Cron disease is a complex intestinal inflammation disease, with many triggers and rigorous diagnostic criteria. Understanding these aspects is essential for the early identification of diseases, effective treatment and case management.
The causes of Crohn’s disease are numerous. Dietary factors have an immeasurable impact. Long-term ingestion of high sugar, high fat and low-fibre foods, such as Western fast foods and processed snacks, can alter the micro-ecological environment of the intestinal tract and impair the functioning of the intestinal barrier, leading to intestinal inflammation. For example, over-fat ingestion stimulates the increase of cholesterol, and the metabolic abnormalities of choleric acid in the intestinal tract can lead to damage to intestinal mucous membranes and inflammation reactions. Psychopsychiatric factors are also closely related to Crohn ‘ s disease. Chronic stress, anxiety, depression, etc. can affect the neuroendocrine system, leading to intestinal nervous imbalances, intestinal creeping disorders and immunosuppressive disorders, making the intestinal tract more susceptible to inflammation. According to studies, the risk of Cron ‘ s disease is significantly higher for people suffering from severe mental trauma or long periods of stress at work. In addition, smoking is an important incentive. Harmful substances such as nicotine in tobacco can affect intestinal blood circulation, reduce intestinal immunity, damage the integrity of intestinal mucous membranes and create conditions for inflammation.
In the area of diagnosis, there are clear criteria for the diagnosis of Cron disease. The first is clinical performance, with patients often suffering from abdominal pain, diarrhoea and weight loss. The abdominal pain is mostly found in the lower right abdominal or umbilical weeks, with intermittent onset, and can be of the nature of pain or pain, pain or swelling. Diarrhoea is manifested several to more than a dozen times a day and can be defecated, watered or mucous. The decrease in body weight was due to intestinal absorption disorders and loss of nutrients. This is followed by endoscopy and pathological work. Under the intestinal mirrors there are symmetrical changes in the intestinal mucous membranes, asymmetrical changes such as mucous ulcers, changes in pavements, and narrow intestines. The pathological biopsy showed lymphocytes, lymphocytes, lymphocytes, and changes in characteristics such as chromosomal bulge formation. Video-testing also helps diagnoses, such as intestinography, which detects pathologies such as intestines, fistula formation; CT or MRI (CTE/MRE) can clearly show the thickening of intestinal walls, changes in intestinal ectoplasmosis and complications such as sepsis and fistula. In addition, a number of indicators from blood tests, such as increased blood insinuation, C-reacting protein rise and increased white-cell count, can also be used as a basis for assistive diagnosis, suggesting inflammation in the body.
In general, the triggers of Crohn ‘ s disease range from diet to psychiatry to smoking, while its diagnosis requires a combination of clinical performance, endoscopy, video-testing and blood testing. In the case of patients suspected of being Cronian, timely access to medical care and comprehensive and systematic screening for early diagnosis and the development of individualized treatment programmes are of great importance for improving the quality of life of patients.
