permeability increases, and the liquid composition of blood is more likely to see out into the mesoperating gap, causing swollen and itching in the skin. In the cardiovascular system, ammonium causes angiogenesis, reduces blood pressure and affects blood injections of vital organs such as the heart and the brain.
3. How can red human syndrome be prevented?
In order to reduce the occurrence of the Red Man Syndrome, the key is to control the rate of loss of the bets of the vancomycin. In general, Vungucin takes at least 60 minutes to lose. Such a slow loss would allow enough time for the body to adapt to the entry of a drug and reduce the large and rapid release of histamine. Doctors need to adjust the appropriate dose and rate of infusion to the specific circumstances of the patient, such as age, weight, kidney function, etc. In cases of kidney insufficiency, greater care is taken, as metabolism and excretion of drugs in the body may be affected.
What about the Red Man syndrome?
If the patient shows symptoms of the red man syndrome during the use of Vungucin, the first step is to stop the drop. In general, patients with milder symptoms tend to recede with metabolism of the substance as a result of the withdrawal. Antimontamines can be given to mitigate skin itching and other disorders. If the patient ‘ s blood pressure drops significantly, it is necessary to increase the blood supply to the brain and to supplement the fluids as appropriate according to the blood pressure or to use vascularly active drugs to increase the blood pressure.
In short, understanding the negative reaction of the “Red Man Syndrome” of vancomicin is important both for the proper use of medicines by doctors and for the safe treatment of patients, and for ensuring that the adverse effects are minimized while playing the antibactrin function.
