In the case of gastrointestinal diseases, stomach ulcer is more common, and the difficult ulcer is like an unmanageable “obstinate fortress”, which causes great distress to the health and life of patients and challenges for health workers. Knowledge of difficult ulcer is important for the treatment and rehabilitation of patients.
The incurable ulcer usually refers to a situation in which the ulcer has not been healed or re-emerged in the short term following a standard anti-ulcer treatment programme (e.g. a proton pump inhibitor, an H2 receptor, etc., and adequate treatment). The causes of morbidity are often the result of a combination of factors, making ulcer treatment complex and difficult.
Infection of the fungus (HP) is one of the important factors that leads to incurable ulcer. The ulcer is difficult to heal or is prone to relapse if, during the treatment process, the cholesterol is not completely eradicated and bacteria continue to cause damage to the gastric mucus. Some patients may not be completely eliminated because of irregular drug use, such as self-reducing drug doses, shorter treatment sessions, etc., and thus the ulcer is repeated.
The chronic use of inflammatory drugs (NSAIDs) is also a common cause of difficult ulcer management. Such drugs inhibit the synthesis of prostates within the gastric mucous membranes and weaken the protective barrier of the gastric mucous membranes, whose effects may persist for some time even after a stoppage. Some patients suffering from chronic pain diseases (e.g., arthritis) have difficulty in achieving the desired treatment if the stomach ulcer is not treated effectively, because of the need for long-term use of the NSAIDs.
In addition, gastric acidic abnormalities play a key role in the occurrence of incurable ulcer. Some patients may have high levels of basic gastric acidity or, at certain times, at night, too much gastric acidity, which, even when conventional acidics are used, is not effective in controlling the stimuli of stomach acid to the ulcer, making it difficult to heal. At the same time, inadequate bleeding of the gastric mucous membranes may also affect the repair of ulcer. For example, persons suffering from cardiovascular diseases, due to poor heart blood supply, may suffer from the cycling of the stomach, and the stomach mucous membranes are not provided with adequate nutrition and oxygen, thus slowing the ulcer healing process.
The clinical performance of an incurable ulcer is similar to that of a common stomach ulcer, where the patient usually suffers from abdominal pain, which is of a variety of nature, can be insinuation, swelling, burns or severe pain, etc., and the pain is of a certain regular nature, most of which occurs after eating and may be alleviated as food digests. Some of the patients may also be associated with indigestion symptoms such as anti-acid acids, gas, nausea, vomiting, anorexia and abdominal swelling. Due to the chronic inoculation of ulcer, patients may suffer from body weight loss, anaemia, etc., which seriously affects their nutritional status and quality of life.
The diagnosis of an incurable ulcer requires a full and detailed assessment by the doctor. First, detailed information on the patient ‘ s medical history, including past ulcer treatment, drug history (especially the use of NSAIDs), eating habits, family history and the existence of other chronic diseases, is essential to identify the causes that may lead to ulcer problems. Stomach lenses are an important means of diagnosing the incurable ulcer, by which the ulcer ‘ s parts, size, morphology, depth and surrounding mucous membranes can be directly observed, the ulcer ‘ s degree of healing is determined, and the tissues are examined for pathology in order to exclude the possibility of a malignant disease. At the same time, cholesterol tests are conducted to determine the presence and eradication of cholesterol infection. In addition, special screening methods such as gastric acid genre function determination and gastric mucous membrane blood flow testing have contributed to a better understanding of the physiological function of the patient ‘ s stomach and have provided the basis for the development of accurate treatment programmes.
The treatment of incurable ulcer requires individualized programmes based on the specific causes and individual circumstances of the patient. More intensive eradication programmes should be adopted for patients who are positive for the fungus, which may adjust the type, dose and treatment of antibiotics to ensure that the fungus is completely eliminated and that this factor of continuous gastric mucous damage is eliminated. In the case of incurable ulcer due to the use of NISIDs, where medical conditions permit, use of these drugs should be discontinued or reduced to the extent possible, and more effective gastric mucous protections, such as misopropanol, should be provided to facilitate the repair of the gastric mucous film. In acid treatment, the dose of a proton pump inhibitor may be increased, or combined use of different types of acidics may be used to enhance the inhibition of gastric acids and to create a good environment for ulcer healing. At the same time, there is a need for active treatment for basic diseases, for example, to control cardiovascular diseases and increase the supply of blood to the stomach, and to help heal ulcer.
The treatment of incurable ulcer is difficult but not impossible. Through the rigorous diagnosis of doctors, the development of individualized treatment programmes and the active cooperation of patients, including strict compliance with medical prescriptions, lifestyle adjustments (e.g. regular diets, cessation of alcohol and alcohol, avoidance of overwork and stress), many incurable ulcer patients will eventually be able to heal the ulcer, alleviate symptoms, restore healthy gastrointestinal functions, overcome this “dream fortress” and enjoy a better life.
Stomach ulcer.
