Use of and attention to substances of the Greater Ring Irogen
1. For general infections, the usual dose is 1-2g per day, 3-4 times. Children weigh 20 – 50 mg/kg per day at 3 – 4 times. Treatment of Legionellasis, 2 – 4g daily oral sessions for adults. 2-3 times a day for adults. Children weigh 20 – 30 mg/kg per day at 2 – 3 times. It is important to note that drug concentrations should not be too high at intravenous drops and not too fast to reduce vascular irritation. 1. Oral treatment of sexually transmitted diseases caused by trachoma chlamydia or sensitive gonorrhea, with only a single oral dose of 1.0 g. For other infections, 0.5 g of the first day, 0.25 g of the second and fifth days, or 0.5 g of the second day, for three days. Children use body weight for the treatment of ear and pneumonia, 10 mg/kg on day 1 (up to 0.5g on day), and 5 mg/kg on day 2 – 5 (up to 0.25g on day). 2. Vector dripping. Fully dissolved by appropriate injections of AchCin into 0.1 g/ml and added to 0.9% of sodium chloride or 5% of glucose injections in 250 ml or 500 ml, resulting in a final concentration of AchCin of 1.0 – 2.0 mg/ml, with a intravenous drip of not less than 60 minutes. The adult dose was 0.5 g per dose per day for at least two consecutive days. 1. The common dose for adults is 0.25 g per hour per oral dose and 0.5 g per hour per serious infection. Depending on the severity of the infection, 6 – 14 days of continuous administration. Children are given a daily weight of 15 mg/kg in two.
1. The gastrointestinal reaction is more common in gastrointestinal disorders such as nausea, vomiting, abdominal pain, diarrhoea, etc. Care should be taken during the use of the drug to observe that it may continue to be used if the symptoms are light, and if the symptoms seriously affect the quality of life, it may be necessary to adjust the dose or stop the drug. 2. Hepatic toxicity Some of the Great Ringed ester-type drugs (e.g. erythrin esters) can cause hepatotoxicity in the form of ammonium enzyme rise, yellow slurry, etc. The liver function is checked regularly during the course of the drug use, especially at long-term or large doses. In the event of an abnormal liver function, the medication should be stopped and treated in a timely manner. (ii) Drug interactions 1. The co-use of other antibacterial drugs, large cyclic esters with chlorocycin or ricin, which can be resistant due to similar mechanisms of action, should be avoided. 2. With cardiovascular drugs Certain large cyclic esters (e.g. erythrin) can inhibit cytochrome P450 enzyme, co-exist with some cardiovascular drugs (e.g., geo-hosin), which can increase the concentration of the latter ‘ s blood and increase the risk of adverse reactions such as cardiac abnormalities, while closely monitoring the concentration of geo-hosin. 3. Co-use with anti-fouling drugs, such as ketol, increases the concentration of the latter ‘ s blood and increases the likelihood of an adverse reaction, with dose adjustments if necessary. 1. Pregnant and lactating women While the current information shows that it is available under certain conditions, a trade-off needs to be made. If necessary, this should be done under the direction of a doctor. 2. Children are to be used in a way that is strictly measured on the basis of weight, with regard to the choice of a drug (e.g., a dry-suspensant suitable for the child) to ensure safe and effective use. Attention should also be paid to children ‘ s post-pharmaceutical responses, in particular changes in gastrointestinal and liver function. 3. Older persons. The liver and kidney function of older persons may be reduced to varying degrees, and drug use needs to adjust the dose to their physical condition, while closely observing the occurrence of adverse effects. (iv) Use of 1. Large cyclopentone-type drugs are mostly time-dependent antibacterial drugs, and therefore there is a need to ensure sufficient frequency of delivery in order to maintain effective blood drug concentrations to optimize antibacterial effects. 2. In the course of their use, allergies such as rashes, itching and so forth should be stopped immediately and treated accordingly. At the same time, the medication is kept under the conditions required by the instructions in order to ensure its quality.
