Proximate spinal disease is a chronic inflammatory disease that mainly affects the spinal column and the hip, causing pain and rigidity. Although the exact causes of the disease are not yet fully known, certain groups of the population are more vulnerable to the disease. The following are some of the groups of people who are vulnerable to “targeting” the disease:
1. Genetic factors
HLA-B27 Genetic Carrier: HLA-B27 Gene has a strong correlation with a strong direct spinal column. In many cases, the presence of this gene significantly increases the risk of disease. Although not all persons carrying the HLA-B27 gene are sick, about 90 per cent of AS patients carry the gene.
Family history: If there is a history of direct spinal disease in the family, the risk of other family members becoming ill increases. This shows that genetic factors play an important role in the occurrence of diseases.
Age factor
Adolescents and young people: Direct spinal disease usually occurs in adolescents or young adults (15-30 years). This stage of morbidity may be related to the growth and development of the body and to the active state of the immune system.
3. Gender
Men: The incidence of direct spinal disease is significantly higher among men than among women. Although women may also be ill, symptoms are usually light and diagnosis may be more challenging. Higher male morbidity rates may be associated with gender-related genetic and hormone factors.
4. Immunization factors
Immunisation system anomalies: Strong straight spinal disease is a self-immunised disease, and the abnormal response of the immune system may play an important role in the onset of disease. Unusual levels of certain immune system markers may indicate a higher risk of disease.
5. Environmental factors
Lifestyle: Although the direct link between lifestyle and direct spinal disease is less obvious than genetic factors, unhealthy lifestyles can exacerbate symptoms or trigger disease. Smoking, lack of exercise and poor eating habits may affect the course of disease.
Occupational factors: Long-term employment in occupations requiring repeated bending or heavy manual labour may increase the burden of the spine and thus affect the progress of the disease.
6. Other related diseases
Associated diseases: Individuals suffering from certain other autoimmune diseases (e.g., silver crumbs, inflammatory intestinal diseases) may be at increased risk of direct spina. These diseases may share similar immune mechanisms.
Although the exact cause of the disease is not yet fully known, these factors play an important role in the incidence of the disease. For high-risk groups, early identification and intervention can help to slow the progress of the disease and reduce symptoms. Regular medical examinations, healthy lifestyles and attention to their symptoms are important preventive measures. Understanding these risk factors not only facilitates early identification and diagnosis, but also provides guidance for individualized treatment and management. For high-risk groups, especially those with family history or HLA-B27 genes, it is recommended that professional medical examinations be carried out on a regular basis to enable appropriate interventions in the early stages of the disease
Straight spinalitis.
