The use of ammonia silin varies depending on the type of infection, age of the patient, kidney function, etc.
• Adults: commonly used for mild to moderate infections. The conventional dosage is 2-4 g per day and is taken four times. For example, when treating mild respiratory tract infections or skin soft tissue infections, it is common to take 0.5-1 grams per hour. This allows for a more stable level of drug concentrations in the body and for sustained antibacterial activity. However, the specific dose also needs to be adjusted to the pathogen of the infection, its severity, etc. The dose may be relatively low in the case of treatment of less serious urinary infections, but it may increase appropriately if the infection is more persistent or there is a risk of resistance. • Children: The oral dose is based on body weight. The average daily dose was 25 – 50 mg/kg, which was also taken in four doses. This is because the physical development of children is not yet complete and drug metabolism and tolerance are different from that of adults. For children of different ages, this dose range ensures that the drug is effective in treating infection while minimizing the occurrence of adverse effects. For example, a five-year-old with a body weight of about 20 kg, the daily dosage is about 0.5 – 1 g per day and is taken four times, each time about 0.125 – 0.25 g. In the course of giving medication, parents are to be careful to see whether the child is indisposed, such as allergies, diarrhoea, etc.
II. Immuno-injection — Adults: Immuno-injection can be used in cases where oral administration is not possible or where a high level of medication is needed quickly. The average dose is 0.5 – 1 g per dose, with a daily dose of 2 – 4 g. For example, when treating infections such as acute tonsilitis, if the patient is unable to take an oral drug, the injection of ammonium sicillin in myitics allows the drug to enter the blood cycle more quickly and act as an antibacterial. However, internal injections may cause adverse effects such as local pains, knots, etc., and after injection care is taken to observe the location of the injection. • Children: dosages of intra-brain injection are also measured by body weight, typically 50 – 100 mg/kg per day, and are given four times. Injection may be painful for children, and medical personnel and parents need to reassure them. Children are also relatively young in their muscles and are required to take care of injection techniques to avoid muscle and nerve damage.
iii. An intravenous injection or an intravenous drip. Adults: In the case of serious infections, such as sepsis, endometriosis, etc., intravenous medicine is a common method. At the time of intravenous injection, the dose was 1 – 2 grams per dose, with a daily dose of 4 – 8 grams. The dose range of intravenous dripping is similar, but the drug is diluted in a suitable amount of infusion, slowly dripping over a period of time. In general, drugs are dissolved in physico-saline or glucose solution, usually for a period of not less than 30 minutes, which reduces the irritation of blood vessels and bodies. For example, in the treatment of bacterial sepsis, a higher dose of ammonium sepsis is required to keep the drug in the blood cycle through intravenous dripping and to combat bacterial infections effectively. • Children: The dose of intravenous drugs is measured by body weight, typically 100 – 200 mg/kg per day, with 2 – 4 times. The vital signs of children, such as heart rate, blood pressure, breathing, etc., as well as the observation of allergies, are closely monitored during the intravenous process. In addition, for patients with reduced kidney function, the dose needs to be adjusted to the kidney function. Since ammonia silin is excreted mainly through kidneys, when kidney function is impaired, the rate of discharge in the body slows, is easy to accumulate in the body and increases the risk of adverse reactions. The dose is usually adjusted to the acetic anhydride removal rate, and the specific adjustment programme needs to be determined by the doctor based on the patient ‘ s kidney function.